About Neurontin

3.5 rating based on 16 ratings
Rating: 3.5 Reviews: 16
About Neurontin

Gabapentin is used in adults and children over the age of twelve, who suffer from epilepsy that affects only part of the brain, that is, has a so-called focal origin (also called focal seizures). Seizures that spread from one point in the brain (“focus”) to the entire brain later (so-called secondary generalized seizures) can also be treated with gabapentin. For this purpose gabapentin can also be combined with other antiepileptic drugs. These combinations are already suitable for use in children over the age of three years.

What is the purpose of this ingredient?

  • Reduce overexcitability of nerve cells
  • Increase seizure threshold
  • treat certain nerve pain like diabetic neuropathy
  • treat epilepsy
  • Prevent epileptic seizures
  • Improve tremors without organic cause (essential tremor)

This is how Gabapentin works

Below you will learn more about the fields of application and the mode of action of gabapentin.
Please also read the information on the drug group antiepileptic drugs,
to which the active ingredient gabapentin belongs.

Areas of application of the active substance gabapentin

Gabapentin is used in adults and children over the age of twelve, who suffer from epilepsy that affects only part of the brain, that is, has a so-called focal origin (also called focal seizures). Seizures that spread from one point in the brain (“focus”) to the entire brain later (so-called secondary generalized seizures) can also be treated with gabapentin. For this purpose gabapentin can also be combined with other antiepileptic drugs. These combinations are already suitable for use in children over the age of three years.

Gabapentin is also effective against certain adult neuralgia such as diabetic neuropathy, postherpetic neuropathy and others.

Some other diseases are also occasionally treated with gabapentin. However, these indications are not covered by clinical studies and the active substance is not approved. These include certain pains (for example, facial muscle pain), degeneration and damage to nerves (amyotrophic lateral sclerosis), complications of multiple sclerosis (trigeminal neuralgia, painful cramps, etc.), balance disorders with tremor, tremor, trembling without organic cause (essential tremor), or Status epilepticus, which does not respond to other antiepileptic drugs.

For the following application areas of Gabapentin , in-depth information is available:

  • epilepsies
  • Pain (mild to moderate)

How gabapentin works

The mechanism of action of gabapentin is not yet well known. Its chemical structure is similar to gamma-amino butyric acid (GABA), an important inhibitory messenger between neurons. Nevertheless, it does not bind to the corresponding binding sites in the brain like the body’s own GABA and prevents the transmission of stimuli there. Rather, the effect seems to come about indirectly because more of the body’s own GABA is being produced. This then exerts the stimulus inhibition. It is further suspected that an influence on the metabolism of other endogenous neurotransmitters, but evidence is still pending.

Gabapentin is not effective in atrial (primary) generalized seizures, such as absences. It can even worsen this type of seizure. Its advantage is the good compatibility compared to other antiepileptic drugs. Also, gabapentin has little adverse effects on concentration, wakefulness and responsiveness.

Potential Neurontin side effects may include:

Neurontin used to treat the following diseases:

Disease
Percentage
14%
14%
  1. Michelle E. Bittner says:
    3.0 rating

    Neurontin for Epilepsy

    The drug worked quite well, but eventually I got a lot of muscle problems and could not move properly. So that was also phased out and Lamotrigin started. Greeting Anke

  2. Diane J. Clark says:
    4.0 rating

    Neurontin for Rls

    Sifrol has no serious side effects. Other dopamine agonists, such as cabaseril, which has a much better effect, can cause heart or lung fibrosis. Otherwise, the drugs are without side effects.

    Side effects: No side effects
  3. Samantha O. Doyle says:
    4.5 rating

    The more I slipped, the more stupid I became and the more weight I gained until I finally had enough and we stopped trying. Stunned head, brain packed in cotton, 8 kg heavier and the pain was still there …

    Side effects: Increase in weight; Dizziness
  4. Mitchell E. Cooley says:
    4.0 rating

    Neurontin for Epilepsy

    Weight gain and pronounced erectile dysfunction, after discontinuation early recovery

    Side effects: Increase in weight
  5. Sherman K. Knox says:
    2.5 rating

    Neurontin for Trigeminal neuralgia

    I take the drug Neurontin already 9 weeks to start only 1 tablet in the evening for 5 days in the morning and in the evening. At the beginning with the first tablet, I was very dizzy, headache, but now it is better. Otherwise I contract the tablets well.

