Following is information on contraindications to the use of gabapentin in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should gabapentin not be used?
Gabapentin must not be used with:
- Hypersensitivity to the active substance
- acute pancreatitis. If symptoms develop during treatment that may indicate an onset of pancreatitis (such as upper abdominal discomfort, nausea, vomiting), the doctor will usually need to stop taking gabapentin.
Gabapentin should only be used under strict medical supervision at:
- decreased kidney function
- chronic pancreatitis
- Psychoses in the Prehistory of the Patient
- mixed (general and focal) epileptic seizures, including absence.
What should you watch out for during pregnancy and lactation?
Gabapentin should be administered during pregnancy and lactation only after careful benefit-risk consideration by the doctor. In animal experiments gabapentin caused damage to the unborn child.
Gabapentin passes into breast milk. So far, however, no harm has been known to infants. Nevertheless, it should be weaned for safety.
What should be considered in children?
Children under the age of three are not allowed to receive gabapentin. At the age of three to twelve years, gabapentin should be used in children only as adjunct therapy in combination with other antiepileptic drugs. However, the manufacturers make different statements on this point, so first read the leaflet and consult the doctor.
Children over the age of twelve may also be treated alone with gabapentin (as a single therapy).
The treatment of nerve pain with gabapentin is not allowed in children.
Warnings and Precautions
- In combination with other antiepileptic drugs, the effect of hormonal contraceptives (“pill”) may be compromised. Additional mechanical methods of contraception (condoms) are required.
- In case of upper abdominal discomfort, nausea and vomiting there is a suspicion of pancreatitis and the doctor should be consulted immediately.
- Dose reductions, discontinuation or replacement
Other antiepileptic drugs should be taken gradually for at least a week.
- Apparently taking the drug increases suicidal tendencies, so patients should be monitored carefully by the doctor and family members.
- Reactivity may be so impaired by the active substance that active participation in road traffic and the use of machinery are dangerous.
- Certain urine tests (for example, on urine protein) may be false-positive by taking the drug.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.