The following provides information on contraindications to the use of naproxen in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should Naproxen not be used?
In case of hypersensitivity to naproxen or to other non-steroidal anti-inflammatory drugs such as acetylsalicylic acid, the active substance should not be taken.
Patients who have an increased tendency to bleed should not take naproxen because it affects blood clotting. This affects, for example, patients who have suffered a stroke or a heart attack and now take blood-thinning drugs. Patients with blood clotting or coagulation disorders should not use naproxen without medical advice.
Naproxen itself can cause gastric and intestinal ulcers. Patients with a history of gastrointestinal ulcer or gastrointestinal discomfort, inflammatory bowel disease such as Crohn’s disease or ulcerative colitis should take the drug only after careful risk-benefit assessment by the doctor.
Patients with bronchial asthma, hay fever (allergy), nasal polyps or chronic respiratory tract infections should only use naproxen under regular medical supervision.
Patients with severe heart failure should not take naproxen. In cases of mild heart failure, acute metabolic disorders such as hepatic porphyria, hepatic dysfunction or hypertension, patients should consult their physician before use. This also applies to the elderly, children, alcoholics and patients with certain immune disorders such as systemic lupus erythematosus or mixed connective tissue disease.
Patients with renal impairment (renal insufficiency) may experience a deterioration in renal function due to naproxen. A special medical observation is required here.
Naproxen should only be taken with special medical care immediately after major surgery.
What should you watch out for during pregnancy and lactation?
During the first six months of pregnancy, naproxen must be taken only after careful medical benefit-risk assessment. In the last three months the active substance must not be used.
During breast-feeding, naproxen should only be used after careful medical benefit-risk assessment.
What should be considered in children?
The active substance is not suitable for children under the age of twelve.
Warnings and Precautions
- When taking antidiabetics, a precautionary measure of blood glucose is recommended.
- Medical history is required for high blood pressure and / or mild to moderate discomfort-causing cardiac muscle weakness, as the drug may cause tissue fluid retention (edema).
- Prolonged use of the drug may cause headaches that should not be treated by increased doses.
- Reactivity may be reduced after taking this drug.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.