Tamiflu side effects

What side effects can Oseltamivir have?

Below you will find the most important information about possible known side effects of oseltamivir.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).

Oseltamivir has a slightly different side effect distribution in terms of type, severity and frequency in adolescents and adults than in children.

Adolescents and adults
Very common side effects:
headache, nausea

Common side effects: vomiting, pain.

Uncommon side effects:
Hypersensitivity reaction, limited consciousness, seizures, cardiac arrhythmias, elevated liver enzymes, eczema, dermatitis, rash, hives.

Rare side effects:
lack of platelets, allergic shock, excitement, abnormal behavior, anxiety, confusion, delusions, delirium, nightmares, self-injury, blurred vision, gastrointestinal bleeding, bloody pancreatitis, severe liver inflammation, liver failure, blood vessel swelling , severe skin reactions ( erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis).

Children
Very Common Side Effects:
Vomiting.

Common side effects:
Headache, abdominal pain, upper abdominal pain, indigestion, nausea.

Special features:
The frequent and very common side effects occurred in the studies in the patients only once, disappeared despite maintained dosage and in the vast majority of cases did not lead to a discontinuation of therapy.

Post-marketing reports of seizures and delirium (including altered levels of consciousness, confusion, abnormal behavior, delusions, hallucinations, arousal, anxiety, nightmares) in patients with influenza who have received the drug are reported in very few cases led to self-injury or death. These events mainly affected children and adolescents, often appeared abruptly and quickly faded away. Since untreated flu can cause such symptoms, the contribution of oseltamivir is unknown.

What interactions does Oseltamivir show?

Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).

Oseltamivir and its metabolites are eliminated via the kidneys. Therefore, agents that affect kidney function can alter excretion and thus the effects of oseltamivir. These agents include, for example, chlorpropamide, methotrexate, phenylbutazone and the ointment Probenecid.

Potential Tamiflu side effects may include:

Effect
Percentage

19%

12%