The following provides information on contraindications to the use of pregabalin in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should Pregabalin not be used?
Pregabalin should not be used if hypersensitivity to the active substance exists.
If pregabalin combined with other antiepileptic drugs was able to achieve good seizure control, it is still not allowed to use the drug alone. There are not enough studies on a single therapy with pregabalin.
Pregabalin may cause heart failure in elderly patients with nerve-related pain that have heart or vascular disease. In these patients, the doctor should use pregabalin only with caution.
Because pregabalin is excreted almost exclusively via the kidney, the doctor must adjust the dose of kidney activity in patients with kidney disease.
In the multiple use of pregabalin against nerve pain, it has been found that the active substance is also used abusively. He should therefore be prescribed with caution by persons with caution in persons with a tendency to addiction and addiction in the medical history.
What should you watch out for during pregnancy and lactation?
In animal experiments, pregabalin caused malformations of the unborn child. Therefore, the drug should not be used during pregnancy unless the doctor clearly considers it necessary. Women of childbearing potential must use effective contraceptive methods.
It is not known if pregabalin in humans passes into breast milk. However, it was detected in the milk of rats. Therefore, during treatment with pregabalin should not be breastfed.
What should be considered in children?
The use of pregabalin in children and adolescents up to 17 years is not recommended. There are too few safety and efficacy studies in this age group so far.
Warnings and Precautions
- If taking diabetics leads to weight gain, the antidiabetics have to be dosed differently by the doctor.
- If you have swelling in your face, mouth or upper respiratory tract, stop taking it and contact the doctor.
- At the beginning of treatment, the patient should be careful, as there may be side effects on brain activity.
- At the end of treatment, withdrawal symptoms such as nausea, pain, sweating and others may occur. To prevent it, discontinue treatment with slowly diminished doses of the drug.
- The drug is not suitable for children and adolescents up to the age of 17.
- Pregnancy must be reliably prevented during treatment with the drug.
- In case of renal impairment, the doctor must reduce the dose according to the condition of the patient.
- For persons with addiction or dependence in the past history, the drug should be prescribed only with great medical care.
- The drug may cause vision impairment.
- The drug can make you feel drowsy and sleepy. This makes driving and using machines dangerous.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.