About Metformin

3.0 rating based on 93 ratings
Rating: 3.1 Reviews: 93
About Metformin

Metformin lowers blood sugar levels. It is used to treat obese patients with type 2 diabetes mellitus if the high blood sugar level can not be normalized in the long term with either diet or exercise therapy.

What is the purpose of this ingredient?

  • Lower blood sugar levels
  • Inhibit sugar production in the liver
  • Improve sugar utilization
  • Reduce sugar intake from the intestine into the blood

This is how Metformin works

Below you will learn more about the fields of application and the mode of action of metformin.
Please also read the information on the drug group oral antidiabetics,
to which the active ingredient metformin belongs.

Application of the active substance metformin

Metformin lowers blood sugar levels. It is used to treat obese patients with type 2 diabetes mellitus if the high blood sugar level can not be normalized in the long term with either diet or exercise therapy.

For the following uses of Metformin , in-depth information is available:

  • Type 2 Diabetes Mellitus

Action of Metformin

Metformin belongs to the oral antidiabetics. It lowers the blood sugar level in three ways. By:

  • Inhibition of the body’s production of sugar in the liver
  • Improving sugar utilization in body cells, especially in muscle tissue
  • Preventing the absorption of sugar from the intestine into the blood. As a result, on the one hand, sudden increases in blood sugar, so-called blood sugar peaks, are avoided. On the other hand, the calorie intake is reduced, which facilitates a weight loss of the overweight diabetic

The success of treatment with metformin is indicated by the decrease in the red blood pigment (hemoglobin) bound sugar (HbA1c value). This value is important for the long-term control of blood glucose concentration.

Because metformin does not affect insulin release from the pancreas, the occurrence of hypoglycaemia is not expected.

Potential Metformin side effects may include:

Metformin used to treat the following diseases:

  1. Susan R. Lee says:
    4.5 rating

    Metformin for Polycystic ovaries

    I take Metformin 500 3 X daily because of the disease PCO syndrome. KInderwunsch is present for 5 years and the rule has remained completely since the age of 18 years. In these years, much increased, without eating differently. With Metformin 500 I now have a regular (to the exact day) period and in the 8 months have lost about 17 pounds and even had an ovulation last month. In the beginning, had to deal with diarrhea, but after a few weeks was fixed. Can only recommend this drug. I am not a diabetic but still insulin resistant. Unfortunately, the PCO syndrome is not well known to the doctors. Am glad after many years to have come to a gynecologist with knowledge of this disease (metabolic disorder). This drug is an off-label use for this disease, so I get a private prescription and have to buy it myself for about 14 euros a month.

    Side effects: By snowfall
  2. Donna E. Townsend says:
    4.0 rating

    Metformin for Diabetes mellitus type ii

    Metformin as discussed, slowly crept in. At a dose of 1000mg daily abdominal pain and diarrhea began. On demand, nevertheless, gradually increased the dose to 2x850mg. Unfortunately, severe diarrhea with acute burning on the anus, severe stomach / intestinal spasms, nausea, loss of appetite.

  3. Antonia B. Hall says:
    4.0 rating

    Metformin for Diabetes mellitus type ii

    Stomach and intestinal complaints despite the avoidance of diarrhea-promoting foods (fruits and fatty foods). Unimpeded almost daily occurring, sudden diarrheal attacks up to 4 times a day. Fatigue and fatigue and probably also limited drug efficacy due to the disturbed food utilization and the water balance.

    Side effects: By snowfall; Fatigue
  4. Sharon J. Lockhart says:
    3.0 rating

    Metformin for High blood pressure; Diabetes mellitus type ii

    Taking 3000 mg metformin daily (1000/0/2000) over 4 months. During this time, my HbA1c value has improved from 11.8 to 5.8 and I only lost 19 kg with the switch to a 3-meal rhythm. I feel like I was born again. Again fit and clearly powerful side effects: defecating bowel movements every 2 days, reduced appetite

    Side effects: Appetite loss; Diarrhea
  5. Irene G. Smith says:
    4.0 rating

    Metformin for Diabetes mellitus type ii

    After having treated my type II diabetes through diet and exercise alone (under medical supervision), the values got mixed up in the fall of last year. The fasting sugar daily was over 130 to 170 mg / dl. Then I was prescribed metformin. After initial diarrhea (about 2 days), I initially tolerated the drug very well – except for constant bloating. My blood glucose levels developed fantastically and were better than during the whole previous therapy period. After 2 months of taking time I had for the first time in my life an acute episode of psoriasis (head, genital area – very uncomfortable !!!, thighs, elbows and hands). The prescribed (cortisone-containing) ointments did not help, but thanks to MF, my sugar levels remained good, despite cortisone. After I discontinued MF at the end of January on the recommendation of the dermatologist, psoriasis healed spontaneously. Since my sugar levels were initially within tolerable range again, the doctor agreed that I would not take medication at first. Now the values play crazy again (fasting sugar up to 200 mg / dl) and also the long-term sugar has risen for the first time, instead of falling, so that I now get another medicine. The doctor does not want to prescribe me because of the side effects observed with me MF. What’s more: Here write all of weight loss, I was ALWAYS hungry under the intake of MF and since my blood sugar levels were still good, if I have eaten more (including carbohydrates), I have given in to my hunger. With the success that I have gained 9 pounds from the year before, I lost 15 pounds (this weight I had also kept 1 year). Now without MF I’m not so hungry and I am slowly but steadily decreasing. Can anyone explain to me?

  6. James M. Freels says:
    2.0 rating

    Metformin for Diabetes mellitus type ii

    I report as a relative, I’m sure it improves the sugar levels. But mean, if it does not increase your appetite? And thereby promotes an increase in weight?!.

