Comparing with Metformin, the drug successfully applied for dozens of years. But the long-term efficacy of Forxiga has not been studied in all aspects.
Possible side effects include:
- Polyuria – increased allocation of urine;
- Polydipsia is a constant thirst;
- Polyphagia is a heightened sense of hunger;
- Increased fatigue and irritability;
- Unexplained weight loss;
- Slow healing of wounds;
- Urinary tract infections, accompanied by itching and flushing in the groin;
- Glucosuria (the appearance of glucose in urinalysis);
- Nocturnal spasms of the legs (due to lack of fluid);
- Poor neoplasia (insufficient information);
- Oncology of the bladder and prostate (unverified information);
- Violation of the rhythm of defecation;
- Intensified sweating;
- Increased levels of urea and creatinine in the blood;
- Ketoacidosis (diabetic form);
- Back pain.
It is important to remember that dapagliflozin provokes an increased work of the kidneys, over time their performance drops, as well as the rate of glomerular filtration. For a diabetic, the kidneys are the most vulnerable organ, if there are already any violations on this side, we must abandon the use of any analogs of Forxiga. The launched form of diabetic nephropathy involves the artificial purification of the kidneys by hemodialysis.
The inhibitor is dangerous to use with type 1 diabetes, because glucose, which the body receives with food, is also excreted by the kidneys. Increased risk of hypoglycemia, rapidly changing precoma and coma.
There is no clear picture about diabetic ketoacidosis. Individual cases that may be associated with other concomitant components of the metabolic syndrome have been documented.
Concurrent administration of diuretics quickly dehydrates the body and can be dangerous.