active ingredient: trazodone hydrochloride;
1 tablet contains: trazodone hydrochloride 75 mg or 150 mg;
The drug has an antidepressant (mood-improving) action, combined with anxiolytic and tranquilizing (anti-anxiety) effect. Pharmacological properties and neurochemical action of the drug differ from typical antidepressants. It does not affect the action of reserpine, weakens the central effects of phenomena and the peripheral action of noradrenaline; does not have a noticeable effect on the neuronal capture of catecholamines, but selectively blocks the seizure of serotonin.
Indications for use
Applied with different forms of depression (suppressed states / endogenous, psychotic, neurotic, somatogenic, etc.), proceeding with anxiety, tension.
Due to the good tolerability and absence of cholinolytic action, trazodone is widely used in the treatment of elderly patients with organic diseases of the central nervous system, as well as in the complex treatment of patients with somatic diseases (diseases of internal organs) complicated by mental disorders (anxiety, tension, etc.).
Mode of application
The initial dose for ingestion is 50 mg 3 times a day, then depending on the type and severity of depression to 300-500 mg per day. Therapeutic effect is usually observed in 3-7 days from the beginning of treatment.
Intravenous and intramuscular injection of 50 mg as an anxiolytic (anti-anxiety) drug for premedication (for anesthesia) before surgery.