Prednisolone

3.5 rating based on 231 ratings
Rating: 3.5 Reviews: 231
Prednisolone

Prednisolone is available in many different dosage forms. These include tablets, capsules, infusion solutions and injection solutions for internal (systemic) injection. For local (local) use, also in combination with other active ingredients, suppositories, ointments, creams, pastes, gel preparations, tinctures, drops and solutions are available.

Prednisolone is used in tablet form or given directly into the bloodstream at

  • Balancing treatment (substitution therapy) of adrenocortical insufficiency (Addison’s disease) and anterior pituitary weakness (first-line means hydrocortisone and cortisone)
  • Stress states after long-term cortisone therapy
  • Inflammatory rheumatic diseases such as inflammation of all joints (chronic polyarthritis) and acute inflammatory processes on individual joints for pain relief and anti-inflammatory
  • Inflammation of blood vessels
  • Disease with connective tissue remodeling (collagenosis) such as lupus erythematosus (butterfly lichen) to delay disease progression
  • Bronchial and pulmonary diseases such as bronchial asthma and COPD (concomitant administration of bronchodilators) and pulmonary tissue disorders of various causes
  • Diseases of the upper respiratory tract such as severe forms of hay fever and allergic rhinitis after the therapeutic failure of glucocorticoids to inhale and -spray
  • acute narrowing of larynx or trachea (in pseudo-Krupp also as a suppository) or for the prevention of respiratory distress syndrome in preterm infants
  • Heart disease such as pericarditis (endocarditis), including those caused by rheumatic inflammation
  • blood diseases of various causes
  • Diseases of the nervous system
  • Infections like meningitis due to tuberculosis
  • Diseases of the kidneys, ureters, bladder or urethra.
  • diseases of the digestive tract as well as inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease
  • liver diseases
  • the treatment of blood cancer (leukemia) and lymph node cancer. However, prednisolone only has a soothing effect on the symptoms; the cause of the disease is not treated as a result. In addition, the active ingredient also prevents the vomiting caused by chemotherapy.

Local administration of prednisolone is either alone or in addition to in-house treatment with the active substance. Opportunities for such use are:

  • allergic and / or inflammatory skin diseases
  • Eye diseases such as dermal inflammation or inflammation of the middle eye skin.
  • Diseases of the teeth, gums and oral mucosa such as acute gingivitis, inflammation of the mouth and inflammation of the gum pockets
  • Inflammatory hemorrhoids, inflammation in the anal area or rectal inflammation.

What is the purpose of this ingredient?

  • Inhibit inflammation
  • relieve allergic reactions
  • Balance functional weakness of the adrenal cortex
  • to compensate for the lack of hormone production in the pituitary gland
  • relieve rheumatic diseases
  • relieve diseased remodeling of connective tissue
  • relieve transient acute inflammation on multiple joints
  • positively influence chronic inflammation
  • treat heart disease
  • Alleviate bronchial and lung diseases such as bronchial asthma
  • Mitigate lung tissue disorders of various causes
  • Prevent respiratory distress syndrome in premature babies
  • Alleviate laryngeal and tracheal narrowing (such as pseudo-Krupp)
  • to cure allergic and or inflammatory skin diseases
  • Alleviate hay fever and allergic rhinitis
  • support cancer treatment
  • treat blood disorders of various causes
  • Alleviate symptoms of malignant disease
  • Prevent vomiting by chemo and treat
  • Alleviate infectious diseases
  • Alleviate Nerve Disorders
  • combat eye inflammation
  • Affect diseases of the digestive tract and liver
  • Alleviate kidney and urinary tract disease
  • relieve inflammatory gastrointestinal diseases

This is how Prednisolone works

Below you will learn more about the fields of application and the mode of action of Prednisolone.
Please also read the information on the drug groups glucocorticoids, anti-inflammatories, to which the drug prednisolone belongs.

Applications of the active ingredient prednisolone

Prednisolone is available in many different dosage forms. These include tablets, capsules, infusion solutions and injection solutions for internal (systemic) injection. For local (local) use, also in combination with other active ingredients, suppositories, ointments, creams, pastes, gel preparations, tinctures, drops and solutions are available.

