About Metoprolol

3.0 rating based on 86 ratings
Rating: 3.2 Reviews: 86
About Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

What is the purpose of this ingredient?

  • Lower blood pressure for high blood pressure
  • relieve the heart after heart attack
  • Prevent migraine attacks
  • by relieving the heart from heart attacks
  • widen the coronary arteries and thereby promote the circulation of the heart muscle
  • Slow heartbeat

This is how Metoprolol works

Below you will learn more about the fields of application and the mode of action of metoprolol.
Please also read the information on the drug groups beta-blockers, antihypertensives, to which the active ingredient metoprolol belongs.

Applications of the active substance Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

In addition, metoprolol is prescribed for heart disease associated with inadequate oxygenation of the heart muscle (myocardial insufficiency) and circulatory disorders of the coronary heart disease (coronary heart disease). In this context, metoprolol is used in stable, not causing discomforting angina pectoris.

Another area of use of the drug is cardiac arrhythmia associated with too rapid a heartbeat. Metoprolol can have a beneficial effect on these cardiac arrhythmias because it slows down the heartburn.

Metoprolol continues to be used in the acute treatment of heart attack to relieve the heart. After a heart attack, the drug is used preventively in long-term treatment to reduce the risk of further incidents leading to sudden cardiac death.

Beyond the potential of cardiovascular disease, metoprolol is the first choice for the prevention of migraine. When taken regularly, it causes the frequency and severity of seizures to decrease.

For the following application areas of Metoprolol , in-depth information is available:

  • arrhythmia
  • infarction
  • migraine
  • Hypertension
  • heart failure
  • Angina pectoris
  • Cardiovascular Disease

Mode of action of Metoprolol

The active substance metoprolol is a beta-blocker with so-called beta-1-selective properties. This means that it acts primarily on the beta-1 receptors. Beta-1 receptors are special binding sites of the sympathetic fibers of the autonomic nervous system, which are normally activated by the body’s own messengers adrenaline and norepinephrine. Metoprolol displaces these endogenous messenger substances at the receptors and thus suppresses their effect.

At the beta-1 receptors of the heart, the drug slows down the transmission of electrical impulses to the conduction system. This lowers the number of heartbeats and the amount of blood pumped during each heartbeat (heartbeat volume). As a result, the blood pressure drops significantly and the heart is calmed and thus relieved when the stress level is too high.

At beta-1 receptors in the kidneys, metoprolol cushions the release of the blood pressure enhancing hormone renin. So the blood pressure is additionally lowered.

The efficacy of metoprolol in preventing migraine attacks is directly attributed to inhibition of beta-receptors in the brain but is not fully understood.

Metoprolol is almost completely taken from the gastrointestinal tract after taking it as a tablet. However, metoprolol is subject to a pronounced so-called “first-pass effect”. This means that about half the amount of active ingredient is already degraded in the liver, before it is distributed through the bloodstream in the body and the site of action, for example to the heart, and can act there. The recommended dosage already takes this effect into account.

Potential Metoprolol side effects may include:

Metoprolol used to treat the following diseases:

