Fentanyl contraindications and warnings


Following is information on contraindications to the use of fentanyl in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should Fentanyl not be used?

Fentanyl must not be used in case of known hypersensitivity to the active substance, severe impairment of brain function or dependence on opioid painkillers. Fentanyl may only be used if it is carefully weighed by a physician and under his control.

  • permanent narrowing of the airways (COPD), other lung diseases or respiratory disorders, as these may be exacerbated by the active substance
  • Diseases or injuries that cause increased intracranial pressure or dysphagia
  • Cardiac arrhythmia with slow heartbeat in patients with low blood pressure and / or lack of blood
  • impaired liver or kidney function, the dose should be reduced by the doctor if necessary
  • elderly or emaciated patients because the dose may need to be reduced by the doctor
  • Myasthenia gravis, because the drug can cause non-epileptic seizures.

What should you watch out for during pregnancy and lactation?

The active substance should not be taken during the entire pregnancy, since it can make it dependent in the womb and trigger withdrawal symptoms in the newborn after birth.

Before or during birth (including cesarean section) given, the drug may cause an inhibition of respiratory function (respiratory depression) in the child and must therefore not be used.

Although there has been no known harm to the baby so far, the active substance should not be taken while breast-feeding as it passes into the milk. Breast-feeding is usually not necessary with single use.

What should be considered in children?

Fentanyl can also be generally used in children. At what age depends strongly on the dosage form. In any case, follow the instructions of the doctor, read the package leaflet or consult a pharmacist.

Warnings and Precautions

  • During treatment, alcohol should not be consumed under any circumstances.
  • Repeated use of opioids may lead to emotional dependence.
  • Elderly patients with low body weight and people with head injuries and brain tumors need special care during treatment.
  • Anti-epileptic drugs and sedatives (barbiturates and benzodiazepines) should not be taken during treatment.
  • The drug is subject in Germany to the Narcotics Act and is only available on a special narcotic (BTM) recipe.
  • Repeated use of opioids allows the body to get used to the drug (development of tolerance). This may require higher dosages and increase the risk of dependency.
  • The drug is classified as a doping agent in controls.
  • Especially at the start of treatment,
    Dose increase and in combination with
    Other agents may be used on an individual basis
    the reactivity impaired so far
    be that ability to be active
    Driving or operating machinery is restricted.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.