The following is information on contraindications to the use of propranolol in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should Propranolol not be used?
propranolol should not be used in case of hypersensitivity to the active substance or other beta-blockers as well as in heart failure, bradycardia (resting heart rate at baseline below 50 beats per minute) and low blood pressure (hypotension).
The application is ruled out as well with a cardiovascular shock and serious illness of the conduction system of the heart (such as AV block II. Or III. Degree, sinus node syndrome).
The active substance should not be used in severe circulatory disorders of the arms and legs. The same applies to hypersensitivity of the bronchial system (such as asthma).
Propranolol should not be combined with MAO inhibitors for depression. Even with metabolic acidosis (acidosis) the application is prohibited.
Only with caution and strict medical supervision propranolol may be used in low conduction disturbances in the heart (AV block, first degree) in Diabetes (diabetes mellitus) with widely fluctuating blood glucose values or after prolonged strict fasting. Even heavy physical stress, pregnancy and lactation as well as impaired kidney or liver function require special medical care.
This medical care is required in patients with pheochromocytoma as well as psoriasis (psoriasis), even if this has occurred only when a family member. The same applies to the use of the drug, if ever severe hypersensitivity reactions to a drug have occurred.
What should you watch out for during pregnancy and lactation?
Propranolol should only be used during pregnancy in urgent cases. It can come with the unborn child to the growth delay. In addition premature labor can occur.
The drug should be discontinued 48 to 72 hours before delivery under medical supervision.
The active substance passes into breast milk. Infants should therefore be under medical supervision while breast-feeding.
What should be considered in children?
Propranolol should not be used in children.
Warnings and Precautions
- Kidney function and liver function should be monitored regularly during treatment with the drug.
- Contact lens wearers should be aware of the lacrimation that may be reduced by the drug.
- Diabetes requires regular blood glucose monitoring.
- The drug may cause allergic reactions in isolated cases.
- Before anesthesia, the anesthetist should be informed about the treatment with the drug.
- Treatment with the drug should not be stopped abruptly, but should be “skipped” at a reduced dosage.
- The drug can affect your ability to react in ways that make driving and operating machinery dangerous.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.