What side effects can Rizatriptan have?
Below you will find the most important information on possible known side effects of Rizatriptan.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).
Common side effects:
dizziness, dysphagia, headache, drowsiness, abnormal sensation, hypersensitivity, nausea, dry mouth, indigestion, abdominal pain, fatigue, abnormal temperature sensation, chest pain, flushing, throat tightness, skeletal pain, blurred vision, increased sweating, abnormal Heartbeat, reduced sensation of touch stimulation (hypoaesthesia), diminished attention, palpitations, heart rate increase (tachycardia), shortness of breath, sensation of flushing (flushing), feeling of heaviness in certain parts of the body.
Uncommon side effects:
tremors, dizziness, involuntary muscle tension, diarrhea, dysphagia, flatulence, constipation, pain, weakness, fever, anxiety disorders, sleep disorders, confusion, nervousness, agitation, decreased concentration, euphoria, depression, altered thinking, depersonalization , Inflammation of the nose, laryngitis, sinusitis, pharyngitis, backache, arthralgia, arthrosis, muscle weakness, itching, palpitations, hearing disorders, earache, taste disorders, thirst, dehydration, frequent urination, low blood pressure, disorder of coordination of movement (ataxia), disorientation, blurred vision, Blood pressure increase (hypertension), hives (urticaria), neck pain, tension in certain body regions, stiffness.
Rare side effects:
Fainting (syncope), taste disorders (bad taste), circulatory disorder of the heart (myocardial ischemia), myocardial infarction, circulatory disorders of the brain, respiratory sounds (rales, expiratory gills), facial water retention (facial edema), angioedema , Tongue swelling, laryngeal swelling, skin rash, skin lesions such as Lyell’s syndrome, facial pain, muscle tension, muscle relaxation, slowed reflexes, tongue paralysis, lip inflammation, regurgitation, nonspecific gastrointestinal disturbances, heartburn, hiccups, esophageal spasms, gastric ulcers, salivary gland pain, oral mucositis, toothache, leg pain , Memory loss, depression enhancement, altered dreams, personality disorders, hyperventilation, skin rash, slow heartbeat, sensitivity to noise, calcium deficiency, hypoglycaemia, nocturnal urination, kidney pain, urine stains, nosebleeds, skin bleeding, lymph node disease.
If rizatriptan is used too frequently, you may experience chronic, daily headaches or headaches.
What interactions does Rizatriptan show?
Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).
Co-administration with rizatriptan and MAO inhibitors or St. John’s Wort and the propranolol drug from the beta-blocker drug class may cause a serotonin excess in the brain (serotonin syndrome). It can cause symptoms such as fever, chills, tremors, nausea, high blood pressure, diarrhea and arrhythmia.
Serotonin syndrome, as well as increased blood pressure or constriction of the coronary arteries, may also occur when rizatriptan is co-administered with selective serotonin reuptake inhibitors such as citalopram, fluoxetine, paroxetine, sertraline or methylergometrine.
Rizatriptan blood levels increase with the concomitant use of fluvoxamine or oral anticonvulsants (contraceptive pill or hormone therapy during menopause). However, no increase in the incidence of rizatriptan has been reported so far in this context.
Concomitant administration of rizatriptan and ergotamine or ergotamine derivatives (including methysergide) or other 5-hydroxytryptamine receptor agonists (eg sumatriptan, zolmitriptan, naratriptan) should be avoided as the effects of the agents are mutually reinforcing. In particular, the risk of high blood pressure (hypertension) and constriction of the coronary arteries is increased. After taking any of these drugs, at least 24 hours should elapse before rizatriptan is administered.