The following is information on contraindications to the use of azithromycin in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should azithromycin not be used?
In the case of hypersensitivity to azithromycin and erythromycin, to other macrolide antibiotics or to ketolide antibiotics, the active substance should not be used. The same applies to infections caused by bacteria, which have already proved to be resistant to several other antibiotics (especially erythromycin and methicillin) (multi-resistant).
Azithromycin should not be used in cases of hepatic impairment or high-grade renal impairment (creatinine clearance below 40 milliliters per minute). There is a risk of delayed elimination and thus of overdosage.
Azithromycin may cause cardiac arrhythmia. Cardiac patients should therefore be monitored carefully while using the drug.
Like all antibiotics, azithromycin destroys the natural intestinal flora. Therefore, there is a risk of severe diarrheal disease when used and for up to two months thereafter. If diarrhea occurs, contact the doctor immediately.
What should you watch out for during pregnancy and lactation?
Azithromycin should only be used during pregnancy after consultation with the doctor, as the safety of using azithromycin has not been established at this time.
It is known that azithromycin passes into breast milk and thus into the baby. This can lead to a disruption of the intestinal flora, which can lead to diarrhea or intestinal inflammation by Sproßpilzbesiedelung. In addition, there is the possibility of sensitization of the infant, that is, in a later contact with azithromycin could lead to an allergic reaction. For these reasons, the drug should also be used during breast-feeding only after consultation with the attending physician.
What should be considered in children?
Children may take azithromycin for the treatment of acute infections. Preventive treatment of children and adolescents with immunodeficiency is not allowed.
For children weighing less than 45 kilograms, the active ingredient should only be given as a suspension (for drinking).
Warnings and Precautions
- To prevent cardiac arrhythmia in a timely manner, regular medical checks on blood potassium levels are required.
- If you experience severe diarrhea during and after taking the medicine, seek medical advice immediately.
- Side effects of the drug may affect the ability to drive and use the machine.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.