    Side effects: Appetite increase
  7. Mark E. Villegas says:
    4.0 rating

    Metformin for Diabetes mellitus type ii

    I took metformin for two weeks. At first only diarrhea was seen as a side effect, but the skin started to itch more and more. After consulting my dock, I should divide the tablets and halve the dose. Then on the 13th day the itching got too big and my hands got fat, my lower leg aos looked as if a whole swarm of mosquitoes had caught me. (Allergic shock).

  8. Tonya R. Feinstein says:
    4.5 rating

    Metformin for Overweight; Diabetes mellitus type ii

    By taking metformin 2 x 1000 mg no real improvement in sugar levels, long-term value: 11.5. Glimepiride 1 x 3 mg prescribed after 4 months, significant improvement in blood sugar levels. Simultaneously with Glimepiride also started with Victoza, because of massive overweight. Victoza 0.6 ml for the first two weeks, then 1.2 ml in the evening. Compatibility of Victoza very good, since the beginning with 1.2 ml evening steady weight loss (decreased in 10 days 3 kg). No nausea, rarely headache but fluctuating blood pressure, mostly high. Hunger feeling and appetite are almost completely gone. After one month glimepiride discontinued, sugar levels continued to be good: about 130 in the morning

    Side effects: Anorexia
  9. Abraham G. Criddle says:
    2.5 rating

    Metformin for Overweight

    Slight complications in the form of increased sweating, rapid weight loss from average. 4kg / week.

    Side effects: Sweat; Weight loss
  10. Jeniffer L. Medina says:
    4.5 rating

    Metformin for Kinderwunsch-treatment; Polycystic ovaries

    I take 2xtägl. 850 mg metformin, because of PCO and irregular cycles. I have no insulin resistance, I am normal weight and take metformin mainly because of having children. The cycle got off to a good start in just a few weeks and became pregnant in the third metformin cycle. I had side effects like diarrhea and nausea at the beginning quite often, now and then, but I can handle that.

    Side effects: Nausea; Diarrhea
  11. Katrina M. Hetherington says:
    4.0 rating

    Metformin for Kinderwunsch-treatment; Polycystic ovaries; Diabetes mellitus type ii

    We were after about 3 years of having children in a KIWU practice. There, after he saw me, the doctor immediately took insulin resistance and wanted to test it immediately. This has also been confirmed. I then got prescribed metformin and lost 5 pounds immediately after about 30 days. Then the ovulation was triggered, because there has finally formed a beautiful. After very bad prognosis and SG of my husband OAT III we have thanks to the help of Metformin’s a 9 months old son. I would like to encourage them and hope that some people will feel the same way and they are lucky enough to get pregnant with the help. Now I take metformin again but not because of the desire for children but because of a permanent decrease. Since my liver values were also very high, I hope it works better this time.

    Side effects: No side effects
  12. Kellie R. Murphy says:
    4.5 rating

    Metformin for Fertility disorders; Polycystic ovaries; Diabetes mellitus type ii

    Unfortunately, extreme diarrhea with metformin (initially 2×450 mg / day, then 1x 850 mg / day, then 2×850 mg / day). Unfortunately, it did not get better, but it will continue, as it can allegedly achieve very good results in PCO patients who at the same time have insulin resistance and want to fulfill their long-awaited desire to have children. My diabetologist advised me then I could take a drug for diarrheal diseases at the same time. You would not become dependent on it, and it would not hurt the body. So I could then benefit from the good effects of Metformax. Will that try now. Good luck to you all!

    Side effects: Diarrhea
  13. Jill J. Sandoval says:
    4.5 rating

    Metformin for Diarrhea

    I should increase the dose of Metfromin 1000 weekly by 1/2 tablet until I reached the dose of 1-0-1. I should take the first dose 1 / 2-0-0 for two weeks. Diarrhea occurred from 1 / 2-0-1 / 2. I was told that they would stop by themselves. So I kept increasing the dose by a 1/2 tablet weekly until I reached the prescribed dose of 2-0-2. However, the diarrhea got worse and worse until they reached a watery stage. They appeared unprepared for an attack, with no previous abdominal cramps. The water just started to leak, no matter where I was. I could not keep up with my work (after all, as a teacher, I can not just run from the classroom to the bathroom in the middle of class). The end was that I shit several times and went to bed at night, because the diarrhea was so sudden and fluid that I could not make it to the Kloo. I then discontinued Metformin 1000. After two days, the diarrhea was completely over. Four months later, I tried taking it again. Already at 1 / 2-0-1 / 2 tablets, the aqueous diarrhea began again, this time even more violent and even two days later even bloody. Already one day after discontinuation of metformin has set a completely normal bowel movement again. Well, I can not use metformin.

    Side effects: Diarrhea
  14. Guadalupe J. Underhill says:
    4.0 rating

    Metformin for Diarrhea

    As long as I have taken metformin I have had most unpleasant side effects in the form of diarrhea, severe, sudden diarrhea. Unfortunately, I did not say that clearly enough to the doctors in Berlin and Leipzig. It even came to the fact that I did not come to a toilet in time (spare me – and the inclined reader-inside) more descriptions, at least then I changed my eating and Ausgehverhalten (never ate before appointments) and am also much lonelier become. All this was only when I was switched to insulin syringes.

    Side effects: Diarrhea
  15. Frances S. Wert says:
    4.5 rating

    Metformin for Hyperinsulinemia

    Take metformin because of hyperinsulinemia and hyperandrogenemia in obesity. From my endocrinologist I got prescribed metformin and I’m totally unhappy I have not lost weight but my hormone levels have improved. Have constant diarrhea and am always tired and listless. Pure catastrophe does not even get the household on the line.

    Side effects: Fatigue; Diarrhea