Strattera contraindications and warnings

Contraindications

The following is information on contraindications to the use of Atomoxetine in general, pregnancy, breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should Atomoxetine not be used?

Atomoxetine must not be used with

    • hypersensitivity to the drug

Severe cardiovascular diseases (severe hypertension, cardiac insufficiency, angina pectoris, congenital heart disease, myocardial diseases, myocardial infarction, possibly life-threatening cardiac arrhythmias), blood vessels (arterial circulatory disorders), or disruption of brain blood flow (blood vessel rupture, stroke) ), which can be exacerbated by an increase in blood pressure or heart rate

  • Use of an antidepressant from the drug group of MAO inhibitors
  • Patients with a special form of glaucoma, narrow-angle glaucoma, as atomoxetine caused a morbid dilation of the pupil in clinical trials
  • Development of jaundice or liver damage due to laboratory tests. Here the active ingredient must be discontinued immediately and the treatment must not be resumed.

 

Atomoxetine should be used only with special medical care at

  • Patients prone to low blood pressure because of the risk of further blood pressure drop
  • ECG changes such as a congenital long QT time or a prolongation of the same in the family
  • patients who are not growing sufficiently or gaining enough weight. Here is a long-term treatment with the drug risky
  • Suicidal thoughts or aversion, because they may be exacerbated by the treatment
  • Psychosis and overachievement (mania), as well as aggression, mood swings and epilepsy, because the signs of the disease can be exacerbated by atomoxetine.

Note:
Atomoxetine is not indicated for the treatment of major depressive episodes and / or anxiety disorders.

What should you watch out for during pregnancy and lactation?

Atomoxetine should not be used during pregnancy unless the doctor sees benefit that justifies the risk to the child.

Atomoxetine and / or its degradation products are excreted into the milk in rats. It is not known if atomoxetine is excreted into human milk in humans. Breastfeeding mothers should not use atomoxetine due to insufficient studies.

What should be considered in children?

Atomoxetine should not be used in children less than six years of age because its safety and efficacy have not been established in this age group.

Warnings and Precautions

  • The decision on the use of the drug may only be made after a very careful medical assessment of the child or adolescent.
  • The medicine should only be used as part of a course of treatment with additional non-medical methods.
  • Treatment with the drug should only be started and supervised by a physician experienced in ADHD.
  • In case of liver dysfunction, dosing should be reduced by half or one quarter, depending on the disease severity.
  • Blood pressure and pulse must be checked regularly. These values should be recorded after each dose change and then at least every six months and should be reported to the physician.
  • If there are signs of heart problems, consult a cardiologist immediately.
  • Driving a car or operating machinery can be dangerous because of the limitation on drug performance.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.