Prednisolone is used in tablet form or given directly into the bloodstream at

  • Balancing treatment (substitution therapy) of adrenocortical insufficiency (Addison’s disease) and anterior pituitary weakness (first-line means hydrocortisone and cortisone)
  • Stress states after long-term cortisone therapy
  • Inflammatory rheumatic diseases such as inflammation of all joints (chronic polyarthritis) and acute inflammatory processes on individual joints for pain relief and anti-inflammatory
  • Inflammation of blood vessels
  • Disease with connective tissue remodeling (collagenosis) such as lupus erythematosus (butterfly lichen) to delay disease progression
  • Bronchial and pulmonary diseases such as bronchial asthma and COPD (concomitant administration of bronchodilators) and pulmonary tissue disorders of various causes
  • Diseases of the upper respiratory tract such as severe forms of hay fever and allergic rhinitis after the therapeutic failure of glucocorticoids to inhale and -spray
  • acute narrowing of larynx or trachea (in pseudo-Krupp also as a suppository) or for the prevention of respiratory distress syndrome in preterm infants
  • Heart disease such as pericarditis (endocarditis), including those caused by rheumatic inflammation
  • blood diseases of various causes
  • Diseases of the nervous system
  • Infections like meningitis due to tuberculosis
  • Diseases of the kidneys, ureters, bladder or urethra.
  • diseases of the digestive tract as well as inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease
  • liver diseases
  • the treatment of blood cancer (leukemia) and lymph node cancer. However, prednisolone only has a soothing effect on the symptoms; the cause of the disease is not treated as a result. In addition, the active ingredient also prevents the vomiting caused by chemotherapy.

Local administration of prednisolone is either alone or in addition to in-house treatment with the active substance. Opportunities for such use are:

  • allergic and / or inflammatory skin diseases
  • Eye diseases such as dermal inflammation or inflammation of the middle eye skin.
  • Diseases of the teeth, gums and oral mucosa such as acute gingivitis, inflammation of the mouth and inflammation of the gum pockets
  • Inflammatory hemorrhoids, inflammation in the anal area or rectal inflammation.

For the following application areas of Prednisolone , in-depth information is available:

  • Psoriasis
  • eczema
  • inflammation
  • allergy
  • asthma
  • COPD
  • acute bronchitis
  • inflammatory rheumatic diseases
  • liver inflammation
  • Multiple sclerosis
  • cirrhosis
  • chronic inflammatory bowel disease
  • Cancer (general)
  • chronic bronchitis
  • tuberculosis
  • Inflammation of the oropharynx
  • conjunctivitis
  • eczema
  • itching
  • hair loss
  • arthritis
  • skin infections
  • respiratory diseases with mucus
  • pneumonia
  • Eye infections caused by bacteria
  • Cardiovascular Disease
  • graft rejection

Mode of action of Prednisolone

Prednisolone belongs to the drug group of glucocorticoids. It contains no fluorine in its molecule and is quite similar to the body’s hydrocortisone. However, the active ingredient is one of the weaker effective agents of glucocorticoids. Depending on the dose, prednisolone affects the metabolism of almost all tissues.

In case of failure or weakness of the adrenocortical function, there is a lack of endogenous hydrocortisone. Hydrocortisone is needed to regulate carbohydrate, protein and fat metabolism. Prednisolone, taken as a tablet

Potential Prednisolone side effects may include:

Prednisolone used to treat the following diseases:

  1. Connie K. Fritsche says:
    4.0 rating

    Prednisolone for Bubble searches

    Duch the high prednisolone dose to 100 mg strong Gewichstzunahme about 17 kg. Have then wg. a boost but again decreased 15 kg – could eat anything for about 6 months (Fresubin). I received insidone (anti-depressants) and then 10 kg over time – prednisolone was continued to take about 15 mg and azatioprin 25 mg a day.

    Side effects: Increase in weight
  2. Christopher L. Owens says:
    4.0 rating

    Prednisolone for Asthma

    Significant weight gain, bones become brittle (already had 2 arm breaks always in the same place), tendons become brittle (in 2003, two times Achilles tendon rupture in the left leg and 2007 Achilles tendon rupture in the right leg), knee surgery in January 2007 because of bad Knorbelgewebe. I have the impression that the drug is eating me up slowly.