About Metoprolol

3.0 rating based on 83 ratings
Rating: 3.2 Reviews: 83
About Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

What is the purpose of this ingredient?

  • Lower blood pressure for high blood pressure
  • relieve the heart after heart attack
  • Prevent migraine attacks
  • by relieving the heart from heart attacks
  • widen the coronary arteries and thereby promote the circulation of the heart muscle
  • Slow heartbeat

This is how Metoprolol works

Below you will learn more about the fields of application and the mode of action of metoprolol.
Please also read the information on the drug groups beta-blockers, antihypertensives, to which the active ingredient metoprolol belongs.

Applications of the active substance Metoprolol

Metoprolol is used in the treatment of hypertension, which has no organic causes (essential hypertension), and cardiovascular problems.

In addition, metoprolol is prescribed for heart disease associated with inadequate oxygenation of the heart muscle (myocardial insufficiency) and circulatory disorders of the coronary heart disease (coronary heart disease). In this context, metoprolol is used in stable, not causing discomforting angina pectoris.

Another area of use of the drug is cardiac arrhythmia associated with too rapid a heartbeat. Metoprolol can have a beneficial effect on these cardiac arrhythmias because it slows down the heartburn.

Metoprolol continues to be used in the acute treatment of heart attack to relieve the heart. After a heart attack, the drug is used preventively in long-term treatment to reduce the risk of further incidents leading to sudden cardiac death.

Beyond the potential of cardiovascular disease, metoprolol is the first choice for the prevention of migraine. When taken regularly, it causes the frequency and severity of seizures to decrease.

For the following application areas of Metoprolol , in-depth information is available:

  • arrhythmia
  • infarction
  • migraine
  • Hypertension
  • heart failure
  • Angina pectoris
  • Cardiovascular Disease

Mode of action of Metoprolol

The active substance metoprolol is a beta-blocker with so-called beta-1-selective properties. This means that it acts primarily on the beta-1 receptors. Beta-1 receptors are special binding sites of the sympathetic fibers of the autonomic nervous system, which are normally activated by the body’s own messengers adrenaline and norepinephrine. Metoprolol displaces these endogenous messenger substances at the receptors and thus suppresses their effect.

At the beta-1 receptors of the heart, the drug slows down the transmission of electrical impulses to the conduction system. This lowers the number of heartbeats and the amount of blood pumped during each heartbeat (heartbeat volume). As a result, the blood pressure drops significantly and the heart is calmed and thus relieved when the stress level is too high.

At beta-1 receptors in the kidneys, metoprolol cushions the release of the blood pressure enhancing hormone renin. So the blood pressure is additionally lowered.

The efficacy of metoprolol in preventing migraine attacks is directly attributed to inhibition of beta-receptors in the brain but is not fully understood.

Metoprolol is almost completely taken from the gastrointestinal tract after taking it as a tablet. However, metoprolol is subject to a pronounced so-called “first-pass effect”. This means that about half the amount of active ingredient is already degraded in the liver, before it is distributed through the bloodstream in the body and the site of action, for example to the heart, and can act there. The recommended dosage already takes this effect into account.

Potential Metoprolol side effects may include:

Metoprolol used to treat the following diseases:

  1. John M. Stinnett says:
    3.0 rating

    Metoprolol for Diabetes mellitus type ii; Atrial fibrillation; Heart rhythm disturbances

    to ASS Protect 300, I take instead of Marcumar I do not tolerate, carry the Riesiko … amitriptyline, calms me something takes me a little afraid of Vorhafflimmern … now without insulin I could not live anymore but it is not so easy to measure at every meal, inject and then it does not matter, because cortisone that I need for the treatment of colitis makes everything unpredictable again … The sentence Marcumar anybody who my doctors can handle so loud, I can no longer hear muscle cramps , Muscle failure, dyspnea, laryngeal swelling, dizziness, nausea, weakness, heatwaves … all came with the use of Marcumar … after weaning, a large part of the side effects disappeared, a renewed trial yielded the same result, but not all that was bad with the medication Side effects disappeared …

    Side effects: No side effects
  2. Jessica H. Burke says:
    5.0 rating

    Metoprolol for Fat metabolic disorders

    My family doctor prescribed Metroprolol for stress reduction. I asked my doctor if the beta-blockers had any side effects, and my doctor waved me off and told me that many athletes take these beta-blockers. Unfortunately, after many years, I realized that my Trigliceride values have risen sharply for inexplicable reasons, and unfortunately I have become emotionally cold. After getting an itchy rash on my stomach, back and arms, I set my beta blockers in consultation with the doctor. My emotional coldness has decreased and the Trigliceride are still being tested with the blood.

