Since Topamax is most commonly used with other antiepileptic drugs, it is not possible to identify which of the drugs caused the development of a side effect.
Central nervous system – nervousness, dizziness, headache, speech and vision impairment, psychomotor retardation, ataxia, fatigability, disturbances of attention, difficulty in remembering, confusion, drowsiness, mental disorientation, anorexia, nystagmus, diplopia, paresthesia , depression; additionally in children – personality disorders, salivation, hyperkinesia; much less often – changes in taste, excitement, cognitive impairment, emotional lability (mood problems), impaired coordination of movements and strokes, apathy, psycho-psychotic symptoms, aggressive reactions; very rarely – suicidal thoughts and attempts, amnesia, and in addition children – hallucinations.
Gastrointestinal tract and hepatobiliary system – dyspeptic phenomena, nausea, abdominal pain, diarrhea, dryness of the lips, rarely – elevation of “liver” transaminases, hepatitis, hepatic insufficiency.
Others – weight loss, asthenia, nephrolithiasis, oligohydritis (mainly in children), metabolic acidosis, fever, and skin and mucosal reactions (erythema, pemphigus, Stevens-Johnson syndrome, toxic epidermal necrolysis, alopecia) in patients who received Topamax together with other drugs that cause reactions from the skin and mucous membranes. Rarely – leukopenia, very rarely – neutropenia. It is possible that a syndrome (usually one month after the start of therapy), characterized by myopia in the background of increased intraocular pressure.