Prednisolone

3.5 rating based on 232 ratings
Rating: 3.5 Reviews: 232
Prednisolone

Prednisolone is available in many different dosage forms. These include tablets, capsules, infusion solutions and injection solutions for internal (systemic) injection. For local (local) use, also in combination with other active ingredients, suppositories, ointments, creams, pastes, gel preparations, tinctures, drops and solutions are available.

Prednisolone is used in tablet form or given directly into the bloodstream at

  • Balancing treatment (substitution therapy) of adrenocortical insufficiency (Addison’s disease) and anterior pituitary weakness (first-line means hydrocortisone and cortisone)
  • Stress states after long-term cortisone therapy
  • Inflammatory rheumatic diseases such as inflammation of all joints (chronic polyarthritis) and acute inflammatory processes on individual joints for pain relief and anti-inflammatory
  • Inflammation of blood vessels
  • Disease with connective tissue remodeling (collagenosis) such as lupus erythematosus (butterfly lichen) to delay disease progression
  • Bronchial and pulmonary diseases such as bronchial asthma and COPD (concomitant administration of bronchodilators) and pulmonary tissue disorders of various causes
  • Diseases of the upper respiratory tract such as severe forms of hay fever and allergic rhinitis after the therapeutic failure of glucocorticoids to inhale and -spray
  • acute narrowing of larynx or trachea (in pseudo-Krupp also as a suppository) or for the prevention of respiratory distress syndrome in preterm infants
  • Heart disease such as pericarditis (endocarditis), including those caused by rheumatic inflammation
  • blood diseases of various causes
  • Diseases of the nervous system
  • Infections like meningitis due to tuberculosis
  • Diseases of the kidneys, ureters, bladder or urethra.
  • diseases of the digestive tract as well as inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease
  • liver diseases
  • the treatment of blood cancer (leukemia) and lymph node cancer. However, prednisolone only has a soothing effect on the symptoms; the cause of the disease is not treated as a result. In addition, the active ingredient also prevents the vomiting caused by chemotherapy.

Local administration of prednisolone is either alone or in addition to in-house treatment with the active substance. Opportunities for such use are:

  • allergic and / or inflammatory skin diseases
  • Eye diseases such as dermal inflammation or inflammation of the middle eye skin.
  • Diseases of the teeth, gums and oral mucosa such as acute gingivitis, inflammation of the mouth and inflammation of the gum pockets
  • Inflammatory hemorrhoids, inflammation in the anal area or rectal inflammation.

What is the purpose of this ingredient?

  • Inhibit inflammation
  • relieve allergic reactions
  • Balance functional weakness of the adrenal cortex
  • to compensate for the lack of hormone production in the pituitary gland
  • relieve rheumatic diseases
  • relieve diseased remodeling of connective tissue
  • relieve transient acute inflammation on multiple joints
  • positively influence chronic inflammation
  • treat heart disease
  • Alleviate bronchial and lung diseases such as bronchial asthma
  • Mitigate lung tissue disorders of various causes
  • Prevent respiratory distress syndrome in premature babies
  • Alleviate laryngeal and tracheal narrowing (such as pseudo-Krupp)
  • to cure allergic and or inflammatory skin diseases
  • Alleviate hay fever and allergic rhinitis
  • support cancer treatment
  • treat blood disorders of various causes
  • Alleviate symptoms of malignant disease
  • Prevent vomiting by chemo and treat
  • Alleviate infectious diseases
  • Alleviate Nerve Disorders
  • combat eye inflammation
  • Affect diseases of the digestive tract and liver
  • Alleviate kidney and urinary tract disease
  • relieve inflammatory gastrointestinal diseases

This is how Prednisolone works

Below you will learn more about the fields of application and the mode of action of Prednisolone.
Please also read the information on the drug groups glucocorticoids, anti-inflammatories, to which the drug prednisolone belongs.