  3. Laura J. Lawrence says:
    3.5 rating

    Metoprolol for Stomach protection; Heart rhythm disturbances

    Naproxen (2 x daily 500mg) and paracetamol (3 x daily 500mg) cause stomach problems despite taking pantoprazole (1 x daily 40mg)

  4. Deborah H. Sutherland says:
    1.5 rating

    Metoprolol for Diabetes mellitus type ii; Stomach protection; Thyroid function under; Sleep disorders; Cholesterol value increase; High blood pressure

    On the whole, I tolerated the medis very well. Except when my sugar is high, then it is already before me dizzy is very much. But I generally find that the drugs today are better tolerated than before. Also in things insulin has done a lot. Since I have since 1985 diabetes type mody 3 and insulin resistant it is not always easy to adjust myself with insulin is just an eternal process. since 1987 I have colitis ulcerosa and since 2002 I am completely stopped by the colitis. I am very happy about that.

    Side effects: No side effects
  5. Mark L. Storm says:
    4.5 rating

    Metoprolol for Sleep disorders; Cholesterol value increase; High blood pressure

    5 years ago I came to the neurologist with depression and mild anxiety disorders. I should start right away with the final dose of 20 mg. It took almost 3 weeks until I was able to work so well through the tbl. That I was able to work. After a long time, I have the anxiety disorder under control, which I can not say about the rest of my life! I have been tired, chipped and listless since taking Paroxetine and Doxepin. What’s more, in the first 1 1/2 years, I’ve gained a whopping 30 kg! You could literally watch as I’ve gotten fatter. Everyone raised me then, whether I was pregnant, which annoyed me in the long run totally annoyed. Even in my own family, I’m only bullied because of my overweight. I have tried many times to drop the paroxetine – but never worked! Already at 1/2 Tbl weiger per day it goes steeply downhill. I have no idea how long I still have to take the shit. My conclusion: I feel like I’m living in slow motion for 5 years … just tired, broken, powerless! In addition, 30 kg more on the rib and sex, I actually really net synonymous net.I wish all here a lot of strength u. Joie de vivre and do not despair …… everything will be alright !!!

  6. Brenda M. Bennett says:
    4.5 rating

    Metoprolol for Coronary heart disease; Cholesterol value increase; Heart rhythm disturbances

    Simvastatin brought the cholesterol levels to very good levels. Unfortunately, it almost got me in the wheelchair. Doctors ignore worries and concerns, trying to get me to take it back. For a year, I refuse. Etrezol is the same. Since I no longer take these medications, the value (for a healthy person) is in the normal range.

  7. Marvin A. Sims says:
    2.0 rating

    Metoprolol for Stomach protection; Cholesterol value increase; High blood pressure

    SINVA: MUSCLE, BONE, MIER DOES THE WHOLE BODY PAIN ASS: EVERYTHING OK METROPOLOL: MORNING AFTER ACCEPTANCE CA 1.5 ST LATE PAIN AND EVIL UNTIL DAILY DAN SOMETHING BETTER, EVEN STRONG FEELING HAD IN MARCH 2006 HAD A 3-DAY GET MFG MANUEL JIMENEZ

    Side effects: Nausea
  8. Lucina R. Smith says:
    3.5 rating

    Metoprolol for Atrial fibrillation

    Morning dizziness, but after about 1 hour passes. Slight depression associated with the fact that I am now required to take medication. But the habituation has already occurred .. However, now begins the discipline. Because when there are no more symptoms to be observed, the brain has to work. With hello, take your tablets.

    Side effects: Dizziness
  9. Dorothy E. Melancon says:
    4.5 rating

    Metoprolol for Migraine

    Originally my migraine should be treated nevertheless my high blood pressure was to be treated in one stroke after long hesitation I took this drug only because the side effects are so strong but I was really helped my migraine which was already several times a week I could get a grip My high blood pressure was still there and got worse than better no idea but the doctors have not been under control

    Side effects: High blood pressure
  10. Lisa D. Hopkins says:
    3.5 rating

    After thirty years, the side effects become so pronounced that they are no longer reparable. Now the side effects I have: High blood pressure (167/86/71), palpitations-fast pulse, tinnitus, cold feet, itching ..

    Side effects: High blood pressure
  11. Christina T. Ford says:
    4.5 rating

    I take metoprolol for migraine and infarction prophylaxis only recently, the side effects are, I can only agree, not insignificant: Tiredness, listlessness, sweating and my depression came back. However, this may be related to the fact that I have a very low blood pressure by nature and a resting heart rate of 2 strong migraine attacks with aura per week: a normal libido, creativity, enjoyment of the beautiful things, inventiveness. Because of the depression, I’m back in treatment and I’m sure that the nausea and fatigue is still relativized a little. With weight gain I have so far no problems, I have rather decreased (less frustration than with migraine, and weight gain because of drugs is fast for me (with cortisol 15kg in 2 weeks)).

