About Sutent

3.5 rating based on 29 ratings
Rating: 3.3 Reviews: 29
About Sutent

Sunitinib is used in adults to treat cancers of the supporting connective tissue in abdominal organs. This treatment comes into play when the tumors are not removed by surgery or have already formed secondary tumors. The prerequisite is that prior treatment with the cytostatic imatinib was ineffective or was not tolerated.

What is the purpose of this ingredient?

  • Stop blood supply to new cancer cells
  • inhibit cancer cell growth
  • Preventing the formation of secondary tumors

Sunitinib works

Below you will learn more about the fields of application and the mode of action of sunitinib.
Please also read the information on the drug group cytostatics,
to which the active ingredient sunitinib belongs.

Areas of application of the active substance sunitinib

Sunitinib is used in adults to treat cancers of the supporting connective tissue in abdominal organs. This treatment comes into play when the tumors are not removed by surgery or have already formed secondary tumors. The prerequisite is that prior treatment with the cytostatic imatinib was ineffective or was not tolerated.

Also cancer of the kidney cells adult who has already formed subsidiary tumors can be treated with sunitinib.

In addition, the drug is used to treat adults with non-operable forms of pancreatic cancer that have already formed and are still growing on their offspring.

Sunitinib is rarely used as a first-choice drug. Mostly, pretreatments with other cytotoxic drugs precede it.

For the following application areas of Sunitinib , in-depth information is available:

How Sunitinib Works

Sunitinib belongs to the active ingredient group of cytostatic drugs.

It inhibits various enzymes (tyrosine kinases) associated with cancer growth, the rebuilding of blood vessels to supply the tumor and the development of secondary cancers in cancer.

Potential Sutent side effects may include:

Sutent used to treat the following diseases:

Disease
Percentage
  1. Katerine R. Shank says:
    4.5 rating

    Sutent for Kidney cell carcinoma

    After the 4th therapy, 4 weeks, then 2 weeks, a severe hypofunction of the thyroid occurred.

  2. Jeffrey C. Mielke says:
    3.5 rating

    Sutent for Kidney cell carcinoma

    On May 13, 2014, kidney cancer was more or less accidentally discovered with me because I went to the doctor with pain in my right leg. The pain came from a metastasis of kidney cancer. The kidney was removed 15 days later and a week later I was able to leave the hospital again. But then it actually started really, the metastasis had to be bekämft. Initially, radiation or surgery was out of the question as the metastasis was too large. The surgeon said he needed to take half of my pelvis and bladder off me at this stage. So I did the chemo with Sutent (50) to make the metastasis smaller. On the first day, I had heavy pressure on my chest in the evening and turned green-gray in my face, and it was difficult for me to breathe. The next day it was over again. Then I got diarrhea, constantly vomiting and was always tired. After about 14 days, I got inflammation of the hands and feet, which hurt a lot and restricted the ability to move. The mucous membranes also became inflamed towards the end. The food did not taste as good as usual and everything seemed very spicy. In the following break the Nebenwikungen disappeared after 2-3 days. The CT showed that the metastasis had decreased by about 1/4. Because the drug responded so well, one more cycle was added. The side effects were similar. Instead of puffing I had to burp this time and the Entzündugen hands and feet came a little bit more and more violent. The CT showed that the metastasis had decreased again by about 1/4 to the original size or 1/3 for the last time. So only half the size of the beginning (about 40ccm)! Now, according to the surgeon, surgery is possible. But it is still discussed in the tumor conference, if next comes once again a cycle or the OP.

