Prednisolone

3.5 rating based on 231 ratings
Rating: 3.5 Reviews: 231
Prednisolone

Prednisolone is available in many different dosage forms. These include tablets, capsules, infusion solutions and injection solutions for internal (systemic) injection. For local (local) use, also in combination with other active ingredients, suppositories, ointments, creams, pastes, gel preparations, tinctures, drops and solutions are available.

Prednisolone is used in tablet form or given directly into the bloodstream at

  • Balancing treatment (substitution therapy) of adrenocortical insufficiency (Addison’s disease) and anterior pituitary weakness (first-line means hydrocortisone and cortisone)
  • Stress states after long-term cortisone therapy
  • Inflammatory rheumatic diseases such as inflammation of all joints (chronic polyarthritis) and acute inflammatory processes on individual joints for pain relief and anti-inflammatory
  • Inflammation of blood vessels
  • Disease with connective tissue remodeling (collagenosis) such as lupus erythematosus (butterfly lichen) to delay disease progression
  • Bronchial and pulmonary diseases such as bronchial asthma and COPD (concomitant administration of bronchodilators) and pulmonary tissue disorders of various causes
  • Diseases of the upper respiratory tract such as severe forms of hay fever and allergic rhinitis after the therapeutic failure of glucocorticoids to inhale and -spray
  • acute narrowing of larynx or trachea (in pseudo-Krupp also as a suppository) or for the prevention of respiratory distress syndrome in preterm infants
  • Heart disease such as pericarditis (endocarditis), including those caused by rheumatic inflammation
  • blood diseases of various causes
  • Diseases of the nervous system
  • Infections like meningitis due to tuberculosis
  • Diseases of the kidneys, ureters, bladder or urethra.
  • diseases of the digestive tract as well as inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease
  • liver diseases
  • the treatment of blood cancer (leukemia) and lymph node cancer. However, prednisolone only has a soothing effect on the symptoms; the cause of the disease is not treated as a result. In addition, the active ingredient also prevents the vomiting caused by chemotherapy.

Local administration of prednisolone is either alone or in addition to in-house treatment with the active substance. Opportunities for such use are:

  • allergic and / or inflammatory skin diseases
  • Eye diseases such as dermal inflammation or inflammation of the middle eye skin.
  • Diseases of the teeth, gums and oral mucosa such as acute gingivitis, inflammation of the mouth and inflammation of the gum pockets
  • Inflammatory hemorrhoids, inflammation in the anal area or rectal inflammation.

What is the purpose of this ingredient?

  • Inhibit inflammation
  • relieve allergic reactions
  • Balance functional weakness of the adrenal cortex
  • to compensate for the lack of hormone production in the pituitary gland
  • relieve rheumatic diseases
  • relieve diseased remodeling of connective tissue
  • relieve transient acute inflammation on multiple joints
  • positively influence chronic inflammation
  • treat heart disease
  • Alleviate bronchial and lung diseases such as bronchial asthma
  • Mitigate lung tissue disorders of various causes
  • Prevent respiratory distress syndrome in premature babies
  • Alleviate laryngeal and tracheal narrowing (such as pseudo-Krupp)
  • to cure allergic and or inflammatory skin diseases
  • Alleviate hay fever and allergic rhinitis
  • support cancer treatment
  • treat blood disorders of various causes
  • Alleviate symptoms of malignant disease
  • Prevent vomiting by chemo and treat
  • Alleviate infectious diseases
  • Alleviate Nerve Disorders
  • combat eye inflammation
  • Affect diseases of the digestive tract and liver
  • Alleviate kidney and urinary tract disease
  • relieve inflammatory gastrointestinal diseases

This is how Prednisolone works

Below you will learn more about the fields of application and the mode of action of Prednisolone.
Please also read the information on the drug groups glucocorticoids, anti-inflammatories, to which the drug prednisolone belongs.

Applications of the active ingredient prednisolone

Prednisolone is available in many different dosage forms. These include tablets, capsules, infusion solutions and injection solutions for internal (systemic) injection. For local (local) use, also in combination with other active ingredients, suppositories, ointments, creams, pastes, gel preparations, tinctures, drops and solutions are available.

