About Trazodone

3.5 rating based on 28 ratings
Rating: 3.3 Reviews: 28
About Trazodone


active ingredient: trazodone hydrochloride;
1 tablet contains: trazodone hydrochloride 75 mg or 150 mg;

Pharmacological effect

The drug has an antidepressant (mood-improving) action, combined with anxiolytic and tranquilizing (anti-anxiety) effect. Pharmacological properties and neurochemical action of the drug differ from typical antidepressants. It does not affect the action of reserpine, weakens the central effects of phenomena and the peripheral action of noradrenaline; does not have a noticeable effect on the neuronal capture of catecholamines, but selectively blocks the seizure of serotonin.

Indications for use

Applied with different forms of depression (suppressed states / endogenous, psychotic, neurotic, somatogenic, etc.), proceeding with anxiety, tension.
Due to the good tolerability and absence of cholinolytic action, trazodone is widely used in the treatment of elderly patients with organic diseases of the central nervous system, as well as in the complex treatment of patients with somatic diseases (diseases of internal organs) complicated by mental disorders (anxiety, tension, etc.).

Mode of application

The initial dose for ingestion is 50 mg 3 times a day, then depending on the type and severity of depression to 300-500 mg per day. Therapeutic effect is usually observed in 3-7 days from the beginning of treatment.
Intravenous and intramuscular injection of 50 mg as an anxiolytic (anti-anxiety) drug for premedication (for anesthesia) before surgery.

Potential Trazodone side effects may include:

Trazodone used to treat the following diseases:


  1. Maureen R. Ambriz says:
    3.0 rating

    Trazodone for Sleep disorders; Depression

    Formation of serotonin syndrome -> internal + external tremor; tachycardia; permanent nausea; Circulatory problems & lt; – since the 3rd day of intake of Trazodone, entry dose 37,5mg / d in the evening. – at higher dosage (up to 75mg / d) symptom intensification ++ from the beginning normalization of sleep behavior All possible dose variants of 20/15/10 / 5mg / d in the morning opposite Cipralex, unfortunately, especially the nausea persists. Current countermeasure with Vomex against the nausea (in the first half of the day) and opipramol 75mg / d in the afternoon + evening against the rest o.g. Symptoms.

    Side effects: Nausea
  2. Joseph D. Hall says:
    1.0 rating

    In the beginning, in any case, slowly creep in, then go some masses

    Side effects: Dizziness; Nausea
  3. Scott L. Blom says:
    4.0 rating

    Have been taking about 3 months Trazodone … Had the drug ever 2 years ago …. Trazodone was the only drug where I was better … Then because of the side effects of 200 mg to 100 mg down because of the strong Fatigue …. Thereafter no therapy success had more (dose probably too low) … now I take about 350 mg and hope that it helps me. had already taken Elontril solo but not the hoped-for Terapierfolg .. only a slight improvement …. Hope that in combination with elontril it is now better … Can Trazodon be combined with Elontril? Please reply……

    Side effects: No side effects
  4. Jo D. Gates says:
    4.0 rating

    Trazodone for Sleep disorders; Depression

    I’ll finally go back to sleep without any problems. I feel much better. 100 mg is sufficient. Side effects are NO more. For the first two days of use, it felt like I was feeling dizzy, but that is now fixed again.

    Side effects: No side effects
  5. Claudia H. Lynch says:
    4.0 rating

    Trazodone for Sleep disorders; Depression

    Only the dose makes, if the desired effect becomes unwanted. For me, a dose of 37.5 mg of the sleep-inducing trazodone is enough to make me sleep and sleep well and to feel good the next morning. At a dose of 50 mg, it is almost like an anesthetic. I’m not able to get up at night.

    Side effects: No side effects