Below you will find information on contraindications to the use of Yasmin in general, during pregnancy and lactation, and in children. Please note that the contraindications may vary depending on the drug formulation of a drug (for example, tablet, syringe, ointment).
When should Yasmin not be used?
The use of Yasmin should be stopped immediately at:
- Hypersensitivity to any of the active ingredients of the combination
- Pregnancy and lactation
- existing or previous malignant tumors that would continue to grow with the administration of oestradiol (such as breast cancer )
- Herpes infections in a previous pregnancy (herpes gestationis)
- untreated growths of the uterine lining
- diagnostically unclear bleeding from the vagina
- acute or past severe liver disease (such as liver tumors, liver inflammation, jaundice, biliary congestion, Dubin-Johnson syndrome, Rotor syndrome, and porphyria ), at least as long as certain liver enzymes ( transaminases ) have not normalized
- acute or past blood vessel diseases that have led to vascular occlusions (thrombosis) of arteries or veins such as severe venous diseases, venous thrombosis, phlebitis ( thrombophlebitis ), disorders of blood clotting, pulmonary embolism, stroke, angina pectoris, myocardial infarction and heart valve defects
- difficult to treat high blood pressure
- Diabetes (diabetes mellitus)
- severe lipid metabolism disorders or obesity
- Middle ear deafness, which has worsened during previous pregnancies
- Lupus erythematosus.
Although the active ingredient combination can be used in the following diseases, the physician must check the development of the treatment by continuous monitoring of the corresponding laboratory values and, if necessary, stop the therapy:
- previously occurred phlebitis
- a pronounced tendency to varicose veins
- Increase in blood pressure
- Cardiac and renal dysfunction
- previous minor liver and gallbladder diseases
- Chorea minor (Veitstanz)
- multiple sclerosis
- easier lipid metabolism disorders or considerable overweight
- Diseases of the mammary gland ( mastopathy ).
Taking the active ingredient combination favors the formation of vascular occlusions (thromboses), which can lead to dangerous cardiovascular diseases. This risk can be further increased by additional risk factors such as smoking, high blood pressure, disorders of blood clotting or fat metabolism, as well as previous vascular occlusions and prolonged immobilization (such as bedriddenness).
What should I watch for pregnancy and breastfeeding?
The field of application of Yasmin excludes treatment with the active ingredient combination during pregnancy.
Milk production can be reduced by using the combination of active ingredients. In addition, small amounts of an active substance can pass into breast milk and thus into the baby. In order to avoid damage to the child, it is essential to stop the skin before treatment with the active ingredient.
What should be considered in children?
The field of application excludes treatment of children with the combination of ethinylestradiol and drospirenone.