Mirena side effects

What side effects can levonorgestrel have?

Below you will find the most important information about possible known side effects of levonorgestrel.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the side effects in nature and frequency (eg, tablet, spray, ointment) may be different depending on the dosage form of a drug.

When taken in low doses (“mini pill”)
Very common side effects:
spotting, bleeding, cycle irregularities.

Common side effects:
reduced sex drive, depressive moods, headache, dizziness, nervousness,

Uncommon side effects:
blotchiness on the face (chloasma), water retention in the tissue.

Rare side effects:
Incompatibility of contact lenses, increase in body hair, skin diseases, vaginal discharge, weight change.

When taking in high doses (“morning after pill”)
Very common side effects:
headache, nausea, pelvic pain, regardless of the rule occurring bleeding, fatigue.

Common side effects:
Dizziness, diarrhea, vomiting, menstrual period more than seven days late, inter-bleeding, spotting, tightness of the chest.

Very rare side effects:
general abdominal pain, rash, hives, itching, pelvic pain, menstrual pain, facial swelling.

Special features:
Temporarily there may be irregularities in the menstrual period; For most women, however, she uses the expected appointment within seven days. If the next menstrual period is more than five days overdue, a pregnancy must be excluded.

After taking a high dose of levonorgestrel for contraception following unprotected intercourse, diarrhea may occur.

When used in intrauterine devices (“spiral”)
Very common side effects:
headache, abdominal pain, pelvic pain, change in the menstrual period (too strong, too weak, spotting, occasional or missing bleeding), vaginal inflammation, discharge.

Common side effects:
Depressive mood, depression, migraine, nausea, acne, overheating, back pain, uterine or ovarian infections, ovarian cysts, menstrual pain, chest pain, intrauterine device expectoration (complete and partial) .

Occasional side effects:
hair loss, brown skin patches on the face, darkening of the skin.

Rare side effects:
Piercing the uterus.

Side effects of unknown frequency:
Hypersensitivity reactions (including rash, hives
and facial swelling).

Special features:
In many cases, lubrication and intermenstrual bleeding after a few months of use (mini pill or spiral) after.

After the onset of an intrauterine device, convulsive abdominal pain and spiral ejection often occur.

During use, the risk of ectopic pregnancy (pregnancy outside the uterus) is slightly increased. In the absence of menstruation and abdominal pain should therefore be a medical examination. The possibility of a liver tumor should also be considered.

At the first signs of venous disease due to blood clot formation (thrombosis), sudden onset of migraine or unusually severe headache, acute visual disturbances of any kind, severe depression or significant liver function disorders, treatment with levonorgestrel should be discontinued.

What interactions does levonorgestrel show?

Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).

There is no known interaction with other medicinal products when using the active substance in the form of an intrauterine device. The following interactions are possible when taking the active ingredient as a tablet.

When levonorgestrel is taken, substances that activate the degrading enzyme system can accelerate the degradation of levonorgestrel and diminish its effects. These include: antiepileptic drugs (such as carbamazepine, primidone, barbexaclon, lamotrigine or phenytoin), barbiturates, antibiotics (such as ampicillin, tetracyclines, rifabicin and rifabutin), griseofulvin (active ingredient for the treatment of fungal infections), acitretin (remedy for psoriasis), St. John’s Wort and the antiviral agents ritonavir and nevirapine.

Special attention should be given to this reduction in the effectiveness of emergency contraception: If one of the aforementioned active substances has been taken up to four weeks before the use of levonorgestrel, it may not be possible to achieve the reliable usual dosage of 1.5 milligrams acts. The doctor will therefore insert a copper coil in such a situation. This can be used for up to five days after unprotected sexual intercourse. If this is not possible, the dose for emergency contraception should be doubled to 3 milligrams of levonorgestrel. Ulipristal (brand name Ellaone) is not an alternative, as its effectiveness is even more attenuated by the above-mentioned substances.

Co-administration of medicinal charcoal will affect the absorption of the drug into the body.

Levonorgestrel may influence the efficacy of oral hypoglycaemic agents as well as those of insulin. Dose adjustments may be required.

Potential Mirena side effects may include: