What side effects can buprenorphine have?
Below you will learn the most important about possible known side effects of buprenorphine.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).
Very common side effects:
immobilization, (vertigo) dizziness, fatigue, insomnia, drowsiness, nausea.
Common side effects:
Headache, narrowing of the pupils, dizziness of body position, panting, difficulty in breathing, vomiting, sweating.
Uncommon side effects:
General hypersensitivity reactions, states of confusion, euphoria, nervousness, depression, psychosis-like disorder, delusional disorder, personality disorder, disorientation, moodiness, agitation, speech disorder, nervous discomfort, coma, tremor, fatigue, dry mouth , slurred speech, cramps, lack of muscle control, blurred vision, diplopia, impaired vision, conjunctivitis, tinnitus, palpitations, slow heartbeat, blue discoloration of the skin, arrhythmia (second degree AV block), high blood pressure, pallor, dyspnea, respiratory arrest, constipation, Indigestion, bloating, diarrhea, loss of appetite, itching, rash, tingling, hives, urinary symptoms, urinary retention, weakness, feeling unwell, feeling hot.
Rare side effects:
Decreased appetite, seizures, abnormal motor control.
Very rare side effects:
allergic shock, bronchospasm, blood vessel swelling.
Buprenorphine is on the list of doping prohibited in sports.
When used as a drug substitute, withdrawal symptoms such as restlessness, sweating, cramping or vomiting may occur at the start of treatment.
When used as a sublingual tablet, the oral mucosa may be irritated.
What interactions does buprenorphine show?
Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).
Benzodiazepines (in epilepsy) and MAO inhibitors (for depression) increase the risk of serious side effects and should not be taken concurrently with buprenorphine.
Other opioid painkillers as well as medicines that have a depressant effect on the brain and make it tired (such as anesthetics, hypnotics, sedatives, antihistamines (against allergies), neuroleptics (against mental illness), clonidine (for high blood pressure) and others) increase the effect and / or the depressant effects of buprenorphine. This is especially true for alcohol.
Drugs that reduce the breakdown of buprenorphine in the liver, such as ketoconazole (for fungal diseases), ritonavir, indinavir and saquinavir (all anti-HIV), phenobarbital, carbamazepine, phenytoin (all for epilepsy) or rifampicin (for tuberculosis) Effect and Side Effects of Buprenorphine.