About Requip

4.0 rating based on 16 ratings
Rating: 3.8 Reviews: 16
About Requip

Ropinirole may be given as a single agent at the onset of Parkinson’s disease or later, as the disease progresses, in combination with levodopa.

What is the purpose of this ingredient?

  • Alleviate symptoms of Parkinson’s disease
  • Treat the condition of restless legs
  • Control muscle twitching

This is how Ropinirol works

Below you will learn more about the fields of application and the mode of action of ropinirole.
Please also read the information on the drug groups dopamine receptor agonists, Parkinson’s agents, to which the active ingredient ropinirole belongs.

Application of the active substance ropinirole

Ropinirole may be given as a single agent at the onset of Parkinson’s disease or later, as the disease progresses, in combination with levodopa.

The active substance is also approved for the treatment of Restless Legs Syndrome. Patients feel an uncontrollable urge to move at night, often accompanied by muscle twitching and shooting pains. Here, as in Parkinson’s disease, a dopamine deficiency in the brain could underlie why the complaints on the dopamine receptor agonist ropinirole respond very well.

The active ingredient has to be taken for a long time in order to permanently stimulate the brain cells and alleviate the symptoms mentioned.

For the following application areas of Ropinirol , in-depth information is available:

  • Parkinson’s disease

Mode of action of ropinirole

Ropinirole is one of the dopamine receptor agonists as well as the group of agents for the treatment of Parkinson’s disease.

Like pramipexole, ropinirole binds preferentially to D3 receptors that reside on the brain cells. As a result, Parkinson’s patients can better implement and coordinate their movements. In order to additionally increase the mobility of patients in Parkinson’s disease, the Parkinson’s drug Levodopa is usually prescribed at the same time.

In restless legs syndrome, ropinirole inhibits abnormal nerve activity in the limbs.

Potential Requip side effects may include:

Effect
Percentage
29%
21%
14%

Requip used to treat the following diseases:

Disease
Percentage
93%
  1. Gerald F. Campos says:
    3.5 rating

    Requip for Parkinson's disease

    I started with 8mg of ropinirole and should gradually increase by 2mg every 14 days to 16mg. With each increase i had nausea and dizziness. Very dry mouth, now i am already at 20mg and must increase up to 24mg. My doctor says it takes time to get used to it. It was added that I sleep very badly at night and my body trembled on the whole loaf. Conclusion L-dopa comes to it. 125mg.

    Side effects: Dizziness; Nausea
  2. Kelley A. Herbert says:
    3.5 rating

    Requip for Parkinson's disease; Rls

    I have had good experiences with these medications. Side effect was dry mouth, otherwise I had none.

  3. Norma D. Wold says:
    3.0 rating

    Requip for Rls

    strong weight gain, itching, joint stiffness, in the morning 1-2 hours until you are clear in the head, otherwise very good sleep.

    Side effects: Increase in weight; Dizziness
  4. Rebecca J. Dempsey says:
    4.5 rating

    Requip for Rls

    i have rls since i am child. then in spurts over several years, then annually. These relapses annually are now accompanied by an aggravation of the symptoms. but I have had the symptoms daily for about 10 years. I started with 0.25. I am now at 2 x 0.5 in the evening. have since slept through the first time (despite the cold and 1 paracetamol). However, I am of the opinion that a dosage should go on throughout the day. It is true that ropinirole works badly when the fidgeting has just begun. so I take it as soon as I sit down in the evening. During the day I can still get up when these symptoms come. However, I had a push now with aggravation of the symptoms. means: pain in the legs no longer only at night in peace, but also during the day. probably as a consequence of the constant movements at night. but unfortunately there is only ropinirole retard from 2.0. I would need it now at 1.0.

    Side effects: Increase in weight
  5. Beatrice D. Jackson says:
    4.0 rating

    Requip for Rls

    Initially I took 0.5 mg ropinirole before going to sleep, after about 4 months I had to go up to 1 mg. Effect is great and I am virtually without discomfort. But I often suffered from nausea, otherwise no side effects … I thought. Since the beginning of the year I have gained about 6 kg without eating anything else. I did not associate this with ropinirole because the weight gain was so slow. But it must be related, especially since I read here that was the case with others.

    Side effects: Increase in weight; Nausea
  6. Joanne J. Wylie says:
    3.5 rating

    Requip for Rls

    At sifrol, it went quite well in the beginning, I was thrilled only after and stole strong fatigue, depresions and violent mood swings. after about two years, however, I had reached the highest dose, although the manufacturer stated that no dependency or increase in the dose is provided. with requip and ropinirole it is similar only because I reached the highest dose already after about 6 months. Among the two drugs, I found that my eyes have become extremely bad.

    Side effects: Fatigue
  7. Elizabeth G. Wright says:
    3.0 rating

    Requip for Rls

    I have to take the medication 2 hours before going to bed. Since I am very tired of it, the evening is not a joy for me, I just want to sleep. I’m a little sick of it and I have to constantly push open.