  1. Cindy J. Sandlin says:
    3.0 rating

    Metoprolol for Migraine; Heart rhythm disturbances; High blood pressure

    For about 1.5 years I have an increasing headache, in the spring came then the hypertension and a slight tachycardia – I have also in a longer period of rest (at night, etc.), etc. felt an increased heart rate. Lastly, I had a headache every 3 days, regardless of whether I worked, it was weekend, or it was morning or evening. I was prescribed beta-blockers (metoprolol) and headache tablets (migraine tone). I had to take the beta-blockers once in the morning and once in the evening, the painkillers only when needed. Hypertension and tachycardia have decreased and have temporarily returned to normal. Also the headache attacks came less often. Around the same time, the hay fever period came and I had to take because of various symptoms (itching in the throat, sneezing, etc.) an antiallergic. In the meantime, I have also taken magnesium, as I got calf cramps and these lasted some days. In the meantime, however, I have discontinued the magnesium dragees and paused for a few days, then taken again. For 2 weeks I no longer take the dragees, but will start taking them again. For more than 2 years I also occasionally have the problem that my hands swell for no reason (only the palms of my hands), become red and hot and extremely itchy. Systral, Fenistil, Soventol & amp; Co., but not always. Also, I have long had the problem that my feet are constantly cooking – even in winter. Outwardly there is nothing to feel, they also like to feel cold, but inside I have the feeling that the feet are cooking. Most of my feet are not covered by the blanket when sleeping, otherwise I could not fall asleep. In summer, I put my feet in a bucket of water so that I can fall asleep at all … 4 weeks ago I had an MRI scan because of the headache, it was found that the findings are inconspicuous. For 3 weeks, I have not taken the beta-blockers, since the headaches have occurred more frequently. Blood pressure and heart rate have also risen again. Now I am in 3 days before a blood test and an ultrasound of the thyroid gland before. For about 2 weeks I also have the feeling that my lower legs and feet are swollen, since 3 days this has become extreme. In addition, I have a slight itching on top of the space between the toes for these two weeks – as the person is, of course I scratched and a place has risen. Yesterday, the area around this wound went extremely off (like a bruise) and blushed. Today my feet feel even swollen, my ankle is also much lower. I then just with one finger pressed sideways on the foot – as a dent has remained. Unfortunately, today is only Saturday, but I will tell my family doctor at the latest on Tuesday morning at the appointment of the swollen feet – at the latest!

  2. Elaine L. Chavez says:
    3.5 rating

    Metoprolol for Depression; Heart rhythm disturbances; High blood pressure

    Before irritable bowel, with the use of metoprolol permanent constipation, evening calf pain. Have the drug discontinued, digestion works again, calf pain has stopped. Blood pressure levels continued to increase sporadically, pulse rate continued to remain almost permanent tachycard (even when taking metoprolol, blood pressure was still elevated and pulse rate always in the tachycarden area).

  3. John M. Stinnett says:
    3.0 rating

    Metoprolol for Diabetes mellitus type ii; Atrial fibrillation; Heart rhythm disturbances

    to ASS Protect 300, I take instead of Marcumar I do not tolerate, carry the Riesiko … amitriptyline, calms me something takes me a little afraid of Vorhafflimmern … now without insulin I could not live anymore but it is not so easy to measure at every meal, inject and then it does not matter, because cortisone that I need for the treatment of colitis makes everything unpredictable again … The sentence Marcumar anybody who my doctors can handle so loud, I can no longer hear muscle cramps , Muscle failure, dyspnea, laryngeal swelling, dizziness, nausea, weakness, heatwaves … all came with the use of Marcumar … after weaning, a large part of the side effects disappeared, a renewed trial yielded the same result, but not all that was bad with the medication Side effects disappeared …

    Side effects: No side effects
  4. Jessica H. Burke says:
    5.0 rating

    Metoprolol for Fat metabolic disorders

    My family doctor prescribed Metroprolol for stress reduction. I asked my doctor if the beta-blockers had any side effects, and my doctor waved me off and told me that many athletes take these beta-blockers. Unfortunately, after many years, I realized that my Trigliceride values have risen sharply for inexplicable reasons, and unfortunately I have become emotionally cold. After getting an itchy rash on my stomach, back and arms, I set my beta blockers in consultation with the doctor. My emotional coldness has decreased and the Trigliceride are still being tested with the blood.

  5. Laura J. Lawrence says:
    3.5 rating

    Metoprolol for Stomach protection; Heart rhythm disturbances

    Naproxen (2 x daily 500mg) and paracetamol (3 x daily 500mg) cause stomach problems despite taking pantoprazole (1 x daily 40mg)

  6. Deborah H. Sutherland says:
    1.5 rating

    Metoprolol for Diabetes mellitus type ii; Stomach protection; Thyroid function under; Sleep disorders; Cholesterol value increase; High blood pressure

    On the whole, I tolerated the medis very well. Except when my sugar is high, then it is already before me dizzy is very much. But I generally find that the drugs today are better tolerated than before. Also in things insulin has done a lot. Since I have since 1985 diabetes type mody 3 and insulin resistant it is not always easy to adjust myself with insulin is just an eternal process. since 1987 I have colitis ulcerosa and since 2002 I am completely stopped by the colitis. I am very happy about that.

