- Hypersensitivity to the active substance or any other component of the drug;
- Acute ulcer of the stomach or intestines; gastrointestinal bleeding or perforation, gastrointestinal bleeding or perforation in history after the use of a non-steroidal anti-inflammatory drug (NSAID), an acute or recurrent stomach or intestinal ulcer in history;
- Voltaren, like other NSAIDs, is contraindicated in patients who have bronchial asthma attacks, urticaria or acute rhinitis in response to acetylsalicylic acid or other NSAIDs;
- Inflammatory bowel disease (Crohn’s disease or ulcerative colitis);
- Severe hepatic insufficiency;
- Severe renal insufficiency;
- Congestive heart failure;
- Treatment of perioperative pain in aortic coronary artery bypass grafting (or using artificial blood circulation apparatus).
- Ischemic heart disease in patients with angina pectoris suffered a myocardial infarction;
- Cerebrovascular diseases in patients who have suffered a stroke or have episodes of transient ischemic attacks;
- Diseases of the peripheral arteries;
- Third Trimester of Pregnancy.
Concomitant use of Voltaren and systemic non-steroidal anti-inflammatory drugs, such as selective cyclooxygenase-2 inhibitors, should be avoided due to the absence of any evidence of synergistic effects and due to potential additive side effects.
Care should be taken with caution in patients over 65 years of age in accordance with the recommendations for this group of patients. In particular, the use of a minimum effective dose in elderly or low-weight patients is recommended.
As with other non-steroidal anti-inflammatory drugs, including diclofenac, allergic reactions, including anaphylactic/anaphylactoid reactions, can rarely occur even without the prior use of the drug.
Like other NSAIDs, diclofenac can mask its signs and symptoms of infection through its pharmacodynamic properties.