Prednisolone is used in tablet form or given directly into the bloodstream at

  • Balancing treatment (substitution therapy) of adrenocortical insufficiency (Addison’s disease) and anterior pituitary weakness (first-line means hydrocortisone and cortisone)
  • Stress states after long-term cortisone therapy
  • Inflammatory rheumatic diseases such as inflammation of all joints (chronic polyarthritis) and acute inflammatory processes on individual joints for pain relief and anti-inflammatory
  • Inflammation of blood vessels
  • Disease with connective tissue remodeling (collagenosis) such as lupus erythematosus (butterfly lichen) to delay disease progression
  • Bronchial and pulmonary diseases such as bronchial asthma and COPD (concomitant administration of bronchodilators) and pulmonary tissue disorders of various causes
  • Diseases of the upper respiratory tract such as severe forms of hay fever and allergic rhinitis after the therapeutic failure of glucocorticoids to inhale and -spray
  • acute narrowing of larynx or trachea (in pseudo-Krupp also as a suppository) or for the prevention of respiratory distress syndrome in preterm infants
  • Heart disease such as pericarditis (endocarditis), including those caused by rheumatic inflammation
  • blood diseases of various causes
  • Diseases of the nervous system
  • Infections like meningitis due to tuberculosis
  • Diseases of the kidneys, ureters, bladder or urethra.
  • diseases of the digestive tract as well as inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease
  • liver diseases
  • the treatment of blood cancer (leukemia) and lymph node cancer. However, prednisolone only has a soothing effect on the symptoms; the cause of the disease is not treated as a result. In addition, the active ingredient also prevents the vomiting caused by chemotherapy.

Local administration of prednisolone is either alone or in addition to in-house treatment with the active substance. Opportunities for such use are:

  • allergic and / or inflammatory skin diseases
  • Eye diseases such as dermal inflammation or inflammation of the middle eye skin.
  • Diseases of the teeth, gums and oral mucosa such as acute gingivitis, inflammation of the mouth and inflammation of the gum pockets
  • Inflammatory hemorrhoids, inflammation in the anal area or rectal inflammation.

For the following application areas of Prednisolone , in-depth information is available:

  • Psoriasis
  • eczema
  • inflammation
  • allergy
  • asthma
  • COPD
  • acute bronchitis
  • inflammatory rheumatic diseases
  • liver inflammation
  • Multiple sclerosis
  • cirrhosis
  • chronic inflammatory bowel disease
  • Cancer (general)
  • chronic bronchitis
  • tuberculosis
  • Inflammation of the oropharynx
  • conjunctivitis
  • eczema
  • itching
  • hair loss
  • arthritis
  • skin infections
  • respiratory diseases with mucus
  • pneumonia
  • Eye infections caused by bacteria
  • Cardiovascular Disease
  • graft rejection

Mode of action of Prednisolone

Prednisolone belongs to the drug group of glucocorticoids. It contains no fluorine in its molecule and is quite similar to the body’s hydrocortisone. However, the active ingredient is one of the weaker effective agents of glucocorticoids. Depending on the dose, prednisolone affects the metabolism of almost all tissues.

In case of failure or weakness of the adrenocortical function, there is a lack of endogenous hydrocortisone. Hydrocortisone is needed to regulate carbohydrate, protein and fat metabolism. Prednisolone, taken as a tablet

Potential Prednisolone side effects may include:

Prednisolone used to treat the following diseases:

  1. Mary B. Picard says:
    4.0 rating

    Prednisolone for Optic nerve inflammation

    My retrobulb neuritis started on Nov 14, and so far it is not completely gone. I first got 100 mags of prednisolone a day, then I would be pumped full of 1000mg on 3days at the hospital. You dismissed me with the words you do not need cortisone, which then immediately made negative, eyesight worse again and the side effects hammer: restlessness, tachycardia, rash, soreness, sweating, and distorted perception, oh and of course very, very heavy legs .A conclusive finding of the drawn nerve water is still outstanding, MRI Uunauffällig.Im February I have to go back to the KH, again all the investigations. But think there is nothing, only I would like to finally be able to see properly again!

    Side effects: Sweat; Skin rash; Unrest; Palpitations
  2. Juan T. Hung says:
    4.0 rating

    Prednisolone for Optic nerve inflammation

    Extreme side effects after switching from 5 x 1 g cortisol shock therapy iV for optic nerve inflammation. Afterwards, reduce from 225 g to 0 in 14 days. No sleep possible at the changeover, extreme mood swings (euphoria / nervous breakdown). Extreme motivation / urge to move. Walk around for hours with simultaneous physical exhaustion and high weight loss. Afterwards giant appetite (at first 8 kg lost in one week, then increased again in 2 weeks). Loss of taste (salt without taste, only greasy / sweet recognizable). tremendous joint pain in the knees in the middle of the night shortly before the end of the reaming. Feels like a vise. In sum, the most intense physical experience so far – and that really means something.

  3. Leroy J. Rivera says:
    3.5 rating

    Prednisolone for Thrombocytopenia

    I’ve been on Prednisolone for almost a year. Dosage at the moment 5mg (starting with 100mg). The decisive point is thrombocytopenia. My high-dose experience: sleep disorder, restlessness, rapid heartbeat, cold sweating, steroid acne, typical moon face, mood swings with depression, and those annoying cravings. Since about 20mg: formation of glaucoma (glaucoma) and increase in intraocular pressure about one hour after taking the drug. Pain in the foot, knee, hip, shoulder and finger joints (gradually … beginning with the knees). Increased formation of darkening (acne) about 3cm tall. With 5mg: cravings, sleep disturbance, restlessness and depression, as well as pain in the joints continues to exist. There was also a very peculiar and very penetrating smell in the Axelhölen … not two minutes after washing, the smell was back. (presumably it is in connection with L-thyroxine 50mg). It is also an uncontrollable change between being awake and being extremely tired again. Think this is due to the shut down immune system. As far as my experience with the drug.