  3. Paul J. Anderson says:
    3.5 rating

    Sutent for Metastasis; Kidney cell carcinoma

    Take Sutent for one year. Start with 50 mg, due to severe side effects (see later) discontinued after 20 days.After 2 weeks break reduction 37.5 mg.After control with good regression of metastases.After 2 more cycles with 37.5 mg .Control: mixed findings.Then continuous intake of 25 mg.Befundverschlechterung, then again increase to 50 mg.Kontrollbefund (MRI) again regression of the metastases. Side effects: hand-foot syndrome; severe pain and bruises on the feet. Tongue pain, taste disturbances, blood pressure increase, diarrhea, moderate blood picture changes. Against the tongue burning / pain help frozen, fresh pineapple pieces, slowly melt in the mouth, very good. Against the sometimes unbearable foot pain helps Voltaren 50 mg excellently, but respect stomach and blood picture! Ointments: Fortecortril, Nivea, ointment from the Munich urology. Who has other recommendations?

  4. Shane M. Beem says:
    4.0 rating

    I had the complete kidney removed, then I had inoperable lung metastases. SUTENT 50 mg taken in the interval 14 tablets then 7 days break. After more than 2 months again CT. All lung metastases are gone! no tumor remains or signs of disease more detectable.

    Side effects: No side effects
  5. Jack T. Colvin says:
    3.5 rating

    Sutent for Kidney cell carcinoma

    The side effects are all somehow tolerable, except for the deterioration of the values of my remaining kidney. All in all, I put great hope in the drug.

    Side effects: No side effects
  6. Gary H. Wilson says:
    4.0 rating

    Sutent for Kidney cell carcinoma

    15 years ago a kidney was removed. Three years ago, an offspring was diagnosed on the lungs. After almost 3 years without change of the offshoot were deposited on the stomach and duodenum. Thereupon, after nothing was done, it was decided that I start with Sutent. The metastases have declined quite a bit. I take 37.5mg daily without interruption. No side effects until today.

    Side effects: No side effects
  7. Lance H. Bailey says:
    5.0 rating

    Sutent for Kidney cell carcinoma

    Ingestion: 28 days, then 14 days break. Sutient 50mg. ! x monthly. depending on creatinine value 3-4 mg Zometa infusion solution. Side effects: flatulence, diarrhea, changes in taste, salty and spicy no longer taste.Juice on the wrists and shins, mucosal changes in the mouth and anus, bone pain, always cold hands.The side effects come gradually, about after 10-12 days and sound all after 5-6 days after the beginning of the break off again. The drugs work well with me and my metastases have become smaller or at the time no longer detectable. I accept the side effects in view of the success of the therapy. I will even resume my work as a watchmaker in the spring of ’11.

    Side effects: Flatulence; Bone pain; Itching
  8. Martha A. Thetford says:
    3.5 rating

    I take the drug to prevent the reformation of other tumors, I can and must live with the side effects (we try every day new). to repeatedly diarrhea, freezing, rash, weakness, tiredness and so on but until now I think what sölls there is worse, because my humor is my strength! together with my family my best medicine!

    Side effects: Skin rash; Fatigue; Diarrhea
  9. Walter C. Holt says:
    3.0 rating

    Sutent for Metastasis; Kidney cell carcinoma

    I have a lot of side effects, for example: fatigue, rashes on the whole body and mucous membranes, loss of appetite, constipation. But most of the side effects go back in the two-week rest period and then come back stronger in the next cycle.

  10. Brandon B. Weiner says:
    3.0 rating

    Sutent for Kidney cell carcinoma

    For the nosebleeds, problems with aching hands and feet (cracked cornea), body aches and inflammation of the mucous membranes and the increased blood pressure has given us the daily drinking of 1 ltr. Tea helped a lot, the plant is called Jiaogulan. There are even studies by recognized physicians about this plant. Check out the website of Jens Rusch and inform yourself about Jiaogulan. My husband was operated on four years ago, renal cell carcinoma left kidney and tumor 2.5 kilograms. This was followed by further surgery on various lymph nodes and continued intake of Sutent 37.5 mg over 4 weeks and 2 weeks break and that until indefinitely. But we have the side effects quite well under control and will not let us down!

