1 tablet Zoloft 50 mg (100 mg) contains sertraline hydrochloride 0.05 g (0.1 g). Auxiliary components: calcium dihydrogen phosphate, MCC, hydroxypropylcellulose, sodium carboxymethyl-starch, magnesium stearate, HPMC, macrogol, polysorbates, titanium dioxide.
Sertraline is the active ingredient in Zoloft. He stops the reagent (reverse capture) of serotonin, which is performed by the neurons that have isolated it. As a result, the concentration of the neurotransmitter increases in the synaptic gap and the main cause of depressive states, the serotonin deficiency, is eliminated.
The effect on serotonin receptors causes a significant correction of the mental state of patients with depression. It manifests itself in heightening the mood, eliminating phobias, anxious states, reducing feelings of melancholy, and reducing appetite. The drug acts on 5-HT receptors. On the reagent of norepinephrine, dopamine is weakly affected. There was no sedative, cardiotoxic effect, anticholinergic effect and stimulation effect. Zoloft does not provoke the formation of dependence. Long-term therapy can lead to a decrease in the activity of adrenaline receptors in the brain.
Indications for use
Zoloft is prescribed for the treatment and prevention of relapses with:
– depressive states;
– social phobia;
– obsessive-compulsive disorder (ROC);
– depression with manic conditions;
– panic disorder;
with depression with a sense of anxiety;
– panic disorder with agoraphobia;
– Post-traumatic depressive disorders.
Mode of application
Take Zoloft tablets inside. The dose prescribed by the doctor is consumed in the morning or in the evening once a day. To assimilate Zoloft, food is not affected.
Two weeks is a necessary break between taking Zoloft and MAO inhibitors, to prevent possible fatal complications.
In diseases of the liver Zoloft prescribed in reduced compared with the usual dosages.
Zoloft’s influence on psychomotor functions has not been noted, but the risk of side effects with reduced attention and concentration, impaired vision, when deciding whether to drive can be taken into account. When working with dangerous mechanisms during the reception of Zoloft, you must be extremely careful.