About Metoprolol

3.0 rating based on 85 ratings
Rating: 3.2 Reviews: 85
About Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

What is the purpose of this ingredient?

  • Lower blood pressure for high blood pressure
  • relieve the heart after heart attack
  • Prevent migraine attacks
  • by relieving the heart from heart attacks
  • widen the coronary arteries and thereby promote the circulation of the heart muscle
  • Slow heartbeat

This is how Metoprolol works

Below you will learn more about the fields of application and the mode of action of metoprolol.
Please also read the information on the drug groups beta-blockers, antihypertensives, to which the active ingredient metoprolol belongs.

Applications of the active substance Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

In addition, metoprolol is prescribed for heart disease associated with inadequate oxygenation of the heart muscle (myocardial insufficiency) and circulatory disorders of the coronary heart disease (coronary heart disease). In this context, metoprolol is used in stable, not causing discomforting angina pectoris.

Another area of use of the drug is cardiac arrhythmia associated with too rapid a heartbeat. Metoprolol can have a beneficial effect on these cardiac arrhythmias because it slows down the heartburn.

Metoprolol continues to be used in the acute treatment of heart attack to relieve the heart. After a heart attack, the drug is used preventively in long-term treatment to reduce the risk of further incidents leading to sudden cardiac death.

Beyond the potential of cardiovascular disease, metoprolol is the first choice for the prevention of migraine. When taken regularly, it causes the frequency and severity of seizures to decrease.

For the following application areas of Metoprolol , in-depth information is available:

  • arrhythmia
  • infarction
  • migraine
  • Hypertension
  • heart failure
  • Angina pectoris
  • Cardiovascular Disease

Mode of action of Metoprolol

The active substance metoprolol is a beta-blocker with so-called beta-1-selective properties. This means that it acts primarily on the beta-1 receptors. Beta-1 receptors are special binding sites of the sympathetic fibers of the autonomic nervous system, which are normally activated by the body’s own messengers adrenaline and norepinephrine. Metoprolol displaces these endogenous messenger substances at the receptors and thus suppresses their effect.

At the beta-1 receptors of the heart, the drug slows down the transmission of electrical impulses to the conduction system. This lowers the number of heartbeats and the amount of blood pumped during each heartbeat (heartbeat volume). As a result, the blood pressure drops significantly and the heart is calmed and thus relieved when the stress level is too high.

At beta-1 receptors in the kidneys, metoprolol cushions the release of the blood pressure enhancing hormone renin. So the blood pressure is additionally lowered.

The efficacy of metoprolol in preventing migraine attacks is directly attributed to inhibition of beta-receptors in the brain but is not fully understood.

Metoprolol is almost completely taken from the gastrointestinal tract after taking it as a tablet. However, metoprolol is subject to a pronounced so-called “first-pass effect”. This means that about half the amount of active ingredient is already degraded in the liver, before it is distributed through the bloodstream in the body and the site of action, for example to the heart, and can act there. The recommended dosage already takes this effect into account.

Potential Metoprolol side effects may include:

Metoprolol used to treat the following diseases:

  1. Dominic M. Jenkins says:
    3.0 rating

    Metoprolol for High blood pressure

    Who has the same side effects from ramipril (2.5mg) I am 45 years, 172 cm tall and weigh 72 kg, BMI 24, athletic (daily 60 min cycling or walking) In April of this year I had to go to a hospital, because of my spine , When ECG I was asked if I had ever had a heart attack, which I said no. The next day I was given a heart catheter and attested that I did not have an infarct, but …. Please read the result in the attachment. Then I was treated by the family doctor with metoprolol and ramipril and had pretty much all the side effects that are in the leaflet. Metoprolol was replaced by Nebilet in July. Since then, the side effects are lower, but it has adjusted to a daily irregular heart pressure and a heart piercing around the heart. The main pain is about four fingers above the left nipple, a stabbing pain that lasts about ten minutes and gradually fades away. Sometimes it also starts at the top of the heart and stops after 360 degrees. It means that the pain will march around the heart once within several hours, once it is more of a pressure, the next moment is a sting. Since my last visit to the cardiologist, to whom I have again told everything in detail, I should now additionally take morning and evening 1 PENTALONG tablet. Five months ago, I did not have anything yet and now I swallow six tablets daily. Is that the last word of wisdom? Where does that come from? Is it dangerous? Is it the medication? Are there any alternatives to my medications that will fix the problem? Unfortunately, since I have to take the medication, I do not feel well at all and do not dare to burden myself with cycling like I did before, because I’m afraid that I’m trying too hard and I suffer a heart collapse.

