About Metformin

3.0 rating based on 93 ratings
Rating: 3.1 Reviews: 93
About Metformin

Metformin lowers blood sugar levels. It is used to treat obese patients with type 2 diabetes mellitus if the high blood sugar level can not be normalized in the long term with either diet or exercise therapy.

What is the purpose of this ingredient?

  • Lower blood sugar levels
  • Inhibit sugar production in the liver
  • Improve sugar utilization
  • Reduce sugar intake from the intestine into the blood

This is how Metformin works

Below you will learn more about the fields of application and the mode of action of metformin.
Please also read the information on the drug group oral antidiabetics,
to which the active ingredient metformin belongs.

Application of the active substance metformin

Metformin lowers blood sugar levels. It is used to treat obese patients with type 2 diabetes mellitus if the high blood sugar level can not be normalized in the long term with either diet or exercise therapy.

For the following uses of Metformin , in-depth information is available:

  • Type 2 Diabetes Mellitus

Action of Metformin

Metformin belongs to the oral antidiabetics. It lowers the blood sugar level in three ways. By:

  • Inhibition of the body’s production of sugar in the liver
  • Improving sugar utilization in body cells, especially in muscle tissue
  • Preventing the absorption of sugar from the intestine into the blood. As a result, on the one hand, sudden increases in blood sugar, so-called blood sugar peaks, are avoided. On the other hand, the calorie intake is reduced, which facilitates a weight loss of the overweight diabetic

The success of treatment with metformin is indicated by the decrease in the red blood pigment (hemoglobin) bound sugar (HbA1c value). This value is important for the long-term control of blood glucose concentration.

Because metformin does not affect insulin release from the pancreas, the occurrence of hypoglycaemia is not expected.

Potential Metformin side effects may include:

Metformin used to treat the following diseases:

  1. Fay C. Coleman says:
    3.5 rating

    Metformin for Diabetes mellitus type ii

    I took the medication and I was fine with it and then after a short time I had diarrhea and vomiting. that stops after 5 weeks in I had lost 5 kilograms. After a few months, I had gained 10 kilograms. Of course, this can not be sensible or purposeful. In addition, I noticed that has stored in my lower legs water.

  2. Daniel S. Mallon says:
    3.0 rating

    Metformin for Diabetes mellitus type ii

    Metformin: I feel no change in my illness. Actos: Morning u. Evening 15mg, the effect is fantastic, insulin consumption drops by about 60%. Side effects: Eczema on the scalp, on the face, water retention in the legs and eyes, medication discontinued.

    Side effects: Water storages
  3. William W. Meyer says:
    3.5 rating

    Metformin for Diabetes mellitus type ii

    Starting visual disturbance, blurred vision; Weight gain well 35Kg in the 5 years; Impotence and constantly tired, as well as mad pain in the large joints, especially the knee joints. Every way is too far and hurts. Enormous water retention in the lower legs. Sleep disorders; If it takes a long time to sleep at most 2 hours at a time and erectile dysfunction. On the whole side effects only become aware of through conversations with other patients, only then / now only read the leaflet. The treating diabetologist did not notice anything during the whole time. New doctor’s appointment is already, then he has to come up with something. I’m so sorry! Actually, I could have read the note from Actos 45 right away, but I followed the doctor’s instructions and took it nicely. Never again!

  4. William J. Munson says:
    3.0 rating

    Metformin for Diabetes mellitus type ii

    After years of hassle-free therapy, suddenly metallic taste in the mouth, Krea values increased alarmingly. Drug currently discontinued. Increase in sugar levels after setting at 200 – 450 mg / dL

    Side effects: Taste alteration
  5. Kimberley G. Baptist says:
    3.0 rating

    Metformin for Diabetes mellitus type ii

    It is the second time that I get a cortisone therapy over 5 days. the first time it was 1000 mg. now 500 mg.Today comes the third infusion. This time it is also gods thanks to outpatient, but work and so is still not. Last red head and totally aufpuscht. You can not really sleep and do not rest and do not really do anything. Sometimes not even sleeping properly. Feels bloated (especially in the evening) and often has to water, because I also drink a lot, because I always get animal thirst and unfortunately always a bitter taste in the mouth. Also, I still have a pressure on my ear. That’s what I love about it. It gets harder every day, but it can be tolerated since I can go home after the infusions. It’s a pity that you are unexpectedly missing at work and then get back in again, although you are still a bit exhausted. Still had red, hot head and pressure on my ear the last time. Hope this will be better this time! I wish you all the best!

    Side effects: Taste alteration; Flatulence
  6. Charles C. Holloway says:
    3.5 rating

    Metformin for Diabetes mellitus type ii

    August 2013 Diabetes 2 was diagnosed and prescribed 1000mg metformin twice a day. Sugar levels have dropped and no side effects except for emaciation.

