About Mirena

4.0 rating based on 190 ratings
Rating: 4.1 Reviews: 190
About Mirena

Levonorgestrel is used to prevent pregnancy (“pill”, “contraceptive pill”). The active substance is particularly suitable for women who do not want to use estrogen-progestagen combinations for contraception or who are not allowed to take estrogens due to illness. Since the active ingredient does not affect milk production, it can also be used during breastfeeding.

What is the purpose of this ingredient?

  • thicken cervical mucus
  • block male sperm cells to the uterus
  • prevent nesting of a fertilized egg into the uterus
  • Prevent Pregnancy

This is how Levonorgestrel works

Below you will learn more about the fields of application and the mode of action of levonorgestrel.
Please also read the information on the drug groups progestins, contraceptives, sex hormones, to which the active ingredient levonorgestrel belongs.

Areas of application of the active substance levonorgestrel

Levonorgestrel is used to prevent pregnancy (“pill”, “contraceptive pill”). The active substance is particularly suitable for women who do not want to use estrogen-progestagen combinations for contraception or who are not allowed to take estrogens due to illness. Since the active ingredient does not affect milk production, it can also be used during breastfeeding.

The prerequisite for reliable contraception is the daily intake of a levonorgestrel-containing tablet at about the same time of the day. If this time is exceeded by more than three hours, the contraceptive effect is no longer guaranteed and on the following 14 days, additional non-hormonal measures to prevent pregnancy necessary. Also, nausea and vomiting as well as severe diarrhea may affect the efficacy of levonorgestrel.

Another form of contraceptive protection is a levonorgestrel-containing intrauterine device. Such an insertion system, also called a spiral, is made of plastic and is inserted into the uterus. It continuously releases small amounts of the active substance over a period of up to five years and prevents pregnancy with high reliability during this time.

Furthermore, a single dose of high dose of the active ingredient can prevent pregnancy within 72 hours of unprotected sexual intercourse. The reliability is greater, the less time has passed since sexual intercourse. Since the body is heavily burdened by the high hormone dose, this type of contraception should be limited to emergency situations.

In combination with an estrogen, levonorgestrel is also used to prevent pregnancy (for example, ethinylestradiol and levonorgestrel) and, in addition, such combinations can alleviate cycle disturbances and discomfort.

For the following application areas of Levonorgestrel , in-depth information is available:

  • contraception
  • Cycle Disorders and Discomfort

Mode of action of levonorgestrel

Levonorgestrel is an artificially manufactured hormonal drug. It is assigned to the group of progestagens for prevention and can be used as a mini-pill or intrauterine pessary (spiral). The drug thickens the mucus in the cervix, so male sperm can not enter the uterus. Furthermore, it changes the structure of the uterine lining so that a fertilized egg can not implant itself.

High dose levonorgestrel may also prevent pregnancy after unprotected sex (“morning after pill”). In this case, the drug suppresses imminent ovulation and prevents an already fertilized egg from intercalating and growing in the uterine lining. If the implantation has already taken place at the time of ingestion, levonorgestrel can no longer prevent the pregnancy since it does not have an abortive effect.

Potential Mirena side effects may include:

Mirena used to treat the following diseases:

  1. Danielle C. McDonald says:
    5.0 rating

    I’ve had Mirena for 16 months now. I had a lot of pain on insertion although I had my baby 1 year earlier. I could not leave the practice for 2 hours, because I could not drive a car in pain, I was in a real state of illness after insertion. Then came 6 months with the worst spotting …. without pause. Not just when I should have had my days. I also had that. Then I want to let things pull me, had an appointment already, and the bleeding were gone. Nice, I thought to myself. I then had 2 months rest, no bleeding, no complaints. Then I got stomachache left down, constipation and increased. It could not come from the spiral, I was told. But I did not change anything else in my life. After a long back and forth, a larger ultrasound was made and found a cyst on the left ovarian. Aha. Ok, wait and check in 3 weeks. There she was gone, the stomachache too. The next case was stomachache on the right, again to the doctor, a mini cyst on the ovary. Then followed by 4 months of permanent ache on the left, always the same cyst or a new one each time? Nobody knew. Recently, I’ve gotten hormones to the spiral to, orally, to see if the cyst goes away, but has not worked out. Then last week I wanted to have the spiral finally removed, but it did not work out because after 16 months the return button was gone. 3 Painful attempts to fetch her so failed. Tomorrow evening I get a short anesthetic to get rid of the part. I would like to take the pill again which I have tolerated well 15 years ago. Oh yes, my migraine has gotten better under Mirena, but the meds I’ve always taken did not work anymore. I hope that everything starts again tomorrow as it used to be, so that I can take my migraine medicines successfully again. And depressive moods and anxiety had also increased during Mirena. I would never recommend her if somebody got on well with the pill.