    Side effects: Heart ache
  2. Nathan L. Cooper says:
    2.5 rating

    Metoprolol for Heart attack

    Can not be worse, trepidation and uncontrollable chest pain on sternum, feels like re-infarction. Weight loss and constant intoxicating cough. Causes panic attacks.

  3. James S. Gordon says:
    4.0 rating

    Metoprolol for Heart attack

    Mostly on hot days and from time to time even on cool days, I feel uphill a pressure about 4 fingers above the heart associated with shortness of breath. I also had a constant cough and I am always tired. My doctor says I simulate because the investigations are all right.

  4. Anna V. Biggs says:
    3.5 rating

    Metoprolol for High blood pressure

    For more than 15 years I have had to swallow beta-blockers because of high blood pressure and migraine prophylaxis. Beloc-zok and Metoporol 50 have been prescribed for some time. The initial dose was one tablet and for about 2 years I was supposed to take 2 tablets. Since I’ve been taking beta-blockers, I’ve been steadily increasing. Since the dose was increased, I took about 10kg to predominantly on the stomach, which looks very ugly. My eating habits have been drastically reduced, no snacking, no alcohol (because of the migraine anyway almost taboo), low fat and small portions. I even try to do sports, but the weight goes up! Massive sleep disorders, restless legs, muscle spasms, listlessness, depression and sexual listlessness are added to this weight problem. These complaints were u. a. kept as menopause consequences. On the leaflet there is no indication. Unfortunately, there is probably no alternative.

  5. Robert K. Johnson says:
    3.0 rating

    Metoprolol for High blood pressure

    Since taking Vote 20 mg, I have problems with dizziness, muscle twitching, muscle cramps, tiredness, tingling in the arm and hand on the right, no more strength in the arms and hands. It could also be that come from Votum my Errektionsschwierigkeiten. I have now dropped vote 20 mg and hope that I feel better then.

  6. Ronald D. Gaffney says:
    4.5 rating

    Metoprolol for High blood pressure

    The experience with both drugs (metoprolol + enalapril) was and is catastrophic. Pronounced side effects: Total sleep disorders due to panic dreams, forgetfulness, high depression, massive confusion, memory loss, severe balance disorders, nervousness, aggression and loss of control, in short: total personality change. Weight loss in 14 days 8 Kg. I have to go into psycholigical treatment. Symptoms persist even after the medication has been discontinued.

    Side effects: Nervousness; Sleep disorders
  7. Herbert A. Ross says:
    3.0 rating

    Metoprolol for High blood pressure

    Side effect Metoprolol Dizziness, weight gain, heavy legs (as with a cold) Side effect Ramipril Dizziness, dry cough, edema on the wrists Side effect Rasilez some days Red and swollen face Despite all the medication does not reach a constant blood pressure reduction.

  8. Martha R. Dorsey says:
    1.5 rating

    Metoprolol for Heart rhythm disturbances; High blood pressure

    Since reading the reports of the side effects of other patients, I find that they agree with some of my symptoms: sometimes dizziness, suppose. Weight gain despite eating little (168 cm, 79-82 kg). I’m 61 years old and push the sometimes significant sweats (the water is just so running) always on the menopause, so do the doctors. Maybe this is due to the use of Metoprolol . The fatigue and depression as well as drive and insomnia, lightning in front of the eyes can certainly, lt. other statements, even come from it. Maybe I should change the medication. Unless the cashier pays. Or do I have to pay?

  9. Stacey R. Killian says:
    3.5 rating

    Metoprolol for High blood pressure

    Since the onset of taking Aggrenox, visual disturbances are very common and the sight of my eyes has deteriorated so rapidly in the short time that new glasses are needed. I have told several doctors, but no one wants to see a connection. However, after I found articles on the Internet that confirm a connection, I contacted the manufacturer, who denied everything.

