About Salofalk

3.0 rating based on 45 ratings
Rating: 3 Reviews: 45
About Salofalk

Mesalazine is used in inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. The aim of the treatment is to heal the inflammation and alleviate the symptoms it causes: pain and diarrhea.

What is the purpose of this ingredient?

  • Inhibit inflammation
  • Relieve pain
  • Improve Diarrhea

This is how Mesalazine works

Below you will learn more about the fields of application and the mode of action of mesalazine.
Please also read the information on the drug groups anti-inflammatory, aminosalicylates, to which the active ingredient mesalazine belongs.

Application of the active substance mesalazine

Mesalazine is used in inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis. The aim of the treatment is to heal the inflammation and alleviate the symptoms it causes: pain and diarrhea.

Melsalazine can be given either by taking it in the form of tablets or by introducing it into the intestine in the form of suppositories, rectal foam or clysters.

More detailed information is available on the following Mesalazin application areas:

  • chronic inflammatory bowel disease

Mode of action of mesalazine

Patients with inflammatory bowel disease suffer from severe abdominal pain and diarrhea. Typically, the disorders are not uniform. There are periods of intense inflammatory activity and severe discomfort with interim periods in which patients are almost symptom free. In the affected persons strongly increased concentrations of endogenous inflammation-promoting substances such as prostaglandins, leukotrienes and interleukins are to be found in the intestinal mucous membranes.

Like all active substances from the group of aminosalicylates, mesalazine blocks the production of these inflammatory mediators and thus has an anti-inflammatory effect. With the drug, the symptoms can be combated in an acute phase of the disease, but it can also prevent relapses in seizure-free time.

Because mesalazine is not absorbed into the rest of the body, it only works locally in the gut and has few side effects.

Potential Salofalk side effects may include:

Salofalk used to treat the following diseases:

  1. Constance H. Scully says:
    2.0 rating

    Salofalk for Ulcerative colitis

    In a 10-day dose of 3 x 1000 mg Salofalk, after two months of massive hair loss to baldness, hormonal imbalance, thyroid disorder, sweating, depression ..

    Side effects: Sweats; Depressions; Hair loss
  2. Donald P. Dean says:
    3.5 rating

    Salofalk for Ulcerative colitis

    – sweats, nervousness and tremors

    Side effects: Sweats
  3. Mary R. Yates says:
    2.0 rating

    Salofalk for Morbus crohn

    Initially 40 mg prednisolone, effect occurred immediately but as a side effect depression, anxiety, at dose of 2 mg of renewed arthritis.

    Side effects: Depressions
  4. Joanne G. Chambers says:
    3.0 rating

    Salofalk for Ulcerative colitis

    Absolutely disgusting taste! With a drug for the treatment of chronic diseases, it is to be expected that it does not break one and has no strong taste. Treatment had to be stopped and yet an acute episode occurred during the intake time.

    Side effects: Anorexia; Diarrhea; Nausea
  5. Barbara V. Thornton says:
    2.0 rating

    Salofalk for Ulcerative colitis

    I sweat from both drugs at night. The upper body is wet, so the clothes have to be changed at night. Since taking the medication, the chair has become diarrhea-like.

    Side effects: Sweat; Diarrhea
  6. Patsy J. Dinwiddie says:
    5.0 rating

    Salofalk for Ulcerative colitis

    I had the first colitis attack of my life 4 years ago and had to go to hospital for 4 weeks. A pancolitis ulcerosa was diagnosed. I have been treated with 3,000 mg of Salofalk right from the beginning, and then decline after about a year. After 2.5 years, I had a boost again, this time was also treated with cortisone. Since then I’m free of push, so now about 2 years. I can only say that I have now come from 3000 mg to 1000 mg Salofalk, so instead of 6 tablets 2 tablets. In the meantime, I was struggling with joint pain, but I practice a manual job, am a woman and I am almost 50 years old. No rheumatism. I am satisfied with Salofalk so far, and have good blood levels, general well. However, possible side effects could just be the joint pain, then sweating (easy, but I am also in the change of years) and weight gain … but not blatant. But at the same time in the last 4 years I found out what I can not eat or drink before anything else, that helps me very well, and the two colonoscopies each after the episodes were also so that I may hope, both times no inflammation. I do not know now whether I have a mild colitis and how I should evaluate all this exactly, but I believe that Salofalk despite the disadvantages is a good drug that also helps well with a lighter colitis, meanwhile I can eat a lot again, and I’m still free of complaints. as I said, I rely above all on my own diet, in which I repeatedly relieve the intestines for days of meat, milk and other things that do not get him. I would like to know more about my illness, … maybe my contribution will help, I hope so and keep my fingers crossed for all concerned. Can be bad, this disease.

