What Side Effects Can Risperidone Have?
Below you will find the most important information about possible known side effects of risperidone.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).
Very common side effects:
Parkinson’s-like tremors, headache, insomnia.
Common side effects:
Blood prolactin increase in value, weight gain, rapid heart rate, restlessness, dizziness, tremor, moodiness, drowsiness, twilight sleep, listlessness, involuntary movements, blurred vision, difficulty breathing, nosebleeds, cough, stuffy nose, throat and Laryngeal pain, vomiting, diarrhea, constipation, nausea, abdominal pain, indigestion, dry mouth, stomach upset, enuresis, skin rash, redness, joint pain, back pain, limb pain, increased appetite, decreased appetite, pneumonia, flu, bronchitis, upper respiratory tract infection, urinary tract infection, febrile attack, Fatigue, water retention in the arms and legs, weakness, chest pain, anxiety, excitement, sleep disorders.
Uncommon side effects:
ECG changes (eg, QT prolongation), blood sugar increase, blood enzyme elevation (transaminases), blood count changes (white blood cell reduction, eosinophils increased, platelet deficiency), hemoglobin lowering , Increased blood creatine phosphokinase, cardiac arrhythmia (AV block, thigh block, atrial fibrillation, sinus bradycardia), palpitations, anemia, lack of response to stimuli, loss of consciousness, fainting, loss of consciousness, brain dysfunction, transient circulatory disorder in the brain, speech disorder, attention deficit disorder, increased need for sleep, postural vertigo , Balance disorder, movement delay, speech disorder, misdirected movements, pain insensitivity, conjunctivitis, redness of the eye, ocular discharge, eye swelling, dry eye, increased tear secretion, photophobia, earache, tinnitus, wheezing, pneumonia (by inhalation of N pulmonary congestion, respiratory dysfunction, lung rattling, airway obstruction, voice disturbance, dysphagia, fecal incontinence, fecal obstruction, urinary retention, urinary incontinence, urinary flow, facial swelling, skin lesions, skin disorders, itching, acne, discoloration of the skin, alopecia, flaky dermatitis, dry skin, excessive corneal formation, Muscular weakness, muscle pain, neck pain, joint swelling, postural disorders, limb stiffness, chest muscle pain, refusal to eat, increased thirst, sinusitis, viral infection, ear infection, tonsillitis, dermatitis, otitis media, eye infection, local infection, skin inflammation, respiratory infection, cystitis, fungal nail infection, low blood pressure, Drop in blood pressure with change of body position, facial flushing, facial swelling, gait disturbance, changes in mood, heaviness, flu-like illness, thirst , Chest pain, chills, hypersensitivity, menstrual period, sexual dysfunction, erectile dysfunction, ejaculation disorder, morbid milk flow, breast swelling, menstrual disorder, vaginal discharge, confusion, over exacerbation, libido reduction, apathy, nervousness.
Rare side effects:
body temperature decline, granulocyte deficiency, neuroleptic malignant syndrome, diabetic coma, brain disease, circulatory disorder in the brain, movement disorders, visual acuity reduction, eye rolling, cataracts, sleep pauses (sleep apnea syndrome), panting, intestinal obstruction, Pancreatitis, lip swelling, lip inflammation, dandruff, muscle dissolution, excessive secretion of antidiuretic hormone (ADH), otitis media (chronic), general body swelling, body temperature too low, drug withdrawal symptoms, feeling cold (arms, hands, feet), drug hypersensitivity, jaundice. !! !!
Very rare side effects:
Body hyperacidity (diabetic).
Side effects of unknown frequency:
granulocyte deficiency, overhydration of the body, allergic reaction, penile rigidity, venous obstruction (also pulmonary embolism).
There may be symptoms of Parkinson’s disease such as twitching and tics, passive muscular resistance (rigor), severe tremor (tremor), increased salivation, inability to sit still (akathisia). These side effects are usually minor. However, if they are strong, they may be counteracted by dose reduction or by means of Parkinson’s disease treatment
What interactions does Risperidone show?
Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).
Concomitant therapy with tricyclic or tetracyclic antidepressants or with beta-blockers may result in a mutual enhancement of effect. In addition, the risk of heartbeat (tachycardia) is increased.
Selective serotonin reuptake inhibitors Fluoxetine and Paroxetine may increase the effect of risperidone.
Enzyme inducers such as barbiturates or carbamazepine can accelerate the breakdown of the neuroleptic.
Risperidone enhances the effects of alcohol, benzodiazepines, sedatives, anticholinergics, hypotensive agents (such as prazosin) and anesthetics.
Before an operation, the anesthetist must be informed about risperidone therapy.
Concurrent use of dopamine receptor agonists to treat Parkinson’s disease attenuates their effects.