About Gabapentin

3.0 rating based on 108 ratings
Rating: 3.1 Reviews: 108
About Gabapentin

Gabapentin is used in adults and children over the age of twelve, who suffer from epilepsy that affects only part of the brain, that is, has a so-called focal origin (also called focal seizures). Seizures that spread from one point in the brain (“focus”) to the entire brain later (so-called secondary generalized seizures) can also be treated with gabapentin. For this purpose gabapentin can also be combined with other antiepileptic drugs. These combinations are already suitable for use in children over the age of three years.

What is the purpose of this ingredient?

  • Reduce overexcitability of nerve cells
  • Increase seizure threshold
  • treat certain nerve pain like diabetic neuropathy
  • treat epilepsy
  • Prevent epileptic seizures
  • Improve tremors without organic cause (essential tremor)

This is how Gabapentin works

Below you will learn more about the fields of application and the mode of action of gabapentin.
Please also read the information on the drug group antiepileptic drugs,
to which the active ingredient gabapentin belongs.

Areas of application of the active substance gabapentin

Gabapentin is used in adults and children over the age of twelve who suffer from epilepsy that affects only part of the brain, that is, has a so-called focal origin (also called focal seizures). Seizures that spread from one point in the brain (“focus”) to the entire brain later (so-called secondary generalized seizures) can also be treated with gabapentin. For this purpose gabapentin can also be combined with other antiepileptic drugs. These combinations are already suitable for use in children over the age of three years.

Gabapentin is also effective against certain adult neuralgia such as diabetic neuropathy, postherpetic neuropathy and others.

Some other diseases are also occasionally treated with gabapentin. However, these indications are not covered by clinical studies and the active substance is not approved. These include certain pains (for example, facial muscle pain), degeneration and damage to nerves (amyotrophic lateral sclerosis), complications of multiple sclerosis (trigeminal neuralgia, painful cramps and others), balance disorders with tremor, tremor, tremor without organic cause (essential tremor) or the Status epilepticus, which does not respond to other antiepileptic drugs.

For the following application areas of Gabapentin , in-depth information is available:

  • epilepsies
  • Pain (mild to moderate)

How gabapentin works

The mechanism of action of gabapentin is not yet well known. Its chemical structure is similar to gamma-amino butyric acid (GABA), an important inhibitory messenger between neurons. Nevertheless, it does not bind to the corresponding binding sites in the brain like the body’s own GABA and prevents the transmission of stimuli there. Rather, the effect seems to come about indirectly because more of the body’s own GABA is being produced. This then exerts the stimulus inhibition. It is further suspected that an influence on the metabolism of other endogenous neurotransmitters, but evidence is still pending.

Gabapentin is not effective in atrial (primary) generalized seizures, such as absences. It can even worsen this type of seizure. Its advantage is the good compatibility compared to other antiepileptic drugs. Also, gabapentin has little adverse effects on concentration, wakefulness and responsiveness.

Potential Gabapentin side effects may include:

Gabapentin used to treat the following diseases:

  1. Sharon J. Phillips says:
    4.5 rating

    Katadolon S Long 400mg: Speech stammering, dizziness, tremor Effect: Helps me in the evening better to fall asleep and the night better to cope with the pain in the back. I take the side effects into account. Gabapentin 1A Pharma 300mg: Extremely water storage Effect: The pain in the nerves is corrected quite well from Table 1 – 10 about 5 so I was satisfied but the water retention and weight gain were too strong. Once Lyrica about 1/2 year taking duration, at 2. times after 10 days the same side effects, therefore discontinued. Morphine: At the beginning of therapy extreme microsleep therefore about 1 year no car driving but after getting used to that went again. Effect: The pain is storable and I can cope with it.

  2. Jennifer S. Ramsey says:
    3.0 rating

    Thalidomide, the former thalidomide raged in my body, after many years of ingestion came insensitivity in parts of the feet, swollen tongue, which I have often bitten, then bleeding diligently, and the worst is the inner turmoil that me or not sleeps only a little, the worst in the dialysis chair, if I can not live the urge to move, there I could literally explode, after unsuccessful visits to neurologists who have prescribed me all sorts of tablets, all of which did not work, I take now After visiting the university clinic Dusseldorf, where I was finally examined properly (Dr. Husseini is just great) Gabapentin, I have to wait and see how it works in the long term. This inner unrest is a disaster, the psychological burden is enormous. I hope for improvement. Klaus Becker

    Side effects: Deafness feelings; Insomnia
  3. Sheri A. Croskey says:
    3.0 rating

    Gabapentin for Pain (acute)

    At first, I did not notice that much pain relief. After a few weeks it was better. But then trembling came on to fall asleep from hands and feet. At some point, the lower part of my face and neck was full of acne pimples. I was not sure where it came from Pontius to Pilate until I read through the internet the side effects of gabapentin again and found out that it can also be caused by gabapentin. I have not been able to reach my neurologist yet. Will clarify. I really do not feel well with it. Am 60 and have a face like a crumb cake.

    Side effects: Deafness feelings; Tremble
  4. Bess A. Meyer says:
    3.5 rating

    Gabapentin for Pain (chronic)

    Side effects are only in the first intake time occurred severe fatigue, dizziness, blurred vision, gait disorder, drowsiness. The side effects are completely gone after a few weeks. I’m almost pain free taking it. My dosage is 3 times 600mg.

