About Propofol

3.5 rating based on 32 ratings
Rating: 3.3 Reviews: 32
About Propofol

Propofol is used as a short-acting substance in general anesthesia. It is used to initiate and maintain the mindset and sedation of patients undergoing intensive ventilation or undergoing special examinations or operations.

What is the purpose of this ingredient?

  • Align brain cells in the cerebral cortex
  • hinder communication between brain parts
  • Turn off consciousness

This is how Propofol works

Below you will learn more about the fields of application and the mode of action of Propofol.
Please also read the information on the drug groups to which the drug Propofol belongs.

Applications of the active substance Propofol

Propofol is used as a short-acting substance in general anesthesia. It is used to initiate and maintain the mindset and sedation of patients undergoing intensive ventilation or undergoing special examinations or operations.

Depending on the field of application, Propofol is used alone or together with analgesics of local or general effect.

Propofol can only act on the bloodstream and is therefore given solely as an injection or into the vein.

For the following application areas of Propofol , in-depth information is available:

Action of Propofol

Propofol is used in anesthesia surgery. However, it has no analgesic and no muscle-relaxing effect. Propofol must therefore be combined with analgesics and, if necessary, with muscle relaxants for painful procedures.

The most likely mechanism of action today is thought to be that propofol massively alters the basic activity of the cerebral cortex. The drug appears to interfere with communication between different brain areas by “matching” a large number of nerve cells (neurons). This synchronization prevents signals from being sent from the cerebral cortex to other brain regions. This ultimately breaks down information processing in the cortex, which could be the key to the controlled loss of consciousness.

Propofol acts quickly and quickly and is available only in the form of syringes. Already 10 to 20 seconds after the injection the effect comes in and lasts with only one application only eight to nine minutes. The effect can be sustained by continuous infusion or repeated dosing with smaller doses.

Potential Propofol side effects may include:

Propofol used to treat the following diseases:

Disease
Percentage
24%
4%
  1. Gladys L. Benedict says:
    4.0 rating

    Propofol for Colonoscopy

    For a colonoscopy, I got Propofol. After waking up you should actually be just a little bit hazy. But after anesthesia I spent 6 hours in a kind of delirium. The worst nausea I’ve ever had, vomiting, fantasizing, rolling my eyes in all directions, barely responsive. After approx. 6 hrs. thank God for all that.

    Side effects: Hallucinations; Nausea; Vomit
  2. Mary R. Lavoie says:
    3.0 rating

    In Prepacol due to the nasty and salty taste, vomiting more often. I could not pay much with that, so the colonoscopy could not take place. Propofol: very good drug with deep calming. Excellent for endoscopy. No side effects with me. Novalgin suppositories: Mild rectal use, very well tolerated. Side effects with me none available.

    Side effects: Vomit
  3. Eloisa W. Nantz says:
    4.5 rating

    Propofol for Endoscopy

    In the course of a gastroscopy (gastroscopy) in front of which I shivered days before, I was injected, after consultation with the doctor Propofol. I made a conscious decision against Dormicum, as I was able to observe quite a few reactions to that drug as part of my work as a nurse. Therefore, I was aware that due to the phenomenon of retrograde amnesia, many patients consciously experience examinations, but in no way remember them. I wanted to avoid this. So Propofol had to come here. The doctor injected me, after all preparations were made for mirroring, 220mg Diprivan successively divided into 3 thirds. After giving the first part, I also felt the nice tingling sensation on the whole body, which I did not feel uncomfortable at all. At the second third, my eyes became heavy, but I was still fully conscious. While I was wondering if I would really fall asleep, I was injected with the third third. I think I did not finish my sentence. Anyway, I can remember from that moment on absolutely NOTHING. When I was awakened after the examination, I could not believe it. I asked the nurse, if I had choked, during the examination, what she confirmed to me. And as much as I try to remember it or details … nothing. I have consciously perceived absolutely nothing. Can only remember that I dreamed just before I was awakened. So off to the recovery room. I was told that I have to sleep for another hour. Booaahh, painfully, I’m still fit, I thought to myself, stared at the curtain for about 15 minutes and watched the nursing staff working. However, when I looked at the clock, 1 hour had passed 15 minutes. No idea where this one hour left …. I am still really sure that I have not slept. Somehow funny when suddenly one hour is erased from memory. My result: At any time, however, without panic and very relaxed. The most unpleasant part of the procedure was the xylocaine spray, which made swallowing quite difficult for me. Otherwise: no sore throat, no nausea, nothing! So to all who still have it in front: do not panic on the Titanic. Is really easy going

