Following is information on contraindications to the use of mesalazine in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should mesalazine not be used?
The drug should not be used at
- Hypersensitivity reactions to aminosalicylates
- severe liver dysfunction
- severe renal impairment.
Only after careful consideration of the benefit and risk by the physician and under his control may mesalazine be used in
- mild to moderate hepatic dysfunction.
- history of myocardial or pericarditis, which was allergic
- pre-existing gastric and duodenal ulcers
- increased bleeding tendency
- older patients because they often have impaired kidney function.
What should you watch out for during pregnancy and lactation?
The effects of mesalazine in pregnancy have not been adequately studied. Therefore, the drug should also be used in the form of suppositories or rectal foam only if the doctor deems it necessary.
When mesalazine is used by nursing mothers, it is found in breast milk. The active ingredient is taken up with the milk by the infant and causes diarrhea. If the doctor considers the treatment of the mother absolutely necessary, it should therefore be weaned.
What should be considered in children?
The use of mesalazine in children in the form of tablets and suppositories varies according to the manufacturer. Therefore, read the package leaflet carefully or consult a doctor or pharmacist.
The use of mesalazine clysters is only allowed in children over the age of six. In this case you will only receive half the adult dosage.
Rectal foam with mesalazine must not be used in children above the age of 12 years.
Warnings and Precautions
- Blood and urine levels should be checked regularly by the doctor.
- If cramps, acute abdominal pain, fever, severe headache and skin rashes occur during treatment, discontinue treatment immediately.
- In patients with impaired lung function or asthma, careful medical supervision is necessary.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.