    Side effects: Weight loss
  7. Tomika R. Garcia says:
    4.0 rating

    Metformin for Diabetes mellitus type i

    For almost 3 months, in addition to Novorapid, I take half a tablet of metformin in the evening before eating. My problem was that the insulin was very sluggish in the evening and I later always had high values before going to sleep. This problem has almost disappeared since the use of metformin. I take half a tablet in the evening (after consultation with my doctor) and can really report only a positive course. I had no side effects. Nothing to feel nausea, diarrhea, depression or anything like that. But it is probably also due to the very low dose (just half a tablet once in the evening). The only nice side effect was that the cravings disappeared in the evening. Have now lost even 7 pounds. Probably not just because of the metformin, but it did not bother me :-).

    Side effects: Weight loss
  8. Gertrude S. Metcalf says:
    4.0 rating

    Metformin for Fertility disorders; Diabetes mellitus type ii

    The drug needs to be crept in. I started with 1 tabl. / day and am now at 3 pcs / day. The initial diarrhea has given complete, as well as the nausea in the first days. I still have an appetite loss, but I’m not really sad about that, so it has a positive side effect. In addition, with the help of metformin, I have already lost 7 kg and I think that was only the beginning. I do not like crystal sugar any more, I have a terrible feeling in my mouth, which is why I do not eat sweets any more.

    Side effects: Weight loss; Anorexia; Nausea; Diarrhea
  9. Lan T. Stephens says:
    3.5 rating

    Metformin for Polycystic ovaries

    Cycle has normalized from an average of 40-170 days to a cycle length of 28-33 days. Decrease to 10 kg in one year. Side effects such as nausea, diarrhea and flatulence were severe at baseline, but disappeared within a few days and are rare and weak.

  10. Mamie A. Sever says:
    4.0 rating

    Metformin for Diarrhea

    my experience with metformin medicament turns out to be an evening meal. At night, they woke up with severe abdominal pain resulting in stomach cramps, with diarrhea and a feeling of vomiting. At night it was so bad that my friend thought he must call ambulance

  11. Nancy P. Cahill says:
    4.0 rating

    Metformin for Polycystic ovaries

    I have been suffering from PCO syndrome for years. The whole thing turned out last year when I was at the gynecologist because of my desire to have a child. Unfortunately it is so much that I have too many male hormones and this leads me to almost half a year Metformin was prescribed to me last year. The first week I was supposed to take one tablet in the morning, the second week in the morning and evening one tablet and in the third week, then in the morning, at noon and in the evening one tablet. Compatibility was with me so bad that I have the tablets then completely discontinued after 23 days. I suffered from diarrhea and severe stomach cramps, which meant that I could hardly move at the end. Two days after stopping the tablets, the side effects were direct disappeared. The doctor told me that an absolute incompatibility occurs very rarely, but well, with me it was really hard, he ha He said that the first few days can be nausea and diarrhea, but nobody thought of that, especially not for three weeks. I have been taking Siofor since last week and the effect is great, I got my days directly 2 days after my first tablet. Although suffering from diarrhea, but not so strong and that sounds slow.More I can not unfortunately say to Siofor.

    Side effects: Stomach cramps; Diarrhea
  12. Ken N. Rodriguez says:
    3.5 rating

    Metformin for Diabetes mellitus type ii

    After the predecessor drug was withdrawn from the market, I received metformin in collaboration with Repaglinid. The effect has been satisfactory so far and, apart from increased hair loss / constipation, no discernible side effects are known. But it can also come from other medicines, as I regularly take tablets with a shovel.

    Side effects: Hair loss; Constipation
  13. Judith G. Holliday says:
    3.5 rating

    Metformin for Diabetes mellitus type i

    Type 1 Diabetes: As a supplement to insulin for insulin resistance and additional sports and diet. Initially significant improvement in blood sugar levels, reduced insulin requirements, weight loss. Side effects: at the beginning of taking stomach pain and nausea, dizziness. After 2 months, very severe hair loss, lessening the effect of metformin, no further weight loss. Finally discontinuation of metformin after 4 months.

  14. Marguerite S. Barajas says:
    4.0 rating

    Metformin for Diabetes mellitus type ii

    I have had diabetes mellitus type 2 for over a year and will be treated with metformin 850 mg 2 times a day. My Hba1c values have become so good that my doctor said they have no sugar at all! Which is wrong, of course! I’ve just kept up with diet and medication! But under the high dose metformin I had persistent nausea, so I did not know one more and took in addition MCP and travel pills. Finally, I’m allowed to inject a depot insulin! This relieves me clearly and there are no more food cravings and sweats!

    Side effects: Sweats; Hot hunger attacks; Nausea
  15. Ida M. Williams says:
    3.5 rating

    Metformin for Diabetes mellitus type ii

    by order of the internist – test phase now for 2 weeks – morning 1 Jardiance 10 mg very good tolerability. In the evening 1 metformin – result – severe flatulence, upper abdominal and abdominal pain (hopefully not pancreas – which is described in the leaflet) decreased about 2 kg – probably due to increased urinary excretion after about 2 hours after taking metformin cravings for sweets and strong hunger. I take the tablet for dinner before 18.00 clock.

  16. Jenine N. Norman says:
    4.0 rating

    Metformin for Diabetes mellitus type ii

    Contrary to many statements f. Appetite decrease: cravings and cravings for sweets, which was not available before ingestion. In addition, unpleasant strong sweating and constant flatulence!