    Side effects: Blurred vision
  10. Kathleen D. Silvers says:
    4.5 rating

    Metoprolol for High blood pressure

    I got the medication for hypertension and so I get a bit calmer nervously, get prescribed. I had a lot of side effects that were all considered psychologically by three different doctors. Now that I have skipped the beta-blocker on my own, I can say with certainty that it was not psychic because I am getting better and better with discontinuing the drug. My side effects with Metoprolol were: Fear (extremely, I was already thinking about switching jobs because I was increasingly frightened of working with chemicals and gases (I work in a chemistry lab), which was reversed by stopping the medication dizziness, inner restlessness, respiratory misfire at night, greatly slowed and complicated thinking, fatigue, lack of energy, arrhythmia. My blood pressure was not better with beta blocker than now.

  11. Robert T. Scott says:
    2.0 rating

    Metoprolol for High blood pressure

    Good day, now I know that I often have difficulty breathing from metoprolol and the pulse often drops to 35 beats in one minute, which causes a great anxiety and then begins the heart hunt and the blood pressure increases very much. There is often a tingling sensation in the chest when the medication starts to work and I have to accept it. Most of the time, I also notice a fuss after taking Metoprolol, but it subsides after a while. Care must be taken that Metrobolol is taken with a calcium antagonist, as the pulse is slowed down and there are too many side effects. It is best to wait 30 minutes until you first take the other medication, as fewer side effects come into consideration.

  12. Consuelo E. Foster says:
    3.5 rating

    I have been taking metoprolol 47.5 for 3 days again. in the morning before breakfast a tablet! I have not taken them since 2009 and today I’m pretty flat …. dizziness, diarrhea, nausea or more fullness. sting in the chest and in the rib area. But I take everything in purchase this will not go away I will talk again with my artz!

    Side effects: Bloating; Diarrhea; Nausea; Dizziness
  13. Sandy J. Aranda says:
    4.5 rating

    Metoprolol for Depression; Heart rhythm disturbances

    Valdoxan, first night, barely able to endure migraines, dizziness, tremors, high pulse, internal freezing, nightmares, although I started with half Valdoxan 25mg. Thank god, otherwise I would not have taken it further. Bearable during the day, some headache, increased heart rate and mild hypertension. Tried to regulate blood pressure and pulse in the morning with half a metoprolol, small success. After 3 days, slight weight loss. Retained half the dose of Valdoxan 25 mg for a week, then increased it to a whole, because the mood was pretty depressive and I often had to cry. Some side effects disappeared, leaving dizziness, increased heart rate and low blood pressure after 2 weeks. Yesterday evening, at about 6.30 pm, I took half a metoprolol again, because the pulse was a little high, had a terrible night, almost as bad as the very first night, migraine, trembling. I hope that the trigger of this night was the evening intake of half metoprolol. Still afraid of tonight. Positive is, however, easy weight loss, no food cravings, only because I try to hold out. Maybe the side effects will disappear.

  14. Elizabeth T. Calvert says:
    2.5 rating

    Metoprolol for High blood pressure

    Meto-Isis taken 7 years, then get through the pharmacy Metoprolol, as the health insurance company Meto-Isis did not take. After 3 weeks there were tingling sensations on the face in the calves, drowsiness and the feeling of fainting. The family doctor has then switched back to Meto-Isis. The symptoms got worse and worse, in addition to panic attacks, blurred vision, drop in blood pressure, high blood pressure, dizziness and at the moment tachycardia.

  15. Suzanne R. Jackson says:
    4.0 rating

    Metoprolol for Heart rhythm disturbances; High blood pressure

    Drug moderately affects blood pressure. Pulse drops sharply (from 120 to 47). Constant tiredness, listlessness. Cold hands and feet, otherwise frequent sweating. Acts like a strong sedative. Subdued emotions, i. little excitement but hardly any joy. Tingling and muscle aches. Very unpleasant nightmares, the first time in your life tachycardia at night. Despite the cushioning occasionally muscle tremors and restlessness. Change the personality (from cheerful and spirited, but also anxious and excited to lahmarschig and lazy …) Nevertheless, too high a pulse is of course also extremely exhausting and certainly not healthy. I will continue to search, because this drug is a blow to the head with the hammer ;-))).