  4. Jennifer M. Ferrara says:
    5.0 rating

    Prednisolone for Thrombocytopenia

    I had an autoimmune reaction after pregnancy, which was expressed as below 15,000 platelets. I got hematoma everywhere, and gum bleeding after brushing my teeth. I was then treated with a shock therapy. At the moment I am still taking 40mg of the drug and have to say that I am doing very well! I can concentrate much better and almost everything is easier than before. The drug pushes me right and I’m a lot more powerful than before. As a young mother that’s just right :-). Regular exercise and a healthy diet currently help me maintain my weight. Soon I only have to take 25 mg of cortisone and I’m curious to see if I can control myself like that or whether my increased mental control leaves me again (I hope not, because the feeling is awesome). The fact is that then the water retention disappear again and I look forward to it. So I can not report anything negative.

    Side effects: Euphoria; Water storages
  5. Heather J. Claussen says:
    3.5 rating

    Prednisolone for Arthrosis

    Lead fatigue, increased appetite, water retention, weight gain

  6. Robert C. Cahill says:
    1.5 rating

    Prednisolone for Inflammation

    I’m always tired! So definitely need afternoon nap

    Side effects: Fatigue
  7. Joan S. Martin says:
    5.0 rating

    Prednisolone for Inflammation

    with dose reduction, inflammation returns, thus suppressing it only for the duration of a high dose (50 to about 15 mg) upset stomach spleen complaints liver problems circulatory disorders in the legs weight gain due to water retention rash on my doctor’s face was urged to a daily dose below 10 mg because of the risk of diabetes (family history) advised

  8. Josephine S. Ashurst says:
    4.5 rating

    Prednisolone for Skin rash

    First 4 days 75mg, 4 days 50mg, 4 days 25mg At first I tolerated it quite well, but then came unbearable tachycardia, increased heart rate too. Even after reducing to 25 mg, my heart rate is constantly there. Pulse I feel all over. ..just awful. Am constantly nervous, inner restlessness, tremble, hot flashes and then again chills …. I prefer to live with the rash than to take this medis again. I just hope that this heart rate quickly ceases, that makes you crazy!

  9. William P. Golden says:
    2.5 rating

    Prednisolone for Skin rash

    Tired and tired

  10. Kerri D. Pineiro says:
    4.0 rating

    Prednisolone for Hives

    I have been taking up to 180 mg of prednisolone per day for over a year. During that year, I gained 20 kg, my skin cracked and I had a bad moon face. In acute episodes, it only partially helped.

  11. Alan J. Noll says:
    4.0 rating

    Prednisolone for Hives

    Have you been taking heartburn despite strict diet. Sleep problems that are getting worse as you crawl. I’m glad if I can sleep at night for two hours. Furthermore, I had the first few days of vision problems and shaky legs.

    Side effects: Sleeping problems
  12. Raquel P. Miller says:
    4.0 rating

    Prednisolone for Rheumatoid arthritis

    I take Prednisolone if I have an arthritis episode. I tolerate this drug very well, I do not notice any side effects. My driving force is boosted by prednisilone, the efficiency increases, the pain decreases. My treatment duration is 4 weeks – 10 mg are enough for me. Can really recommend this medicine, especially in rheumatoid diseases.

    Side effects: No side effects
  13. Kenneth A. Sneller says:
    3.0 rating

    Prednisolone for Pain (back)

    Extreme water retention! Hunger! Thin skin! But pain away!!

    Side effects: Water storages
  14. Donna J. Bailey says:
    4.5 rating

    Prednisolone for Bronchitis (acute)

    I got an unexpected severe bronchitis with an asthma attack …. unfortunately I may not cortisone because of my severe osteoporosis …… but with the agreement of my doctors I was allowed a shock therapy of 5 days a ’50 mg …… . because it could not be otherwise … not a thimble of air I could still breathe …. that was escalated …… this therapy has done me good … Without that, I would definitely have landed in the KH , I am grateful that my doctors have responded so … and I could stay home …. and have recovered well. Thanks to many dear nice children ……. with me …., to me … were present in thought ……. One thing I know. Of course I’ll die someday, too. But suffocate. That’s what I imagine terrible …….. The rest of the still missing to complete recovery. Are sun and love children around me. And laugh. Because laughing is healthy * G * lg Angelblack

    Side effects: No side effects
  15. John S. Harper says:
    4.5 rating

    Prednisolone for Copd

    Without the daily intake (morning and evening) I can not breathe. This coming Monday, it will be the third time to Chemnitz in the lung clinic.

    Side effects: Listlessness