  2. Dorothy L. Edelson says:
    5.0 rating

    My experiences with Mirena have only become clear to me since my last insertion (third time at age 45). Only through the strong pain after pulling the old and simultaneously inserting the new spiral, I’ve googled a bit. And now I feel so stupid not to have thought earlier that my many complaints could come from the Mirena. These include frequent mild nausea (usually in the morning), breast tenderness (very painful), frequent headaches, back pain, a dripping nose all winter, always some water in the legs. But worst of all is my mood swings, I would call it depression. I’m always tired and every evening invitation is the horror for me because then I can not sleep early. Today I was with my doctor and wanted to remove the Mirena, she wrote me antidepressants and said I should try it first. The complaints could not possibly come from the Mirena … well, I let myself be talked over again and I think I’ll take things differently now. Since we certainly do not want any more children and I’m already 45, my partner could be sterilized and then I can remove the spiral. In any case, I can only advise against the Mirena, although it is very safe and relatively inexpensive. I’m sure I will not take the antidepressants, this is only symptom control, no cause-fighting.

  3. Pamela A. McEwen says:
    5.0 rating

    Mirena for Pain (acute)

    Hello, have read your reports and unfortunately I am also a hormone spiral Mirena negative case. My FA had recommended the spiral as totally safe and without any side effects. Hardly any menstrual bleeding, etc., anyway, everything should be totally great. Of course, I relied on this statement and got the spiral inserted. As soon as the spiral was inserted, everything went different than great. I had from the first day, and every day at the same time, pain in the abdomen and every day as massive as labor at a birth. The FA said this will happen eventually. Does not have it! After several weeks of massive depression, we decided to remove the coil. Thank god, I’m the los. At that time my mother had remarked, child it is a hormonal spiral, so what, I thought. But what I did not realize was, every woman gets a different contraceptive pill prescribed. When hormone spiral every woman gets the same dose, at least I was not asked for hormone sizes then. I think that every woman should be protected with the hormonal spiral, therefore, the maximum is set for all women. But that is not healthy, at least not for women who have lower hormone levels and therefore can not be exposed to this elephant dose. L.G.B.

    Side effects: Depression; Abdominal pains
  4. Martha K. Cotton says:
    5.0 rating

    I have Mirena on recommendation of my gynecologist three months after the birth of my daughter used. Had previously prevented with a hormone rod in the upper arm. And before that, for years, the minipill was taken. After the onset had almost 8 months to do with spotting and back pain. Then everything was okay. Until about half a year, chest pain, constant back pain, sometimes stronger, sometimes weaker, loss of libido, over time weight gain 6 kilos in total, are abdominal pain last week, digestive problems, constant fatigue, fatigue, strong feelings of aggression, anxiety, sweating, permanent headache, Dizziness …. and and at the moment I do not remember what to do. The constant fear and the inner restlessness are unbearable. I have made an appointment today with the gynecologist and will let me pull the Mirena. the appointment is only on the 24th must see if I can get any homoeopathic remedies. Nice for the women who tolerate Mirena. Through my many searches on the Internet, I am convinced that I am not one of the women who tolerate Mirena. If my gynecologist had better advised me on the side effects at the time, I definitely would not have opted for Mirena!

  5. Julie J. Martin says:
    4.5 rating

    First, no side effects. Later sleep disorders, ever-increasing depression and above all anxiety. Loss of libido. Doctor said that this is not related to Mirena, but premature menopause and have actually prescribed something against menopausal symptoms. As a result, I let the Mirena go against the will of the doctor and changed the doctor. That was 2003! The symptoms disappear very soon – no more of fear, depression and libido loss !! A completely different quality of life!

  6. Carol D. Fitzpatrick says:
    4.0 rating

    Headache, migraine attacks, permanent bleeding (21-23 days bleeding – then 6-7 days bleeding), severe to very severe abdominal pain at onset of bleeding (1-2 days), mild to moderate pain in the abdomen without bleeding, depressive disorders, mood swings, loss of libido , Lack of concentration, hair loss, listlessness

  7. Leisha Q. Thomas says:
    2.5 rating

    In the last 5 years I have increased about 25 kg. The doctor says that is not due to Mirena. However, I’m always hungry for sweets and I’m not sure if it’s not because of Mirena.

    Side effects: Increase in weight