    Side effects: Headache; Dizziness
  6. Malisa R. Closson says:
    4.0 rating

    Constipation, insomnia, fluid retention, skin rash, arrhythmia

    Side effects: Constipation
  7. Juan R. Ruiz says:
    4.5 rating

    Dizziness, headache, rising heat, facial flushing, increased blood pressure

    Side effects: Headache; Dizziness
  8. Laurie P. Garcia says:
    4.0 rating

    Hi everyone, I took Lyrica for 4 weeks (2 x 75 mg). I got her from the pain clinic because I was there because of my pain. Previously, tramadol, novamine sulfone, ibuprofen, musaril, amytriptiline etc. were announced. No effect on my pain. Only through Lyrica I became pain free. However, I did not tolerate it well. But that is different with every person. I had the following side effects: bloated stomach, severe constipation, dizziness (but less over time), redness. That’s why I switched to Neurotin 100 mg. The dose was 300 mg in the morning, 200 mg at noon and 300 mg in the evening. Impeccably painless only when slimming Lyrica and creeping in Neurotin the pain came through. But that’s usually the case. Unfortunately, I also had to stop taking Neurotine, even though overall it was still a low dose (according to the Pain Clinic). I had a moderate constipation – I could handle it, because it was much better than Lyrica. But after a good 2 weeks, cardiac arrhythmias and insomnia were added. Too bad – because even with this drug, I was painless. Now I have been taking Carbamazepine 200 mg for only a few days (once in the evening). I can not say much about side effects yet. I’m also painless with this drug and hopefully I’m lucky that the side effects are limited this time.

    Side effects: Constipation; Dizziness
  9. Carrie D. Smith says:
    2.0 rating

    Neurontin was my last rescue after trying everything! I have no side effects !! Have a HEALTHY 3 1/2 year old daughter, with Neurontin in pregnancy and 8 months breastfeeding !! Thank you, that Neurontin exists !! The Yasmin I also contracted without problems.

    Side effects: No side effects
  10. Teresa B. Patterson says:
    3.0 rating

    Neurontin for Rls

    I have a very serious idiopathic restless leg syndrome. At first I was not treated at all, then I was hospitalized with wrong or even antagonistic medication until I myself, because I knew what I was suffering, visited a restless legs ambulance far away from my place of residence and was treated there successfully. Since my illness is so bad, I got a combination therapy with the ergolinen dopamine agonist Cabaseril, which I had to discontinue after three years, because of the occurrence of cardiac fibrosis. Afterwards a non-ergoline dopamine agonist was searched for, from Requip to Sifrol and finally to Neupro 8mg 2Pflaster a day. I feel no effect. The patch has no side effects. When I take Dolzam (= Tramal) together with Rivotril I am slowly sneaking away and Neurontin 400mg is doing much better. Cabaseril was better than Neupro, but it had life-threatening side effects, so I can not take it anymore.

    Side effects: No side effects
  11. Hildegard W. Ruiz says:
    4.0 rating

    Neurontin for Rls

    I suffer from a very serious RLS. The dose of Neupro is very high and is 16mg / day. Since I have been suffering from RLS for 20 years, the symptoms have changed. Now I suffer the most in the morning under RLS. I feel better after taking my drops. I think I have to reduce the dose of Neupro. At Neupro, however, I am free of stomach problems or other side effects. For other dopamine agonists, I had to change the treatment because of side effects like cardiac fibrosis or hypotonic bladder.

    Side effects: No side effects
  12. Melissa R. Freese says:
    3.0 rating

    Memory disorders, fatigue

    Side effects: Fatigue