What side effects can Sildenafil have?
Below you will find the most important information about possible known side effects of Sildenafil.
These side effects do not occur, but you can. Because every person reacts differently to medication. Please also note that the type and frequency of side effects may vary depending on the drug formulation (eg tablet, syringe, ointment).
This list summarizes all adverse reactions reported with sildenafil for both erectile dysfunction and pulmonary hypertension. As a result, there may be duplications in the frequency specifications in individual cases.
Very common side effects:
headache, flushing and flushing, diarrhea, indigestion, body aches.
Common side effects:
Dizziness, increased photosensitivity of the eyes, blurred vision, changes in color vision (including blue eyes), retinal haemorrhages, double vision, abnormal sensation in the eye, eye irritation, palpitations, nasal congestion, runny nose and sinusitis, nosebleeds, flu , Bronchitis, cough, anemia, water retention in tissue, insomnia, anxiety, migraine, tremor, nervous disorders, burning sensations, sensory disturbances, gastritis, gastrointestinal inflammation, heartburn, indigestion, abdominal distension, hemorrhoids, cellulitis, redness, hair loss, Muscle pain, breast swelling, fever, weight gain.
Occasional or rare side effects:
hypersensitivity reactions, eye pain, redness, bloodshot eyes, hearing disorders, palpitations, cardiac arrhythmias, myocardial infarction, discomfort causing angina pectoris, sudden cardiac death, low blood pressure, hypertension, nosebleeds, loss of consciousness, cerebral hemorrhage, temporary circulatory disorders of the brain, vomiting, skin rash, erectile dysfunction, painful erection.
Side effects without frequency:
What interactions does Sildenafil show?
Please note that the interactions may vary depending on the drug formulation of a drug (eg tablet, syringe, ointment).
Some drugs delay the breakdown of sildenafil in the body and increase its action. When dosed with active substances such as erythromycin, clarithromycin and telithromycin (all for the treatment of bacterial infections), saquinavir (for HIV infection), or nefazodone (for depression) and the acid blocker cimetidine, sildenafil dosing must be reduced. The active substance should not be taken with the fungicides ketoconazole and itraconazole and ritonavir against HIV infection. Even with concomitant use of vasodilators nitro-based or alpha-sympatholytic and nicorandil there is a mutual enhancement of effect. This can lead to a sharp fall in blood pressure, blood clotting disorders, and an increase in heart rate. These drugs should not be used together with sildenafil.
Sildenafil should not be taken with grapefruit juice either. Grapefruit juice prevents the breakdown of Sildenafil in the body and increases the hypotensive effect.
Other drugs such as the antiepileptic drugs carbamazepine, phenytoin and phenobarbital, the herbal antidepressant St. John’s wort and the tuberculosis rifampicin accelerate the excretion of sildenafil from the body and thus reduce its effect.
The efficacy and tolerability of sildenafil co-administered with other medicinal products for the treatment of pulmonary hypertension from the prostaglandin drug class (