  12. Lee D. King says:
    2.5 rating

    Metoprolol succinate 98mg 1– led to heavy daytime fatigue after dose adjustment. After getting enough sleep (8 hours) he fell asleep several times on the way to work at a red traffic light. Listlessness, sadness!

  13. Victoria C. Hamblin says:
    2.0 rating

    Metoprolol for Migraine

    Strange effect of Metoprolol Since my youth, I suffer from migraines and headaches alternately with all forms of pain. (half-sided / front / back / upper head / behind the eyes / temples -two-sided-one-sided / piercing / oppressive / throbbing) Father and mother had the same problem. I myself felt pretty helpless, because I did not smoke, did not drink alcohol, did a lot of sports and ate a reasonably healthy diet. Also, I have not been able to detect any reaction to certain foods or derive any factor from other events to which I could attribute the headache, except that the pain often occurred in the morning after exercise. For decades, I dragged myself through life with normal painkillers and stood next to me for quite a few days a month before seriously considering going to the doctor with this problem. Especially during my period I suffered from 5-6 days of pain, in addition to the weekly headache. My family doctor prescribed triptans for me, without testing me for migraines in any way. But the medications helped reliably and I was glad to finally have a remedy that helps. I took different Triptan varieties for almost 3-4 years, which all helped well. At some point, however, I decided to tackle a pain therapy. Because of my low blood pressure, I got a stabilizing drug, which had no effect on the headache. Then I got Cymbalta, Lyrica and Katadolon prescribed. Again, there was no positive trend in pain. Accompanying, I had received 12 osteophatic treatments. Even that did not work out much. An MRI excludes cerebral reasons. Then I was referred to the neurologist who prescribed the beta-blocker metoprolol. At first, I was skeptical, as this drug would lower my already low blood pressure even lower. But I was ready for anything that promised hope. After slow dosing (25 mg in the evening, after 3 days 25 mg additionally in the evening, then slowly dosed up to 50 mg in the morning and in the evening) I am blindingly. After 3 months of taking it, I still can not believe it protects me from morning headaches. By agreement I had already discontinued Lyrica and Katadolon for a long time; today I take Cymbalta 30 mg every 2 days in addition to 2 x 50 mg metoprolol. My attitude to life has increased enormously Rarely do I have a slight pressure in my head, which then disappears by itself. As side effects of Metoprolol occur that I am freezing fast, I have almost constantly cold fingers and slight circulatory problems in the fingertips, but disappear by hand gymnastics again. What I find distressing is that I am slowly but steadily gaining weight since taking it. (July 65 kg – October 68.5 kg) I will slowly reduce the dosage from 2 x 50 mg to 2 x 25 mg and keep an eye on my weight.

  14. Dominic M. Jenkins says:
    3.0 rating

    Metoprolol for High blood pressure

    Who has the same side effects from ramipril (2.5mg) I am 45 years, 172 cm tall and weigh 72 kg, BMI 24, athletic (daily 60 min cycling or walking) In April of this year I had to go to a hospital, because of my spine , When ECG I was asked if I had ever had a heart attack, which I said no. The next day I was given a heart catheter and attested that I did not have an infarct, but …. Please read the result in the attachment. Then I was treated by the family doctor with metoprolol and ramipril and had pretty much all the side effects that are in the leaflet. Metoprolol was replaced by Nebilet in July. Since then, the side effects are lower, but it has adjusted to a daily irregular heart pressure and a heart piercing around the heart. The main pain is about four fingers above the left nipple, a stabbing pain that lasts about ten minutes and gradually fades away. Sometimes it also starts at the top of the heart and stops after 360 degrees. It means that the pain will march around the heart once within several hours, once it is more of a pressure, the next moment is a sting. Since my last visit to the cardiologist, to whom I have again told everything in detail, I should now additionally take morning and evening 1 PENTALONG tablet. Five months ago, I did not have anything yet and now I swallow six tablets daily. Is that the last word of wisdom? Where does that come from? Is it dangerous? Is it the medication? Are there any alternatives to my medications that will fix the problem? Unfortunately, since I have to take the medication, I do not feel well at all and do not dare to burden myself with cycling like I did before, because I’m afraid that I’m trying too hard and I suffer a heart collapse.

    Side effects: Heart ache
  15. Nathan L. Cooper says:
    2.5 rating

    Metoprolol for Heart attack

    Can not be worse, trepidation and uncontrollable chest pain on sternum, feels like re-infarction. Weight loss and constant intoxicating cough. Causes panic attacks.