Tamiflu contraindications and warnings


Following is information on contraindications to the use of oseltamivir in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should Oseltamivir not be used?

The active substance should not be used in patients with hypersensitivity to oseltamivir and those with severe kidney disease (creatinine clearance below 10 milliliters per minute).

Renal impairment is not an exclusionary reason for treatment with oseltamivir, but the dose must be adjusted by a physician. There are no dosage recommendations for children with kidney disease. The same applies if, during a global flu outbreak, premature infants under the age of one should be protected from the flu.

In chronic patients, immunocompromised patients or patients with treatment that weakens the immune system, the safety and efficacy of oseltamivir for the treatment or prevention of influenza has not been established. These individuals should only be treated with the drug in exceptional cases.

Whether oseltamivir can protect patients with chronic heart disease or chronic respiratory disease from the complications of influenza has not been clearly demonstrated in studies.

What should you watch out for during pregnancy and lactation?

The use of the active substance in pregnancy and lactation should be done only after a strict risk-benefit assessment by the doctor, since it is not known whether Oseltamivir can harm the child.

What should be considered in children?

In children over the age of one, oseltamivir may be used both for the treatment of influenza infection and for prevention. The dosage is based on weight, and there are no mandatory dosage recommendations for kidney patients.

Children under the age of one may only receive oseltamivir for prevention in the event of a global flu outbreak. For this purpose, a custom-made product from the pharmacy is usually necessary, since the commercial paraffins are too heavily dosed for this age group. The application must be monitored by a doctor. For premature babies, however, there are also no mandatory dosage recommendations.

Warnings and Precautions

  • The drug is not a substitute for a flu shot.
  • The drug is only effective against influenza viruses, not against other types of viruses.
  • The drug is not suitable for severe kidney patients with creatinine clearance below 10 milliliters / minute.
  • Patients being treated with the drug, especially adolescents and children, should be carefully monitored for any behavioral problems.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.