Hypersensitivity to any component of the drug.
Signs and symptoms of overdose Topamax: cramps, drowsiness, speech and vision disorder, diplopia, mental disorder, coordination impairment, lethargy, stupor, arterial hypotension, abdominal pain, dizziness, anxiety or depression. In most cases, clinical manifestations were not severe, but deaths after overdose were recorded using a combination of several drugs, including topiramate.
Antiepileptic drugs, in particular, Topamax, should be discontinued gradually to minimize the possibility of increasing the frequency of attacks. In clinical trials, doses were reduced by 100 mg at weekly intervals. In some patients, the withdrawal of the drug was accelerated and passed without complications.
The drug is prescribed with caution to children under the age of 2 years.
During treatment with topiramate, an increased incidence of mood disorders and depression is observed.
In cases where the weight of the body decreases during treatment with Topamax, a maintenance diet or enhanced nutrition may be recommended.
During topiramate therapy, it is crucial to adequately increase the amount of fluid used, which may reduce the risk of nephrolithiasis, as well as side effects associated with physical activity and elevated temperatures.