Applications of the active ingredient prednisolone

Prednisolone is available in many different dosage forms. These include tablets, capsules, infusion solutions and injection solutions for internal (systemic) injection. For local (local) use, also in combination with other active ingredients, suppositories, ointments, creams, pastes, gel preparations, tinctures, drops and solutions are available.

Prednisolone is used in tablet form or given directly into the bloodstream at

  • Balancing treatment (substitution therapy) of adrenocortical insufficiency (Addison’s disease) and anterior pituitary weakness (first-line means hydrocortisone and cortisone)
  • Stress states after long-term cortisone therapy
  • Inflammatory rheumatic diseases such as inflammation of all joints (chronic polyarthritis) and acute inflammatory processes on individual joints for pain relief and anti-inflammatory
  • Inflammation of blood vessels
  • Disease with connective tissue remodeling (collagenosis) such as lupus erythematosus (butterfly lichen) to delay disease progression
  • Bronchial and pulmonary diseases such as bronchial asthma and COPD (concomitant administration of bronchodilators) and pulmonary tissue disorders of various causes
  • Diseases of the upper respiratory tract such as severe forms of hay fever and allergic rhinitis after the therapeutic failure of glucocorticoids to inhale and -spray
  • acute narrowing of larynx or trachea (in pseudo-Krupp also as a suppository) or for the prevention of respiratory distress syndrome in preterm infants
  • Heart disease such as pericarditis (endocarditis), including those caused by rheumatic inflammation
  • blood diseases of various causes
  • Diseases of the nervous system
  • Infections like meningitis due to tuberculosis
  • Diseases of the kidneys, ureters, bladder or urethra.
  • diseases of the digestive tract as well as inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease
  • liver diseases
  • the treatment of blood cancer (leukemia) and lymph node cancer. However, prednisolone only has a soothing effect on the symptoms; the cause of the disease is not treated as a result. In addition, the active ingredient also prevents the vomiting caused by chemotherapy.

Local administration of prednisolone is either alone or in addition to in-house treatment with the active substance. Opportunities for such use are:

  • allergic and / or inflammatory skin diseases
  • Eye diseases such as dermal inflammation or inflammation of the middle eye skin.
  • Diseases of the teeth, gums and oral mucosa such as acute gingivitis, inflammation of the mouth and inflammation of the gum pockets
  • Inflammatory hemorrhoids, inflammation in the anal area or rectal inflammation.

For the following application areas of Prednisolone , in-depth information is available:

  • Psoriasis
  • eczema
  • inflammation
  • allergy
  • asthma
  • COPD
  • acute bronchitis
  • inflammatory rheumatic diseases
  • liver inflammation
  • Multiple sclerosis
  • cirrhosis
  • chronic inflammatory bowel disease
  • Cancer (general)
  • chronic bronchitis
  • tuberculosis
  • Inflammation of the oropharynx
  • conjunctivitis
  • eczema
  • itching
  • hair loss
  • arthritis
  • skin infections
  • respiratory diseases with mucus
  • pneumonia
  • Eye infections caused by bacteria
  • Cardiovascular Disease
  • graft rejection

Mode of action of Prednisolone

Prednisolone belongs to the drug group of glucocorticoids. It contains no fluorine in its molecule and is quite similar to the body’s hydrocortisone. However, the active ingredient is one of the weaker effective agents of glucocorticoids. Depending on the dose, prednisolone affects the metabolism of almost all tissues.

In case of failure or weakness of the adrenocortical function, there is a lack of endogenous hydrocortisone. Hydrocortisone is needed to regulate carbohydrate, protein and fat metabolism. Prednisolone, taken as a tablet

Potential Prednisolone side effects may include:

Prednisolone used to treat the following diseases:

  1. Charles L. Scott says:
    5.0 rating

    Prednisolone for Surgery

    5 days application, (starting from maximum dose, later smaller dosage). No significant effects, but no side effects. Weight gain, depression … = Nul.

