About Metoprolol

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Rating: 3.2 Reviews: 84
About Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

What is the purpose of this ingredient?

  • Lower blood pressure for high blood pressure
  • relieve the heart after heart attack
  • Prevent migraine attacks
  • by relieving the heart from heart attacks
  • widen the coronary arteries and thereby promote the circulation of the heart muscle
  • Slow heartbeat

This is how Metoprolol works

Below you will learn more about the fields of application and the mode of action of metoprolol.
Please also read the information on the drug groups beta-blockers, antihypertensives, to which the active ingredient metoprolol belongs.

Applications of the active substance Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

In addition, metoprolol is prescribed for heart disease associated with inadequate oxygenation of the heart muscle (myocardial insufficiency) and circulatory disorders of the coronary heart disease (coronary heart disease). In this context, metoprolol is used in stable, not causing discomforting angina pectoris.

Another area of use of the drug is cardiac arrhythmia associated with too rapid a heartbeat. Metoprolol can have a beneficial effect on these cardiac arrhythmias because it slows down the heartburn.

Metoprolol continues to be used in the acute treatment of heart attack to relieve the heart. After a heart attack, the drug is used preventively in long-term treatment to reduce the risk of further incidents leading to sudden cardiac death.

Beyond the potential of cardiovascular disease, metoprolol is the first choice for the prevention of migraine. When taken regularly, it causes the frequency and severity of seizures to decrease.

For the following application areas of Metoprolol , in-depth information is available:

  • arrhythmia
  • infarction
  • migraine
  • Hypertension
  • heart failure
  • Angina pectoris
  • Cardiovascular Disease

Mode of action of Metoprolol

The active substance metoprolol is a beta-blocker with so-called beta-1-selective properties. This means that it acts primarily on the beta-1 receptors. Beta-1 receptors are special binding sites of the sympathetic fibers of the autonomic nervous system, which are normally activated by the body’s own messengers adrenaline and norepinephrine. Metoprolol displaces these endogenous messenger substances at the receptors and thus suppresses their effect.

At the beta-1 receptors of the heart, the drug slows down the transmission of electrical impulses to the conduction system. This lowers the number of heartbeats and the amount of blood pumped during each heartbeat (heartbeat volume). As a result, the blood pressure drops significantly and the heart is calmed and thus relieved when the stress level is too high.

At beta-1 receptors in the kidneys, metoprolol cushions the release of the blood pressure enhancing hormone renin. So the blood pressure is additionally lowered.

The efficacy of metoprolol in preventing migraine attacks is directly attributed to inhibition of beta-receptors in the brain but is not fully understood.

Metoprolol is almost completely taken from the gastrointestinal tract after taking it as a tablet. However, metoprolol is subject to a pronounced so-called “first-pass effect”. This means that about half the amount of active ingredient is already degraded in the liver, before it is distributed through the bloodstream in the body and the site of action, for example to the heart, and can act there. The recommended dosage already takes this effect into account.

Potential Metoprolol side effects may include:

Metoprolol used to treat the following diseases:

  1. Jerry J. Silver says:
    4.0 rating

    Metoprolol for High blood pressure

    Very heavy daytime sleepiness and dizziness after taking 10 mg of cetirizine the night before. The side effects only appear after about 5 to 8 hours and last about 10 to 15 hours. The antiallergic efficacy is very good.

    Side effects: Fatigue
  2. Carroll M. Yelverton says:
    4.0 rating

    Metoprolol for High blood pressure

    The drug was combined with AMILORIDcomp. and Metoprolol 100mg. Very strong dizziness, especially orthostatic dizziness, constant nausea and constant headache. Chest pain and dramatic decrease in visual acuity. After discontinuing the drug, everything was normal.