Moxifloxacin contraindications and warnings


Following is information on contraindications to the use of moxifloxacin in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should moxifloxacin not be used?

In case of hypersensitivity to moxifloxacin or other gyrase inhibitors (such as ciprofloxacin, norfloxacin, levofloxacin), reuse should not be allowed.

Patients who have had tendinitis or tendon rupture during previous treatment with gyrase inhibitors should also not receive moxifloxacin. Due to possible cartilage damage, this also applies to children and adolescents in the growing age. Furthermore, pregnant women and nursing mothers should not be treated with moxifloxacin.

Patients with hepatic dysfunction or increased blood levels in the liver (transaminase elevation five times normal) should also not receive moxifloxacin. In addition, in case of disruption of minerals in the blood (such as low potassium) of a Moxifloxacingabe be foreseen.

Furthermore, the drug should not be used in known heart conditions such as heart failure (with reduced output), slow heartbeat (bradycardia), or prolonged heartbeat interval (long-QT syndrome). Even with a congenital glucose-6-phosphate dehydrogenase deficiency (metabolic disease) should no Moxifloxacingabe done.

Special medical care is appropriate for patients who are prone to cardiac arrhythmia or who have a history of heart attack. In these cases, a careful risk-benefit assessment by the doctor and also a regular monitoring is required.

Patients with mental health problems, seizure tendencies (epilepsy) or other brain diseases should also be treated with reluctance to use gyrase inhibitors. Depending on the extent and severity of the previous illness, the doctor will decide on a moxifloxacin administration individually.

What should you watch out for during pregnancy and lactation?

Pregnant women should not receive moxifloxacin. About the application during this time is not sufficient knowledge. Moxifloxacin passes into breast milk. Therefore breastfeeding mothers should also not be treated with this drug.

What should be considered in children?

Due to possible cartilage damage, children and adolescents should not receive moxifloxacin in growth (up to the age of 18 years).

Warnings and Precautions

  • In case of severe diarrhea during treatment, a doctor must be consulted.
  • There is an increased photosensitivity of the skin through the drug, which makes sun protection unnecessary. It is not recommended to visit the tanning beds during treatment.
  • Therapy must be discontinued in the case of pain or inflammation of the tendons.
  • In case of cardiac arrhythmia (particularly at risk are older people and women) it is necessary to discontinue therapy.
  • If you have vision problems, you should consult an ophthalmologist.
  • If the patient notices strong foaming urine during or after treatment with the drug, the doctor should check the kidney function.
  • Patients with a sugar-utilization disorder (glucose-6-phosphate dehydrogenase deficiency) should not take the medicine.
  • At the first sign of severe skin reaction or inflammation of the liver (fever, weakness, increased tendency to bleed, jaundice) discontinue treatment and consult the physician.
  • It can come on first use violent allergic reactions. Then the drug should not be used again.
  • The drug may cause exacerbation in Myasthenia gravis patients.
  • The drug is not suitable for children and adolescents under the age of 18 years.
  • The ability to react as well as the vision can be impaired, it can lead to short fainting. This may make operating machinery and driving a car dangerous.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.