    Side effects: No side effects
  2. Sean B. Edwards says:
    4.0 rating

    Prednisolone for Psoriasis; Rheumatism

    After several months of discomfort due to psoriasis and muscle and body aches, I decided to take cortisone after an injection treatment in the shoulder joints. My rheumatologist also advised me to do so. The first week was = 2 x 5 mg prednisolone morning and evening 1 tablet a 5mg. In the second and third week, I took only 1 x 5mg in the morning. In the fourth week of the week, I took only 2.5 mg to cut. Already in the 2nd week I felt good, powerful, well rested, almost painless. The psoriasis went back, itching and shivering no more. My bleeding gums disappeared. Now, after discontinuing the drug, the pain comes back, the psoriasis flakes again and the general bruise returns. I had no side effects but only good effects.

    Side effects: No side effects
  3. Mai R. McMillen says:
    3.5 rating

    Prednisolone for Psoriasis

    because of an aggressive psoriasis the second time Predni. Hair loss, hot flashes, chest pressure, racing heart. Question, does the hair grow back when I release cortisone?

  4. Patricia W. Hedrick says:
    3.0 rating

    Prednisolone for Angioedema

    Take 2x 20 mg per day. From the second day I got hot flashes towards evening, felt like fever. Hot carriages, hands, feet. Tingling in the feet. What I did not notice is that the partially blurred vision, even from the tablets. The Quincke edema was gone after a day, but the cheek under it was still thick.

    Side effects: Hot flashes
  5. Cynthia J. Rowlett says:
    3.5 rating

    Prednisolone for Angioedema; Skin rash

    No visible side effects, except at higher dose (from 1x 50mg per day) severe fatigue and laxity. I take Prednisolone only if necessary and decide if I take 10 mg, 25 mg or 50 mg, depending on the severity and location of the swelling. Previously, I try to mitigate with Fenistiltropfen that also make me very tired. Weight gain within 2 years 15 kg. Probably not only the medication, but also possibly menopause and the diet not adapted to it, less exercise than before my illness, constant stress on work.

    Side effects: Fatigue
  6. Jessica R. Howard says:
    3.0 rating

    Prednisolone for Sweat; Blurred vision; Pain (back)

    Prednisolone did not help me at all. The strong back and abdominal pain did not make it easy for me to take it. In addition, there were depressions that lasted for a long time and greatly affected my work …

  7. Dara R. Punch says:
    5.0 rating

    Prednisolone for Blurred vision

    I was 10 days outpatient in the university in 2008 and it was an inflammatory process on the hypothalamus found (which was up to the Sehnerv effect and I thereby had double images). neurosarcoidosis was diagnosed. but no serious. I got urbasol by infusion for 3 days and then it went away. so far, I’ve had little problems since then. no headache or anything. everything is well cured / declined. At the moment I see (due to work-related stress / overexertion – christmas business) again a little \\\ over cross \\\ left eye looks so far clear, but looks slightly to the right, right looks slightly blurry. I notice that the nerve is currently overwrought. something is not right. I feel it. I often feel dizzy and the picture wobbles. I have to support myself from time to time when walking or moving. I already ran against objects and got blue spots. tonight I have 4 pcs. Prednisolone 10mg taken, as the dizzy annoyed me. hats then worked after 1.5 hours. class 🙂 finally the madness gone. Tomorrow I will take another 4 and the day after tomorrow 3. then the inflammation will – hopefully – have subsided.

    Side effects: No side effects
  8. Derrick K. Lewis says:
    3.0 rating

    Prednisolone for Heartburn; Morbus crohn

    Persistent use of Prednisolone sponges the body and the skin becomes thin and cracked. So-called pregnancy scars have remained with me. Often you also get strong acne.

