The following provides information on contraindications to the use of ropinirole in general, pregnancy & breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should Ropinirol not be used?
Apart from the general prohibition of treatment for hypersensitivity to ropinirole and severe liver dysfunction, the drug may be used in different ways depending on the area of application:
The active substance must not be used in
- Patients with a hormone-producing adrenal tumor (pheochromocytoma)
- Past allergic reactions to psychoactive drugs such as neuroleptics such as fever, loss of consciousness, shock or heart failure.
Only after careful medical benefit-risk consideration and with caution may ropinirole be used in
- severe cardiovascular disease
- Psychosis (misunderstanding of reality, delusions)
- Use of levodopa because low blood pressure caused by it may continue to fall
- Promote agility through MAO inhibitors such as selegiline because their dose may need to be changed by the doctor.
The drug should not be used in severe renal impairment (creatinine clearance less than 30 milliliters / minute).
In addition, ropinirole should not be used to treat movement disorders and compulsive movements caused by neuroleptics. Also a Restless Legs Syndrome due to renal dysfunction, an iron deficiency anemia or pregnancy should not be treated with the drug.
Only after careful medical benefit-risk consideration and with caution ropinirole may be used in < ul>
- moderate hepatic impairment due to possible increased side effects
- severe cardiovascular disease (especially coronary heart disease) because of the risk of low blood pressure.
During treatment with ropinirole, signs of restless legs syndrome may be worsening: in the form of temporal progression of symptoms during the day or re-onset of symptoms in the early morning. If this happens, the doctor should reconsider the treatment and consider adjusting the dose or discontinuing treatment.
What should you watch out for during pregnancy and lactation?
During pregnancy and lactation the active substance must not be taken.
What should be considered in children?
Children under the age of 18 may not receive the active substance.
Warnings and Precautions
- During therapy, extreme daytime fatigue with sudden falling asleep may occur in rare cases.
- If the medication is discontinued, Parkinson’s requires the doctor to adjust the dose of other medicines to keep the symptoms of Parkinson’s disease under control.
- Treatment should be changed if pathological gambling addiction, sexual desire, compulsive spending or shopping, binge eating, and eating habits occur.
- Reactivity may be affected by the active substance.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.