About Promethazine

3.5 rating based on 61 ratings
Rating: 3.3 Reviews: 61
About Promethazine

Promethazine is used differently due to its diverse mode of action.

What is the purpose of this ingredient?

  • Restlessness and agitation as well as anxiety disorders in psychiatric disorders (psychoses) dampen
  • allergic reactions such as watery eyes, runny nose or asthma attacks with shortness of breath, rash, redness and itching of the skin and suppressing diarrhea in allergies
  • reduce nausea, vomiting, and sleep disturbances
  • Reduce anxiety and tension before surgery

How promethazine works

Below you will learn more about the fields of application and the mode of action of promethazine.
Please also read the information on the drug classes H1-antihistamines, neuroleptics, antiallergic drugs, to which the active ingredient promethazine belongs.

Areas of application of the active substance promethazine

Promethazine is used differently due to its diverse mode of action.

On the one hand, it is prescribed for allergic diseases (allergies) to suppress allergic reactions such as watery eyes, runny nose or asthma attacks with shortness of breath, rash, redness and itching of the skin as well as diarrhea.

On the other hand, promethazine is used for basic psychiatric disorders (psychoses), in particular for the relief of agitation and agitation or anxiety disorders. Promethazine can be administered in this context as a single agent or in combination with other drugs from the group of psychotropic drugs.

Promethazine’s soothing and calming action is also used for anesthesia preparation to relieve the patient of the fear of surgery.

Ultimately, the drug can also be used to treat nausea and vomiting or sleep disorders. However, for this purpose, less side-effect-rich therapeutic trials should be undertaken beforehand.

For the following application areas of Promethazine , in-depth information is available:

  • Nausea and vomiting
  • sleep
  • allergy
  • psychosis
  • anxiety disorders

How promethazine works

The active substance promethazine is a H 1 antihistamine with a strong soothing (sedative) effect. It is therefore mainly used as a means of treating allergies and as a sedative (sedative) for the relief of sleep disorders use.

The messenger histamine triggers the symptoms that occur in an allergy. Mostly it is inflammatory complaints (watery and itchy eyes, redness and itching of the skin, runny nose, but also diarrhea). Histamine is transported via the bloodstream to different regions of the body. Promethazine occupies the binding sites of the histamine (H1 receptors) in the body. As a result, the histamine can no longer develop its effect in the body and the allergic reactions remain. Promethazine also occupies the binding sites in the brain. This makes it reassuring and sleep-inducing.

Promethazine continues to be able to inhibit the effect of the body’s own messenger dopamine. Therefore, it is simultaneously assigned to the weakly effective neuroleptics. Due to its dopamine-inhibiting effect restlessness and anxiety disorders, as they often occur in connection with a psychosis, dampened.

Promethazine stimulates salivation and intestinal activity via its influence on the messenger acetylcholine, which is why it can be used effectively for nausea and vomiting.

Potential Promethazine side effects may include:

Promethazine used to treat the following diseases: