About Nexium

3.0 rating based on 55 ratings
Rating: 3.2 Reviews: 55
About Nexium

Esomeprazole is mostly taken; where ingestion is not possible, the active ingredient can also be given as an injection.

What is the purpose of this ingredient?

  • Reduce gastric acid production
  • Accelerate ulcerations in the stomach and duodenum
  • Alleviate pain in esophageal inflammation and gastric ulcer and duodenal ulcer
  • Prevent inflammation of the esophagus and ulcers in the stomach and duodenum
  • treat and prevent acid-related diseases.

This is how Esomeprazol works

Below you will learn more about the fields of application and the mode of action of esomeprazole.
Please also read the information on the drug groups proton pump inhibitor, means against excessive stomach acid, to which the active ingredient esomeprazole belongs.

Areas of application of the active substance esomeprazole

Esomeprazole is mostly taken; where ingestion is not possible, the active ingredient can also be given as an injection.

Esomeprazole is used to reduce stomach acid. It is used for the therapy and prevention of heartburn and inflammation of the esophagus as well as for Helicobacter pylori-related gastric and duodenal ulcers.

In acute esophagitis, 40 milligrams of esomeprazole are recommended once daily for four weeks or more. For prevention, a dose of 20 milligrams of esomeprazole a day is sufficient. As part of a one-week eradication therapy, 20 milligrams of esomeprazole are taken twice a day in combination with two antibiotics.

Ulcerative diseases that are due to a long-term medication (for example, non-steroidal anti-inflammatory drugs) are treated with a daily dose of 20 milligrams of esomeprazole. If patients are permanently dependent on these medicines, they can also be treated with esomeprazole as a preventive measure.

Another application of the drug is the so-called Zollinger-Ellison syndrome. It is a form of cancer whose cells produce the hormone gastrin. Gastrin stimulates the release of gastric acid. The increased gastric acid attacks the mucous membrane of the stomach and duodenum as well as the esophagus and leads there to ulcers. Esomeprazole is used in addition to the drugs for the treatment of tumors against the consequences of excess gastrin production.

For the following application areas of Esomeprazol , in-depth information is available:

  • Gastric and duodenal ulcers
  • Heartburn and esophagitis

Mode of action of esomeprazole

Esomeprazole belongs to the group of proton pump inhibitors. Like all drugs in this group, esomeprazole also reduces the release of stomach acid. This can help prevent and treat heartburn and inflammation of the esophagus and speed up the healing of gastric and duodenal ulcers.

Esomeprazole is a modified form of omeprazole, which is also a proton pump inhibitor. Proton pump inhibitors prevent the formation of gastric acid (hydrochloric acid). While omeprazole exists in two different physical forms with different potencies, esomeprazole is the isolated pure physical form. Therefore esomeprazole is better absorbed by the body and has a stronger effect.

Esomeprazole is a drug precursor (prodrug) and is only in the body in the actually effective form converted. After it has reached the parietal cells of the stomach via the bloodstream, the active active form is created in the acidic environment of the cells. It couples inextricably to the so-called proton pump in the wall of the parietal cell and blocks it. As a result, less stomach acid is released.

Esomeprazole is administered in enteric-coated drug forms (for example, prolonged-release tablets). This prevents premature drug decomposition in the acidic environment of the stomach. Only after reaching the small intestine esomeprazole is released and can be taken from here into the bloodstream. Also an injection directly into the bloodstream is possible.

The effect begins one hour after taking Esomeprazole and lasts for 12 to 24 hours.

Potential Nexium side effects may include:

Nexium used to treat the following diseases:

  1. Michael P. Obrien says:
    4.5 rating

    Nexium for Reflux

    Enlargement of the breast, formation of canals, chest pain after several years of Nexium.

  2. Daniel C. Berman says:
    4.5 rating

    Nexium for Reflux

    I only got a red head after taking it over a longer period of time (about 18 months.) The skin in the facial area glows, I then tried other remedies like Ranitic 300 and Pantozol 40, which led to the same effect Months I take Pariet 20 with success and I do not get a red head anymore.

  3. Cornelia R. Rouse says:
    3.0 rating

    Nexium for Stomach protection; Stomach complaints; Reflux

    Due to the reflux stomach and the many medications I have to take, I depend on Nexium and Talcid. So far, I tolerate both drugs quite well and feel no side effects can recommend both.

    Side effects: No side effects
  4. Karen D. Martinez says:
    4.5 rating

    Nexium for Hurt

    I had been struggling with recurring abdominal pain and throats for years. My new doctor has asked a bit more closely and then said that he would like to try something because he has a suspicion that it may have to do with stomach acid. He prescribed Nexium for me and I have been taking this medication for 14 days. After 3 days of application, the pain had completely disappeared. Also disappeared were blows and falls, as well as permanent urinary tract infections with which I also had to fight for years daily. I was always tired … that too is gone. I feel very well and am angry that so far no doctor has come up with the idea that it was a sour problem. Instead, they sent me to stomach and colonoscopy … more than once: What fun. Had I known about the drug before, I would have spared a lot of running, pain, and unpleasant procedures (and a lot of money for over-the-counter medicines).

    Side effects: No side effects
  5. Dustin A. Felix says:
    2.5 rating

    Nexium for Stomach complaints

    more intense gas formation, no fatigue a little less solid stool

    Side effects: Flatulence
  6. Stacy J. Wasser says:
    4.0 rating

    Nexium for Hurt; Stomach complaints

    Take for about 2.5 years Seroquel. Have begun with a stay in the clinic, after Jarsin has brought nothing. I started slowly and then got into the clinic on a daily dose of 300mg. About half a year later I took 10 mg of fluoxetine in consultation with my therapist. It went well for a while, but eventually it was not enough anymore. Then had to go to 400 mg of seroquel and 10 mg of fluoxetine. So in the morning and in the evening 200 mg of seroquel and 10 mg of fluoxetine in the morning. At some point Ferro Sanol was added due to iron deficiency. A short time later I had to go again 50 mg with the Seroquel higher, 450 mg daily. At the beginning of this year, 20 mg Nexium mmorgens were added due to gastrointestinal problems. Had to undergo a gastrointestinal spotting at the hospital. It turns out that I have a stomach, an intestinal inflammation and chronic heartburn. So I have to take Nexium for the stomach now. In the middle of this year, the sero dose was again increased by 50 mg. Now take 500 mg Seroquel, 10 mg Fluoxetine, 20 mg Nexium, 40 mg Ferro Sanol and Yasmin. Sin a lot of pills every day, but without it does not work. When I started with the Seroquel, I was pretty flat for the first 2 weeks. I was tired all day and just wanted to sleep. Preferably the whole day, but that was not possible in the clinic because of the therapies. After about 3 weeks the fatigue would be less and less. After that, my daily routine was okay again. When the Seroquel was raised to 500mg this year, fatigue returned. I slept up to 17 hours a day. It’s getting a lot harder for me to get up. It took me a long time to catch myself first. After sleeping, I did not get much on the line. I was broken as if. In addition, there was also dizziness. When after 3 weeks the fatigue and the daily dizziness were less, I was also to use something again. Meanwhile, I get along so well with all the medication. In the 2.5 years, I myself several times tried to sell the drug. I would not recommend this to anyone without medical attention, as I did. I was totally crazy and had a lot of mood swings, which turned from one to the other minute. I could not sleep anymore. Was then awake up to 3 days at a time. When I said that it would not work, I took the medication again. Until the mirror has first rebuilt went 2-3 days in the country. After that I could sleep again. I would not advise anyone to do it the way I gamacht. The times without the medication were the horror. Since I have my experiences with it, I do not even try to sell it alone. I take my medication as it is agreed with my therapist and that’s good too. However, I need at least 8 hours sleep. This is nothing. 8 hours are the limit. Sleep an average of 9-9.5 hours per night. But also clearly notice that I need it.

    Side effects: Dizziness; Fatigue
  7. David C. Turner says:
    4.0 rating

    Nexium for High blood pressure; Heartburn; Reflux

    SUBSTANTIAL TASTE CHANGE TO BITTER. In particular, the morning coffee – although very dilute – sometimes tasted disgusting. Also bread, rolls and cakes were bitter in the taste. Have each set off a drug for days to find out which pill is the cause. My first suspicion is NEXIUM mups, then maybe ASS.

    Side effects: Taste alteration
  8. Earl H. Rouse says:
    3.0 rating

    Nexium for Heartburn; Reflux

    I took 1 tbl of Nexium every 2 days for heartburn. Since the morning after the second tablet everything tastes only BITTER! A few months ago, I had that once, then I pushed it on the heartburn, now I read the leaflet and promptly found the taste disorders. Interestingly, this is also in Antra (Omep etc.), the first drug of this group of drugs in the package insert, but not in Pantozol a development. Maybe I’ll try this one.

    Side effects: Taste alteration
  9. Rena R. Prado says:
    3.0 rating

    Nexium for Gastritis

    I have recently irritable bowel tachycardia cardiac arrhythmia fatigue and much more, I’ve read that in the forum I’m sure of skin problems since a year I never had. ..

  10. Peter V. Ruhl says:
    3.5 rating

    Nexium for Reflux

    Has long-term effect on the endodrine system, with consequences of reduced libido, drive weakness, distended stomach. Whether prolonged side effects remain, can not yet be assessed. Side effects are also effects, but unwanted!

    Side effects: Libido loss; Stomach pain
  11. Charles J. Gaines says:
    2.0 rating

    Nexium for Hiatal hernia

    Flatulence, dry mouth, reactions to alcohol I take Nexium Mups 40mg now for 3 years every second day before going to bed. I always have a dry mouth after taking it and the next day flatulence (which I reasonably get in the way of Lafax.) Furthermore, when I am drinking alcohol the following day, I have a strong reddening and swollen eyes.

    Side effects: Mouth dryness; Flatulence
  12. Holley F. Layman says:
    4.0 rating

    Nexium for Esophagus inflammation

    At first, I took 20 mg. Unfortunately, it was already 40 mg after 3 years and now I am already at 80 mg daily. The body gets used to it and over time needs more and more in order to achieve the effect. Nevertheless, I have heartburn on a daily basis, chronic strep throat, etc. But with every dose increase, significant NW were added. Constipation, weight gain, headache, depris, hair loss, muscle and joint pain. Tiredness, listlessness, etc.

  13. Dale H. Knight says:
    3.0 rating

    Nexium for Hurt

    My friend got hives after 2 days. It has been a year since and without anti-allergic nothing works. please keep your fingers away from this drug!

    Side effects: Allergic skin reaction