About Propranolol

2.5 rating based on 11 ratings
Rating: 2.5 Reviews: 11
About Propranolol

Propranolol lowers blood pressure in high blood pressure and coronary heart disease.

What is the purpose of this ingredient?

  • Slow heartbeat
  • Lower blood pressure
  • To mitigate the effects of hyperthyroidism on the heart
  • Reduce tremors without known cause
  • Prevent migraine attacks
  • Relieve anxiety
  • Prevent recurrent heart attacks

This is how Propranolol works

Below you will learn more about the fields of application and the mode of action of propranolol.
Please also read the information on the drug groups beta-blockers, antihypertensives, to which the drug propranolol belongs.

Applications of the active substance propranolol

Propranolol lowers blood pressure in high blood pressure and coronary heart disease.

The drug slows down and rhythmizes the heartbeats in rapid cardiac arrhythmias. Cardiac arrhythmias triggered by exercise, narcosis or sympathomimetics (a group of nervous system-stimulating drugs) can also be treated with propranolol. In addition, propranolol is used in cardiac conditions with no apparent organic cause, such as hyperkinetic heart syndrome. In addition, by eliminating the risk factor of high blood pressure, the active substance can be used to prevent a renewed myocardial infarction as well as attacks of the heart ganglia (angina pectoris). Propranolol can balance the effects of hyperthyroidism on the heart.

The active substance is used in the preventive treatment of migraine, trembling with no known cause (essential tremor) and anxiety disorders.

For the following application areas of Propranolol , in-depth information is available:

  • migraine
  • Hypertension
  • arrhythmia
  • infarction
  • anxiety disorders
  • hyperthyroidism
  • heart failure
  • Angina pectoris
  • Cardiovascular Disease

Action of Propranolol

Propranolol is a so-called non-selective, fat-soluble beta-blocker that works on both beta-1 and beta-2 receptors (not just the heart). Propranolol binds preferentially at special binding sites (receptors) of the sympathetic fibers of the vegetative nervous system. The active ingredient displaces the body’s own messenger substances from the receptor, which want to exert an activating function. This suppresses this activation.

With beta-1 receptors in the heart, propranolol lowers the number of heart beats (frequency) and reduces cardiac muscle tension. In addition, the transmission of electrical impulses to the conduction system of the heart is slowed down. Thus, the heart is “calmed down” and thus relieved of too high stress activity.

At beta-1 receptors in the kidneys, propranolol cushions the release of the blood pressure enhancing hormone renin. So the blood pressure is lowered.

In blood vessels that have both beta-1 receptors and beta-2 receptors, propranolol causes a narrowing of vessel diameter. As a result, the vessels, which are too dilated in a migraine, again narrows to a normal level.

The way in which propranolol works in anxiety disorders and trembling without an organic cause has not been proven yet.

Propranolol is absorbed relatively quickly and almost completely from the intestine. However, before it is distributed through the bloodstream in the body and reaches the heart, about two-thirds of the amount of active substance in the liver is broken down (so-called “first-pass effect”). The excretion occurs after metabolism in the liver largely through the kidneys. In case of a liver dysfunction or renal dysfunction, a prolonged effect must therefore be expected and, if necessary, the dosage should be adjusted.

Potential Propranolol side effects may include:

Effect
Percentage

22%

22%

Propranolol used to treat the following diseases:

Disease
Percentage

39%

28%

  1. Lawrence M. Hadley says:
    3.5 rating

    Propranolol for Tremor

    Strengthening of the tremor and muscle pain in the shoulders, the cervical spine

    Side effects: Muscle aches
  2. Deborah S. West says:
    1.5 rating

    Propranolol for Migraine

    Whether Nebenwikung or not, I could observe an extreme sense of relaxation. Besides, I was very very cheerful

  3. Margaret S. Byrne says:
    2.5 rating

    Weight gain, hair loss, aggression.

    Side effects: Increase in weight
  4. Susanne T. Lord says:
    3.0 rating

    By Carbimazole significant weight gain, which is more related to the hyperthyroidism and with the eating habits that one learns during the hyperfunction and usually can be difficult to take off, if one is reinstated by the drug.

    Side effects: Increase in weight
  5. Franklin F. Broughton says:
    3.5 rating

    Propranolol for Tremor

    The Alprazolam acts after about 20-30min very reliable and takes me in need the fear very well. Initially with a dose of 3mg and now it is 1mg. Before that, I had tried Lorazepam, which showed no effect on me. The propranolol shows no side effects. The tremor is in spite of the intake (3x daily 40mg) available and felt only slightly muted.

    Side effects: Fatigue
  6. Jeff S. Eddy says:
    1.0 rating

    Nightmares, tiredness.

    Side effects: Fatigue
  7. Pamela W. Maly says:
    2.5 rating

    fatigue

    Side effects: Fatigue
  8. Michele M. Lockhart says:
    4.0 rating

    Muscle pain in the area of the lateral spine and the left side of the hws

    Side effects: Muscle aches
  9. Ronald B. Howard says:
    3.5 rating

    Propranolol for Tremor

    The drug Edronax I take now for six days. This was due to an extreme drive weakness and constant fatigue, along with a great limitation of short-term memory. All this after successful treatment of a Panick disturbance with accompanying depression. Side effects of Edronax so far: Sleep disorder, which is unacceptable if not decay as a side effect for me and probably then leads to discontinuation of the drug! Furthermore, the following are justifiable side effects: occasionally palpitations, sweating, restlessness and disturbance of the sexual life. I got Sertraline for the panic disorder. Unfortunately, the drive increase described in all antidepressants did not materialize here. The panic disorder was, however, now almost completely cured. The only side effects here were the strong trembling of the hands began and sexual intercourse with my wife was almost only possible with appropriate drugs to increase the erection. The tremor was successfully corrected by my psychiatrist with the propranolol once a day 10mg. With the propranolol I never had any side effects. There were never any side effects with drugs that increased recovery. I wish for the pharmaceutical industry, finally, a Antriebssteigerndes- and mood-enhancing drug, which also keeps what it promises! After 2.5 years Sertraline daily 200mg! I have noticed by a mood brightening and drive increase if I’m honestly nothing. The panic disorder, however, has almost completely eliminated it so far.

    Side effects: Unrest