About Losartan

3.0 rating based on 14 ratings
Rating: 3.2 Reviews: 14
About Losartan

Losartan is used to treat non-organ hypertension (called essential or primary hypertension).

What is the purpose of this ingredient?

  • Lower blood pressure for high blood pressure
  • relieve heart in heart failure

This is how Losartan works

Below you will learn more about the fields of application and the mode of action of Losartan.
Please also read the information on the drug groups AT1 receptor antagonists, antihypertensives, to which the active ingredient losartan belongs.

Areas of application of the active substance Losartan

Losartan is used to treat non-organ hypertension (called essential or primary hypertension).

It may also be administered as a combination partner to dehydrators, beta-adrenergic blockers or cardiac glycosides for cardiac relief in chronic myocardial insufficiency. However, combination with ACE inhibitors is not permitted.

A hypotensive therapy in patients with diabetes mellitus type 2 (so-called adult-onset diabetes) and diabetic kidney disease can also be supplemented with losartan.

For the following application areas of Losartan , in-depth information is available:

  • Hypertension
  • heart failure

Effect of Losartan

Losartan belongs to the drug group of AT1 receptor antagonists. It is the only active ingredient in this group approved for the treatment of chronic heart failure (chronic heart failure).

The adrenal gland-forming angiotensin II is one of the body’s most potent hypertensive substances. This reaction is mediated by the angiotensin receptor 1 in the blood vessels and in the kidney. The AT1 receptor is responsible for the blood pressure increase. Losartan, as an AT1 receptor antagonist, selectively blocks those binding sites that require angiotensin II to increase blood pressure. As a result, the vessels expand, more water and saline are secreted and the blood pressure drops.

Losartan is taken. The maximum blood pressure reduction after a single dose occurs after approximately six hours. For long-term use, it will be achieved about three to six weeks after the start of therapy. The active ingredient is equally degraded by the liver and kidneys and excreted.

Losartan is used together with the electrolyte potassium as losartan potassium.

Potential Losartan side effects may include:

Effect
Percentage
22%
19%
14%

Losartan used to treat the following diseases:

Disease
Percentage
  1. Zachary J. Langley says:
    3.5 rating

    Losartan for High blood pressure

    Apparently no hypotensives, Losartan joint pain, muscle pain, rash and itchy, activated arthrosis pressure goes after a week taking with Cetricin, without antihystamines is nothing, a bit down 160/85 at night to rise to the 200/100. I do not want to take more Losarttan because the side effects are very marked and painful. For other antihypertensive drugs, the side effects are even more pronounced.

    Side effects: Joint pain
  2. Lionel R. Filkins says:
    2.5 rating

    Losartan for High blood pressure

    Increasing articular pains, especially in the eyes and muscles of the elbow, fibular head.

    Side effects: Joint pain
  3. Francis G. Richards says:
    3.0 rating

    Losartan for High blood pressure

    After taking losartan I had the following side effects: weight gain, heavy sweats, palpitations and shortness of breath.

    Side effects: Increase in weight
  4. William A. Ledbetter says:
    4.5 rating

    Losartan for High blood pressure

    My blood pressure became increasingly unpredictable. The values were very variable, so I got to losartan 50 and amlodipine 5 in the hospital Carvedilol 6.25. The tablet mix has initially lowered my blood pressure, but by the side effects, he rose again. I got insomnia, bladder u. Backache, irritable cough until nausea and loss of appetite. To constant belching and feeling of fullness (feeling of bursting) I had bowel movements or something similar after almost every meal. I was sore in the anal area. In addition, there was constant tiredness and dizziness. I got altered consciousness. In addition there was constant cold and encrusted nose. My eyes lit up. Exercise / sports were increasingly impossible. Driving, even cycling were no longer possible with this tablet mix

    Side effects: Cough; Dizziness; Fatigue
  5. Maria R. Edwards says:
    3.5 rating

    Hello. Since about 4 years I take Losartan bzw.Losarplus 50 / 12.5. For half a year I have a bad cough and my nose is blocked. ENT doctors can not find anything and the lung specialist is not. My doctor says that would have with any antihypertensive, did you experience it? I would be very interested in that. LG

    Side effects: Cough
  6. Terry C. Tucker says:
    2.5 rating

    cough

    Side effects: Cough
  7. Tommy A. Sisler says:
    4.0 rating

    Losartan for High blood pressure

    My doctors and I have my blood pressure under control since taking the drug. Important are simultaneous physical activities that may reduce the dose under certain circumstances. Currently I get by with a half Losartan 50 – 1 A Pharma.

    Side effects: No side effects
  8. Brian T. Sorenson says:
    3.0 rating

    Losartan for High blood pressure

    I tolerate Losartan is unlike Ramipril without any side effect. I take 2x 5mg daily. The blood pressure is only slightly increased.

    Side effects: No side effects
  9. Alanna J. Buxton says:
    4.5 rating

    Losartan for High blood pressure

    At first I was positively surprised that the stupid cough stopped under another drug …. I took the product over 1.5 years and became a permanent guest in medical practices, in the end I felt like a hypochondriac …. nosebleeds , massive muscle and joint pain, sleep impossible but leaky fatigue, dizziness attacks, bruises all over the body, fallen hands and feet and arms and legs, shortness of breath at the slightest effort, no ability to get fit, massive weight gain when I ate normal have, depression and and and it was just just corrosive. 4 weeks ago I drew a line – all complaints have gone great – unfortunately the blood pressure back up. BUT I would rather live 10 years worth living than 20 years torment me …..

  10. Joseph J. Coulombe says:
    3.5 rating

    My experience with Losartan Henning Plus 50 mg are anything but good. Tomorrow about 1 hour after taking terrible dizziness with drowsiness feeling confusion fatigue, the blood pressure goes from 150/90 to 190/105

    Side effects: Dizziness; Fatigue
  11. Marie W. Mott says:
    3.0 rating

    I can not say exactly what side effects this drug has, as I also take others. However, I have gained weight during the years of taking it and am often very tired and exhausted during the day.

    Side effects: Increase in weight; Fatigue
  12. Randy L. Woodall says:
    3.0 rating

    Losartan for High blood pressure

    At intake1 / 2 a day blood pressure goes to low, 100-58, then after 3 hours optimally 129-79, later he goes up again 159-102,

    Side effects: Dizziness; Fatigue