  7. Andrew B. Williams says:
    4.0 rating

    Salofalk for Ulcerative colitis

    It took 3-4 months for it to have an effect – as well as an adverse effect of azathioprine. The following symptoms I have identified for me as a side effect of the drug: – joint pain, mainly in the leg and ankles – sleep disorders (very long sleep phase, sometimes after about an hour so wide awake that falling asleep only a few hours later is possible) – sporadic itching – Loss of appetite – often impotent – wounds heal bad It is of course also possible that these side effects are related to the simultaneous intake of Salofalk. Before I took the aza, I had taken the saolfalk together with betnesol and prednisolone, but there had been no improvement in the intestinal mucosa. The side effects as described above were not available. There was an acne known as cortisone preparations, which has now largely disappeared. Since the intestine has calmed down well now, I will try to sell Salofalk as a next step. The Azathioprin -so my doctor- I should take two more years.

  8. Karen D. Montes says:
    3.0 rating

    Salofalk for Morbus crohn

    Vomiting, fever, nausea, pain

    Side effects: Nausea
  9. Frank J. Boynton says:
    3.0 rating

    Salofalk for Ulcerative colitis

    Joint pain, especially in the arms and legs. Muscle pain, itching, fatigue, nausea, general feeling of being sick, especially in the evening at rest. When taking Salofalk alone, no problems

    Side effects: Itching; Joint pain; Fatigue; Nausea
  10. Charles B. Prom says:
    2.0 rating

    Salofalk for Ulcerative colitis

    Salofalk: Did not have an effect more than I took alone in conjunction with prednisolone they have worked better. Got dizzy spells, nausea and was knocked off. Prednisolone. She helped a lot but then had to drop off but took a toe and got acne. Highest dose was 80mg!

  11. Karen D. Williams says:
    3.0 rating

    Salofalk for Ulcerative colitis

    Without omep I have heartburn all the way down my throat, with Omep I’m tired, I’ve gained weight and I prefer to be alone

    Side effects: Fatigue; Increase in weight
  12. Victoria S. Drayton says:
    3.5 rating

    Salofalk for Ulcerative colitis

    In the fall of 2005, ulcerative colitis was diagnosed. After a few trials, I was discontinued with Salofalk 500 mg (6 tablets) and Budenofalk 3 mg (2 tablets). About 2 years ago the joint pain started and since then I take Tramadol 100 mg, At the moment 2 to 4 tablets and I am not pain free. Side effects I feel are: hair loss, fatigue, moody / aggressive. Despite the medication, it always comes back to a boost. Now I am to be switched to MTX Hexal 15 mg. Somehow I do not feel good about it. But the hope to finally be pain free again, can overcome the fear.

    Side effects: Fatigue; Hair loss
  13. Hazel M. Wagner says:
    4.0 rating

    Salofalk for Ulcerative colitis

    Currently have a colitis ulcerative colitis (moderate proctitis). The recommended drug after hospitalization was 3,000 mg Salofalk tablets (3×2 500 mg tablets) and Entrocort enema for 8 weeks. They showed no effect. The inflammation went on. Side effects: extreme fatigue, hair loss, dizziness, weight loss, difficulty concentrating After re-hospitalization, a cortisone preparation (Colifarm foam) was given for 3 weeks and Salofalk suppositories 3×1 500 mg daily. This treatment was successful. The bloody slimy diarrhea could be stopped. Side effects of Salofalk suppositories after about 2 months: persistent hair loss, tiredness, abdominal pain, listlessness

    Side effects: Fatigue; Hair loss; Dizziness