Following is information on contraindications to the use of amlodipine in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should amlodipine not be used?
The active substance must not be used with
- Hypersensitivity to amlopidine or related calcium channel blockers (dihydropyridines)
- Cardiovascular shock, acute myocardial infarction within the first four weeks
- A more severe constriction of the main artery (aortic stenosis) or a Herzge at rest (rest angina, unstable angina pectoris)
- concurrent treatment with beta-blockers injected intravenously (into the veins).
The use of amlodipine should be administered only after careful risk-benefit assessment by the physician.
- Patients with severe hepatic impairment
- Severe kidney disease and dialysis patients, as the hypotensive effect of amlodipine may be increased
- Patients with cardiac insufficiency (congestive heart failure) or who already have significantly reduced blood pressure with a systolic value below 90 mmHg. This requires particularly careful medical supervision.
What should you watch out for during pregnancy and lactation?
In pregnancy and lactation, amlopidine should not be used.
If the active ingredient is taken until shortly before the expected date of birth, an extension of the birth process and a disturbance of the labor activity can not be excluded.
Amlopidin may pass into breast milk. Therefore, should be weaned, if during breast-feeding a treatment with amlopidine is necessary.
What should be considered in children?
The substance should not be used in children and adolescents under the age of 18 because the effects of amlopidine are not well understood in this patient population.
Warnings and Precautions
- Reduced blood pressure may be associated with impaired liver function.
- Dropping blood pressure by taking the drug can affect your ability to react so much that driving a car and operating machinery are dangerous.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.