    Side effects: Fatigue; Nausea
  8. Betty T. West says:
    4.5 rating

    Requip for Rls

    Hello, take ropinirole for some time now and the effect diminishes. The dosage must repeatedly increase and my doctor is rock firmly convinced that the so-called Augmentation effect does not occur in the dopaminergist. It follows that my symptoms have become significantly worse within a year. But he also does not consider this possible, would not correspond to the course of the disease !? Besides, the pills make me very tired. Half an hour after taking it I have to go to bed because I’m tired, I have to vomit often. The symptoms occur earlier in the evening and sometimes I wake up (despite 12 hours duration!) In the morning at 6 in the morning because of the legs! I’m only 26 years old and I wonder where that ends! I also find no clever doctor, mine does not listen to me and has no understanding of my fear. Another, also specialized in RLS told me only, he thinks he understood what the disease but he can not help me ….. Knows a good doctor in the Rhein-Main area? Do you have similar experiences with RLS?

    Side effects: Fatigue
  9. Shirley W. Searle says:
    4.0 rating

    Requip for Rls

    I get other medications because of my RLS. Hydromorphone 80mg, Lyrica 600mg, Ariclaim 60mg and Amitriptyline 50mg. In addition to my depression and anxiety 100mg Sertraline, Lorazepam 7.5mg leg, Ropinirole is crept in with 2mg for 2 weeks, then 4mg for 2w, etc. to 16mg or ifs helps … was the neurologist’s statement. Am now at 6 mg and do not really notice any improvement in leg movements. A good doctor in the Rhine-Main area is an anesthetist and pain therapist in Hofheim. Dr. Ferlemann He wants to hear clear complaints what is really, where the pain, what has already been checked everything and tried and then he tells you what he thinks is right for you. But you can decide many things yourself and ask questions without any problems. He is also ready to throw a concept over it because it does not work and does not leave you alone for 3 months with the drug. In the beginning I was partly there every 2-3 days .. Has someone similar experiences, with the ropinirole or with the other drugs.

    Side effects: No side effects
  10. Juliet M. Farrington says:
    3.0 rating

    Requip for Rls

    Ropinirole is a very well-tolerated remedy for restless legs. Side effects are almost non-existent.

    Side effects: No side effects
  11. Shayna M. Machado says:
    4.0 rating

    Requip for Rls

    I have not taken Ropinirol for a long time, it was an attempt to see if it helps. And it does! So about 20 minutes before going to bed, I take 1 tablet. If I’m lying down, I’ll only need to tense up my (left) leg two to four times and let go, then I can fall asleep. Rarely do I have to take in the afternoon, but at night I continue my usual dosage. I hope it will help for a long time. That’s also the reason for my 10-point rating. 14.11.10 Moni B. from C.

    Side effects: No side effects
  12. Robert P. Cole says:
    3.5 rating

    Requip for Parkinson's disease

    I’m 62 years old and male. My neurologist has M.P. By means of a data-scan examination in Nov, 2010, I also found the MRI confirmed findings: Stroke in the Ponds. In May 2011, I was to the REHA in the Schmieder-Kliniken in Gailingen with moderate success. Since then I have been registered as incapacitated for work. As a drug with the disturbing side effect (permanent dizziness and balance disorders) I suspect the Azilect. I want my neurologist on 12.03. ask for alternatives.

    Side effects: Dizziness
  13. Tracey R. Westerman says:
    4.0 rating

    Requip for Rls

    Requip retard, … malaise. Lyrica, …………. dizziness. Tramadol ……. discomfort, constipation. Sertraline ….. dizziness (at the beginning)

    Side effects: Dizziness
  14. Mary R. Ferebee says:
    4.5 rating

    Requip for Rls

    I have suffered from RLS since childhood and did not know until 3 years ago that there would be a medical treatment for it. I entrusted myself to a neurologist who medicated me! I take Ropinirol from ABZ 3,5mg! (Starting with daily 1.0mg, then a few hours later 1.5mg and just before going to sleep 2.0mg) I tolerate so far quite well, sometimes there are severe nausea and circulatory breakdowns, I had to accept already, but that is relative Rare! However, there are still days when I could go crazy because I still have extremely strong restless legs / arms despite taking the medication. I noticed when the weather changes from warm to cold or vice versa, I suffer extremely! The other day I’ve read about a long-term acupuncture, the sufferers have had good experiences and should be comfortable. I will also undergo this acupuncture after consultation with my neurologist, and then report here whether I too will be symptom-free in the future. But I also like to take other advice. I wish all the better and especially calm legs / arms LG Anja;)

    Side effects: Nausea
  15. Janice J. Cooper says:
    5.0 rating

    Requip for Rls

    Ropinirole helps very well before the symptoms start. I take 6 mg ropinirole at around 20:30. If I take it before I start fidgeting, then I have rest all night. But I miss the moment and I fidget, and then take the first Ropinirol, then it takes hours until I finally come to rest. A disgusting side effect for me is the nausea that sometimes lasts up to 3 hours. I always have the feeling that the pills have slipped back into the esophagus and thus cause a gagging sensation. Dizzy is only from time to time. I can recommend Ropinirol.

    Side effects: Dizziness; Nausea
  16. Mary D. Lane says:
    3.0 rating

    Requip for Rls

    I have been taking 0.5 mg ropinirole at bedtime for 4 weeks. The effect is great! Before I took Levopar 125 mg for a few months, but then the efficacy was very fast and in the end it had no effect at all. The only side effect I feel is nausea. But it is getting better.

    Side effects: Nausea