    Side effects: Acne; Water storages
  9. Marjorie J. Romero says:
    4.0 rating

    Prednisolone for Uveitis

    Mainly positive side effects that I never expected. Get smooth skin and pimple away, never had pimple-free skin. Cystitis and coughing away, which I had for months. Somehow, everything was somehow connected. Then my depris went away, was finally back to normal. Gum bleeding away, hair loss away and no more problems with gluten. Little sleep and a little tachycardia, slight knee pain in the evening and weight loss despite a lot of food were everything. but I can accept it because of the positive effects, would prefer to take longer, but should not be good in the long run. I do not know what’s going on in my body, but apparently I need the cortisone. Quite strange that I have the opposite of side effects. The only problem is that I already weigh little and despite the cravings and the constant eating further lose weight. Everything seems to go through me.

  10. William I. Burns says:
    3.5 rating

    Prednisolone for Uveitis

    I have had a severe inflammation on my eye for a few weeks now. After drops, ointments and cortisone-containing eye drops did not help, I got the tablets prescribed. 60 mg a day. I do not feel hungry. I’m pretty relaxed I do not care. I’m not tired, I have sleep problems. Diarrhea started on the 4th day. So far, the inflammation has not improved.

    Side effects: Anorexia; Diarrhea; Insomnia
  11. Priscilla R. Reimann says:
    4.5 rating

    Prednisolone for Bell's palsy

    Treatment with prednisolone (1st infusion, then daily 100mg for 5 days) had hardly any effect on the paralysis of the face, which is not uncommon in this disease. In fact, I suffer more from the side effects of the drug than from the disease itself. I felt very tired or very hyperactive since the second day of taking it, which could change every hour. I’m hardly able to drive or follow a more complex conversation. My otherwise over-punctual cycle has been postponed by 4 days, and that after 3 days of taking … In addition, I have increased 3 kg. Cortisone may be a great drug, but I’ll get an alternative treatment. Do not want to know what a long-term therapy must be like this!

    Side effects: Fatigue; Increase in weight
  12. Page J. Keen says:
    4.5 rating

    Prednisolone for Bell's palsy

    Because of peripheral facial palsy I need to take Prednisolone, 100 mg for the first 7 days, then dose down for 9 days. The paresis has not improved so far, but in the course of treatment, more side effects of cortisone occur. At the beginning it was just an evening headache, today on day 7 I had some incredibly weak legs and constantly on the toilet. From tomorrow will be dosed down luckily.

  13. Janie R. Kim says:
    4.0 rating

    Prednisolone for Fibromyalgia; Rheumatism

    the pain in the left arm, (shoulder and muscle area) is suppressed. After short-term discontinuation of the drug again came on violent pain. After about 4 weeks of taking the drug it started in my joints with heavy cracking, it affects all my joints. That’s not so bad, but lately I realize that the drug has no positive effect on my bones or articular cartilage. Have suddenly a terrible effect on my cervix and other joints (pain and stiffness of the affected joints) I will slowly stop the drug. Just hope that the side effects, after taking this drug, someday be balanced by the body.

  14. Kathryn S. Jones says:
    2.5 rating

    Prednisolone for Collagen defect

    Due to the drug, unfortunately, I got the well-known full moon face in a short time, and gained a lot of weight. Whether it is extra weight or water retention, I can not say exactly, but I feel very uncomfortable in the form. In addition, I often had severe headaches at the beginning of treatment. Otherwise, the drug acts like doping, you are wide awake and can not sleep well. If the illness were not so painful, I would immediately give up the drug.

  15. Hazel B. Tillman says:
    3.5 rating

    Prednisolone for Neurodermatitis

    The drug worked already after about 1 hour. It was administered because of severe itching and burning of the skin, as within 30 min. Had developed a purple eczema on the hands. The eczema became lighter from the next day and disappeared after 2 weeks. However, I had to vomit several times between the second and fifth days of use, which led to a rapid weight loss in an underweight already existing. Approximately 1 week after taking up to 3 months there was an increased hair loss.

    Side effects: Vomit; Hair loss
  16. Vilma L. Broyles says:
    2.0 rating

    Prednisolone for Psoriatic arthritis

    Strong urinary urgency. Good and fast effect on skin and musculoskeletal system.

    Side effects: Urinary frequency