About Lyrica

3.5 rating based on 194 ratings
Rating: 3.5 Reviews: 194
About Lyrica

Pregabalin has three applications. First, it is used against neurological (neuropathic) pain in adults. Such pain occurs, for example, as a late consequence of diabetes ( type 1 or type 2 diabetes mellitus), after a nerve inflammation caused by herpes viruses and after spinal cord injuries.

What is the purpose of this ingredient?

  • relieve nerve pain
  • prevent brain cramps
  • Relieve anxiety

This is how Pregabalin works

Below you will learn more about the fields of application and the mode of action of pregabalin.
Please also read the information on the drug group antiepileptic drugs,
to which the active ingredient pregabalin belongs.

Applications of the active ingredient pregabalin

Pregabalin has three applications. First, it is used against neurological (neuropathic) pain in adults. Such pain occurs, for example, as a late consequence of diabetes ( type 1 or type 2 diabetes mellitus), after a nerve inflammation caused by herpes viruses and after spinal cord injuries.

For adult epilepsy, pregabalin is used with other antiepileptic drugs. It is effective in certain seizures originating in parts of the brain (partial seizures), including those that subsequently spread to the whole brain (generalization).

Due to its anxiolytic effect, pregabalin is also approved for the treatment of general anxiety disorders in adults.

For the following application areas of Pregabalin , in-depth information is available:

  • Pain (mild to moderate)
  • anxiety disorders
  • epilepsies

mode of action of pregabalin

The transmission of stimuli along the nerves depends, among other things, on the influx of the mineral calcium. For this purpose special calcium channels are opened in the nerve cell wall. As a result, neurotransmitters such as glutamate, norepinephrine and so-called substance P are released. These neurotransmitters trigger further reactions of the nervous system.

Pregabalin hinders the opening of the calcium channels and thus restricts the influx of calcium into the nerve endings. The increased release of neurotransmitters is thus reduced to the normal level. This helps Pregabalin relieve nerve-related pain, suppress brain cramps in epilepsy, and relieve anxiety.

Potential Lyrica side effects may include:

Lyrica used to treat the following diseases:

  1. Ralph M. Crum says:
    4.5 rating

    Lyrica for A headache; Pain (chronic)

    At first I had good results with Novalgin, then quite good results with Tramadol (Tramadolor), but the side effects: fatigue, nausea, total loss of appetite, gagging, vomiting, drying of the skin, total constipation. Since Tramadol no longer worked properly, I was prescribed Lyrica. First 150mg / day, then the double dose. The pain attenuation is good. Side effects, however, are tiredness, constipation, drowsiness, dizziness, metallic taste on the tongue, loss of libido, double vision, listlessness, flatulence, increased appetite and thus unwanted weight gain, concentration problems. The dose was further increased because within a short time the pain was back. By now I was at 450mg / day. The side effects partially sneaked out. The damping of the pain was very good. As side effects were striking: fatigue, but also sleep disorders (3 hours awake in bed at night), drowsiness (I sometimes feel like I had drunk beer), dizziness, double vision, lack of desire and listlessness, loss of appetite, appetite increase and thus weight gain (me have increased over 10kg), concentration disorders. After over 4 months of taking the drug discontinued – which cost gigantic overcoming and will – and after more than a year of abstinence from Lyrica are still some side effect is not completely gone.

  2. Jeffrey C. Cox says:
    3.0 rating

    Lyrica for Depression; Pain (chronic)

    Use in chronic cervical and thoracic pain syndrome Severe sweating at night; Tinnitus gain; lack of energy in the morning, nausea and dizziness, often blurred vision; sudden attacks of fatigue during the day; Concentration and memory impairment; Weight gain; complete libido loss – erectile dysfunction; sleep disorders

  3. Gregory C. Setser says:
    3.5 rating

    Lyrica for Sleep disorders; Pain (acute); Depression

    With the capture of Elontril I noticed immediately after the next week a clearer Verbersserrung my Depris. The nostalgia decreased very much and became much calmer. Have tried in the last 8 years a lot (psychotropic drugs), but not to compare with the Elontril. I am very grateful that it has now come against Depris on the market. Request for feedback

    Side effects: No side effects
  4. Russell M. Stratton says:
    2.5 rating

    Lyrica for Pain (back); Neuralgia

    The combination of Oxygesic and Lyrica helped me a lot. No side effects at all.

    Side effects: No side effects
  5. Lawrence M. Johnson says:
    4.0 rating

    Lyrica for Polyneuropathie

    I take z.Z. even 150 mg. I have my right leg numb to the knee and left only the foot. Water retention in both legs. The pain is limited. Walking is difficult for me. The eyes are veiled, whether that comes from Lyrica? n. On the advice of my doctor, I did not take any lyric for 3 days. Result: More water and strong, unbearable pain in the legs. I started to shiver again. The eyes have not changed. Again, depression and mood swings. Have Dan on the 4 day evening 150 mg Lyrica taken and about 2-3 hours later, at least the pain was bearable. Also my general condition improved by 100%. Since I take other medications, it is difficult to assess which side effects Lyrica causes and which are over-whitened.

    Side effects: No side effects
  6. Randall A. Ruiz says:
    3.5 rating

    Lyrica for Migraine; Pain (acute)

    Dose: 2 x daily 150 mg negative: dizziness, seizure drowsiness, difficulty concentrating, temporarily unstable gait positive: reduction of chronic stomach discomfort (reflux oesophagitis), subjective feeling of increased physical capacity

  7. David R. Glover says:
    4.0 rating

    Lyrica for Polyneuropathie

    Dizziness; Dizziness; Coordination problems that led to falls; Problems with lectures; Concentration disorders Maximum dosage 450 mg; After reduction to 150 mg extensive improvement

    Side effects: Dizziness
  8. Lee S. Avery says:
    3.5 rating

    Water retention and redness. Weight gain. Otherwise very good effect

    Side effects: Edema; Increase in weight