  11. Patsy J. Rowan says:
    3.0 rating

    Sutent for Metastasis

    I found the side effects rather moderate …. they are things that are annoying, but with whom I can live … – diarrhea – loss of taste – sore hands and feet – inflamed mucous membranes (especially in the mouth) – fatigue – loss of appetite – powerlessness

  12. Michael D. Rex says:
    3.0 rating

    Sutent for Metastasis; Kidney cell carcinoma

    white hair, yellow skin color, mucous membranes inflamed, therefore, in the last 10 days of the 4-week intake hardly take meals, if, then diarrhea, therefore, large weight loss, itching, foot problems, sleep disorders

  13. John C. Velasquez says:
    5.0 rating

    Sutent for Metastasis

    I have been taking Sutent since 08/2011. My metastases are on the decline and the side effects (burning in the mouth, pain in the balls of your foot, cracks in the intestinal membrane, high blood pressure, skin redness and abdominal pain) can be endured by taking medication. I can only recommend to anyone, to get information from several doctors about the drug Sutent. There are always new insights. It is important that with each new drug you question how the effect of Sutent is affected. I z. For example, always before taking Sutent, an acid blocker was taken, which, as noted now, reduces the efficiency of Sutent. I have changed this now. So rather 1000 questions too much, as one too few. Good doctors always have an open ear for this. So head up and live on. P. S. Sport, which is workable for you, can also be applied to any & lt; contribute to recovery or better state of mind.

    Side effects: High blood pressure
  14. Arthur A. Jacobs says:
    3.5 rating

    Sutent for Kidney cell carcinoma

    High blood pressure —– Exforge HCT nausea ————– MCP ratioph. and Nux voimika D6 (Homä.) Tiredness ————- Carduus Marianus D4 Tastelessness ——- Luffa operculata D6 Foot syndrome ———– Bellis perennis , Corneal Reducing Cream, Foot Care Diarrhea ————— Loperamide – 1A Pharma

  15. Harrison C. Phung says:
    5.0 rating

    Sutent for Metastasis

    I found out on 15.08.2011 that my kidney tumor (7,5cm), which was removed with my right kidney at that time, has now spread after 8 years. Metastases have been found in the duodenum and in the skull. Due to the dispersion, my doctors have denied an OP and instead started a chemo with Sutent (50mg) and Pamidronate (60mg) – 1.Cycle from 30.08.2011. The first 2 days were very bad, I had very strong limb / bone pain, 38 ° fever and diarrhea. From the 3rd day the pain subsided and I feel better since then. Side effects at this time are: fatigue, small Blisters on the hands, mild diarrhea, pressure in the head. Should others here with a similar diagnosis, please short info, what else comes to me and what YOU think of this treatment.

  16. Gail J. Jackson says:
    4.5 rating

    Sutent for Kidney cell carcinoma

    In March 2010 I had to remove the left kidney and tumor, which proved to be a low-complication procedure. Metastases were detected in the liver and one possible operation was discarded because the metastases were distributed throughout the liver. Since April 2010 now Sutent 50 mg taken in the rhythm of 28 days – 14 days resting with partially increasing side effects of nausea, taste changes, oral inflammation, hand-foot syndrome, depressive mood, water retention i.d. Legs / feet at the beginning of the resting phase. Fatigue, body aches, headaches, skin discoloration and gray hair diminish in the resting phase. Thyroid hyperfunction detected in the third cycle has turned into a subfunction during the fifth cycle.

    Side effects: Headache; Members hurt; Nausea
  17. Samuel S. Riley says:
    3.0 rating

    Sutent for Metastasis; Kidney cell carcinoma

    In Sutent in the first cycle, partly violent nausea with vomiting, severe constipation and bone pain. Two weeks but also ok. The 14-day break unfortunately with severe nausea (half-life of the drug!), And pleurisy. Now, at the beginning of the second cycle, rapids drop sharply to 9.5 (kidney is out), Epo injected. Bisphosphonates so far without side effects