    Side effects: No side effects
  7. Mark L. Storm says:
    4.5 rating

    Metoprolol for Sleep disorders; Cholesterol value increase; High blood pressure

    5 years ago I came to the neurologist with depression and mild anxiety disorders. I should start right away with the final dose of 20 mg. It took almost 3 weeks until I was able to work so well through the tbl. That I was able to work. After a long time, I have the anxiety disorder under control, which I can not say about the rest of my life! I have been tired, chipped and listless since taking Paroxetine and Doxepin. What’s more, in the first 1 1/2 years, I’ve gained a whopping 30 kg! You could literally watch as I’ve gotten fatter. Everyone raised me then, whether I was pregnant, which annoyed me in the long run totally annoyed. Even in my own family, I’m only bullied because of my overweight. I have tried many times to drop the paroxetine – but never worked! Already at 1/2 Tbl weiger per day it goes steeply downhill. I have no idea how long I still have to take the shit. My conclusion: I feel like I’m living in slow motion for 5 years … just tired, broken, powerless! In addition, 30 kg more on the rib and sex, I actually really net synonymous net.I wish all here a lot of strength u. Joie de vivre and do not despair …… everything will be alright !!!

  8. Brenda M. Bennett says:
    4.5 rating

    Metoprolol for Coronary heart disease; Cholesterol value increase; Heart rhythm disturbances

    Simvastatin brought the cholesterol levels to very good levels. Unfortunately, it almost got me in the wheelchair. Doctors ignore worries and concerns, trying to get me to take it back. For a year, I refuse. Etrezol is the same. Since I no longer take these medications, the value (for a healthy person) is in the normal range.

  9. Marvin A. Sims says:
    2.0 rating

    Metoprolol for Stomach protection; Cholesterol value increase; High blood pressure


    Side effects: Nausea
  10. Lucina R. Smith says:
    3.5 rating

    Metoprolol for Atrial fibrillation

    Morning dizziness, but after about 1 hour passes. Slight depression associated with the fact that I am now required to take medication. But the habituation has already occurred .. However, now begins the discipline. Because when there are no more symptoms to be observed, the brain has to work. With hello, take your tablets.

    Side effects: Dizziness
  11. Dorothy E. Melancon says:
    4.5 rating

    Metoprolol for Migraine

    Originally my migraine should be treated nevertheless my high blood pressure was to be treated in one stroke after long hesitation I took this drug only because the side effects are so strong but I was really helped my migraine which was already several times a week I could get a grip My high blood pressure was still there and got worse than better no idea but the doctors have not been under control

    Side effects: High blood pressure
  12. Lisa D. Hopkins says:
    3.5 rating

    After thirty years, the side effects become so pronounced that they are no longer reparable. Now the side effects I have: High blood pressure (167/86/71), palpitations-fast pulse, tinnitus, cold feet, itching ..

    Side effects: High blood pressure
  13. Christina T. Ford says:
    4.5 rating

    I take metoprolol for migraine and infarction prophylaxis only recently, the side effects are, I can only agree, not insignificant: Tiredness, listlessness, sweating and my depression came back. However, this may be related to the fact that I have a very low blood pressure by nature and a resting heart rate of 2 strong migraine attacks with aura per week: a normal libido, creativity, enjoyment of the beautiful things, inventiveness. Because of the depression, I’m back in treatment and I’m sure that the nausea and fatigue is still relativized a little. With weight gain I have so far no problems, I have rather decreased (less frustration than with migraine, and weight gain because of drugs is fast for me (with cortisol 15kg in 2 weeks)).

  14. Lee D. King says:
    2.5 rating

    Metoprolol succinate 98mg 1– led to heavy daytime fatigue after dose adjustment. After getting enough sleep (8 hours) he fell asleep several times on the way to work at a red traffic light. Listlessness, sadness!