    Side effects: Memory gaps
  4. Ronald C. Lewis says:
    4.5 rating

    Propofol for Endoscopy

    I can only recommend it . Since I could not imagine swallowing the tube with consciousness. Stood for me from the beginning, the investigation to do in short anesthesia. I was given midazolam 7.5mg iv. and Propofol 50mg administered iv. I can only remember that the doctor has injected me a clear liquid and I still thought to me funny why he sprayed me NACL ??? (I know that propofol is white) Then came this tingling sensation and the warmth of the whole body. The Doc still said to me now they are getting tired and I still said I know. After that I know nothing more. I have ADS and I also take medicines Medikinet Adult, of course I did not take it before gastroscopy, but felt the whole day as if I had taken it.

    Side effects: Memory gaps
  5. James D. Lee says:
    4.5 rating

    Propofol for Colonoscopy

    Have the colonoscopy today 220 mg i.v. Get Propofol. Before that 10mg Buscopan for reassurance, as well as 1.5 mg Dormicum according to the report. Had a big panic before the reflection. But when I got the propofol injected, I was within 5-10 seconds away. After about 3-5 seconds, the effect occurred. A whole tingling sensation on the body and a warmth which I found very pleasant, then I slept. I even remember that I had dreamed something beautiful 🙂 Can only recommend to anyone to Propofol in the colonoscopy can be spritzten. From the colonoscopy itself, I did not notice anything. However, I miss the memory of how I dressed? : D Otherwise I went to top, except for the stupid air that was still in the intestines, but for Propofol can not do anything. Had until tonight still many memory gaps although in my mind was very clear. Have just forgotten everything, a lot of what I said today ^ ^ When I woke up from the Propofol I said something confused that they should finally start because I have a bloody fear: PPP I can only recommend!

    Side effects: Memory gaps
  6. Jorge F. Hernandez says:
    3.0 rating

    Propofol for Colonoscopy

    got propofol for colonoscopy, at the injection I got dizzy and then I was gone. the only negative effect was that they apparently did not give me enough; I woke up shortly before the bow mirroring, which unfortunately was not very pleasant … otherwise no side effects.

    Side effects: Dizziness
  7. Beverly J. McGuire says:
    3.5 rating

    fertile, when taking it in gastroscopy, etc. breath depression, severe dizziness, cramps, pain and strong burning in the chest …

  8. Tamera J. Pond says:
    5.0 rating

    Propofol for Surgery

    I had 2 anesthesia so far. The first without, the second with propofol. In contrast to the first one, it was NOT bad for me this time, was there in the recovery room, wide awake. After the first one I was sick for 2 days and it took me tens of hours to come to some extent. Until now, 8 hours after the op, I still have very slight dizziness. Narcosis with Propofol = highly recommended for me.

    Side effects: Dizziness
  9. Bryan V. Saunders says:
    3.0 rating

    Propofol for Endoscopy

    I had an endoscopy 5 years ago without a syringe, never again! This time it was really pleasant, got 150mg i.v. fractionated under current pulse oximeter! I got the injection knows they pushed me the ring in the mouth. After that, I was really lying down and I was gone, woke up again had a nice short dream and had to sort everything again first so I knew what was SAche but that was fast and then I had only a little slow reaction. Have as before in the Prtacis then for 1 cTag driving prohibited. I would do the same again next time.

    Side effects: No side effects
  10. Melissa W. Sanders says:
    2.5 rating

    Propofol for Colonoscopy

    In 2000 in hospital on anesthesia induction (due to colonoscopy) with propofol respiratory arrest. The doctors have denied that this was due to Propofol. That I had a respiratory arrest right after the Propofolgabe (I still noticed that my body rears up, then it was dark) I only through a well-known nurse present, the doctors have downplayed this. (At that time I had the anesthesia report secretly copied, but there are only the drugs noted, nothing of the respiratory arrest) Through the discussion of Michael Jackson, I have now thought again and found this site. Maybe the doctors at Propofolgabe just have to be a bit more careful, or better not use anymore! Have always pointed to the possible incompatibility before surgery and something so far not experienced again.

    Side effects: No side effects
  11. Susan N. Beattie says:
    2.0 rating

    Use in gastroscopy after administration of 100mg for a gastroscopy after waking reduced responsiveness, hyperventilation, crying, short-term immobility

    Side effects: No side effects