  5. Diana L. Caldwell says:
    5.0 rating

    Gabapentin for Muscle cramps

    As for me with a severe form of muscle wasting and nerve damage are not insanely many things to choose from, Gabapentin was the attempt to curb the years of constant pain, so that I can keep my feet short but is more a little damper in the truest sense of the word also did not happen. A quarter of an hour after taking the spell starts and you realize that something is happening in the head. Continuous with all sorts of bearable and unbearable side effects, my life was now next to pain even after long-term side effects, when I take pills and what I can do before and after each. For me, the effects and side effects were out of proportion, so we decided to slowly lower the drug, which gave me even more side effects and withdrawal symptoms and was barely able to keep my eyes open for panic attacks, anxiety and nights of sleep. The stuff just scared me.

  6. Kenneth L. Francis says:
    4.0 rating

    Gabapentin for Neuropathy

    The drug almost did not work for me. Started with 1X in the evening 100 mg. Then increased to 3 X 100 mg. I had extreme muscle pain in my calves and joint pain in my legs as a side effect. Lastly, backache. I felt like an old man !! Have slowly dropped off again. Side effects were noticeable and fast. Never again this drug. If that is all that modern medicine has to offer, then good night !! Because rather burning soles. Maybe I will find another medicine.

  7. Werner C. Sandefur says:
    3.5 rating

    Gabapentin for Shingles

    Illness I have already 3 years and 4 months. Very severe pain in the right side of the buttocks and thighs. Taking gabapentin 400mg, first 3 days early one tablet, then early and evening one tablet, after about 4 days very strong muscle pain, back pain. During exercise, the effort was greater than before taking the tablets.

    Side effects: Back pain; Muscle aches
  8. Robert B. Johnson says:
    1.0 rating

    back pain

    Side effects: Back pain
  9. Marisol T. Brissette says:
    3.5 rating

    Gabapentin for Neuropathy

    I have been suffering from uterine neuropathy for years and have been taking 2x150mg Lyrica for 4 years. Gabapentin did not help me. Because it is unfortunately a chronic disease, I know that I can not get rid of my complaints on the whole. Despite taking Lyrica I always have this tingling and hypersensitivity. I would like to know if anyone has experience with Normast (Palmitoylethanolamide)? It iwrd claims that this drug proves itself in the short.

    Side effects: Ineffectiveness
  10. Nick C. Willits says:
    3.0 rating

    Gabapentin for Epilepsy

    I took gabapentin as an epilepsy drug, had no side effect, but no effect. In my case, a failure, I can not recommend the drug.

  11. Brenda J. Garcia says:
    4.0 rating

    Gabapentin for Nerve damage

    After initially improving post-dose pain, a steady increase in the dose was required, with the result that the side effects became serious and I am now considering withdrawing the drug. Nw with me: constant tiredness and listlessness, depressed mood, violently itchy hands and soles, blisters in the mouth, gaining weight, nightmares after a very delayed falling asleep.

  12. Tracy R. Kirby says:
    4.0 rating

    Gabapentin for Neuralgia; Pain (chronic)

    It all started with a hearing loss. As the hearing loss was treated so far, my upper jaw suddenly began to hurt. Besides, I could not control my eyes anymore. I was then hospitalized for 14 days in the hospital and adjusted to Gapabentin and Mirtazapine. In the beginning it helped me very well. After about 6 months, the first side effects occurred. These were especially diarrhea and vomiting. I was in bed almost every 14 days with an upset stomach and had cramps and diarrhea. We searched the internet for a better drug. As we discovered on a forum the Mediament Lyrica supposedly well tolerated. I then had the medication prescribed by my neurologist. Since then I take 150 mg Lyrica 3 times a day for about 1 year. I have not regretted the change since then I feel much better and almost no side effects.

    Side effects: Diarrhea; Vomit
  13. Lida E. Martino says:
    3.5 rating

    Gabapentin for Pain (neuropathic)

    Drowsiness, fatigue, dizziness, headache, nausea, unsteady gait, weakness, joint pain (arthralgia), thought disorders, memory disorders, dry mouth, depressive moods, mood swings, indigestion, myalgia, dry throat, flatulence, pancreatitis, hepatitis, jaundice, decreased responsiveness Treatment discontinuation: anxiety, insomnia, nausea, pain, sweating.

  14. Michele J. Bricker says:
    4.0 rating

    Gabapentin for Neuropathy

    The side effects with me by taking only 1x, then 2x and finally 3x a day. It went with dizziness, then I got my everyday life not regulated, the daily routines I could not coordinate. Dry mouth, was next to the track, suddenly did not see the steps of the stairs and fell down. At night in bed, when I lay and closed my eyes, the bed turned and drove carousel with me. Speech difficulties, could not speak the simplest sentences. Then I was very depressed and aggressive. The next time I howled in a tour. I did not have anything to do with myself, I was no longer myself. I discontinued this medication gradually, as it had no effect whatsoever.

  15. Jeanne W. Leonard says:
    4.0 rating

    Gabapentin for Shingles

    I was given the medication for shingles nerve pain. After only 2 days severe side effects occurred. Insomnia, tremor, drowsiness, extreme wine attacks, depressive mood, fears, Verwirtheit, dizziness and nightmares! After I got advice from a pharmacist, I stop taking the medication immediately. Although my pain was blown away, but my feeling tells me …. another 5 days and I am in psychiatry. In addition, I was completely upset. Never again this Gabapentin !!!

    Side effects: Tremble; Insomnia; Dizziness
  16. John J. Johnson says:
    2.0 rating

    Gabapentin for Polyneuropathie

    the drug gabapentin did not help me after 2 years of taking it. side effects: fatigue, nervousness, digestive problems, shakiness, sleep disorders (maximum 5 hours sleep)