About Femara

3.5 rating based on 58 ratings
Rating: 3.6 Reviews: 58
About Femara

Most forms of breast cancer are promoted in their growth by the female sex hormone estrogen. Letrozole is used in postmenopausal women to combat such so-called hormone-dependent forms of breast cancer in order to reduce the growth of the tumor. However, the drug can also be used as a cancer medicine in patients who are due to ovarian erosion during menopause.

Letrozole is used

  • as first-line therapy after an early-stage breast cancer tumor has been removed by surgery
  • after five years of standard therapy with tamoxifen, another breast cancer medicine
  • also as first-line therapy, ie first-line therapy, in advanced breast cancer
  • in recurrence or exacerbation of breast cancer despite treatment with antiestrogens

What is the purpose of this ingredient?

  • Decrease hormone-sensitive breast cancer cells

This is how Letrozol works

Below you will learn more about the applications and the mode of action of letrozole.
Please also read the information on the drug classes aromatase inhibitors, cytostatics, to which the active ingredient letrozole belongs.

Usage of the drug letrozole

Most forms of breast cancer are promoted in their growth by the female sex hormone estrogen. Letrozole is used in postmenopausal women to combat such so-called hormone-dependent forms of breast cancer in order to reduce the growth of the tumor. However, the drug can also be used as a cancer medicine in patients who are due to ovarian erosion during menopause.

Letrozole is used

  • as first-line therapy after an early-stage breast cancer tumor has been removed by surgery
  • after five years of standard therapy with tamoxifen, another breast cancer medicine
  • also as first-line therapy, ie first-line therapy, in advanced breast cancer
  • in recurrence or exacerbation of breast cancer despite treatment with antiestrogens

More detailed information is available on the following Letrozol application areas:

  • breast cancer

Mode of action of letrozole

Before menopause, the ovaries are the headquarters of estrogen production by aromatase. There, however, aromatase inhibitors are ineffective and can not suppress estrogen production. In addition, aromatase produces a small amount of estrogen in the liver, adrenal gland, adipose tissue cells, and, fatally, in breast cancer cells. Estrogen production in these tissues is maintained even after menopause. However, it can then be blocked by letrozole. So the production of estrogen remaining after the menopause comes to a standstill.

In women with advanced stage breast cancer who are after the menopause, daily doses of 0.1 to 5 milligrams of letrozole reduce the concentration of estrogen in the blood by 75 to 95 percent of baseline.</p >

Potential Femara side effects may include:

Femara used to treat the following diseases:

Disease
Percentage
2%
  1. Vicki D. McVay says:
    3.0 rating

    Femara for Breast cancer

    severe bones and muscle pain, beginning about 6 weeks after the start of treatment, persistent

    Side effects: Muscle aches; Bone pain
  2. Susan D. Perkins says:
    2.5 rating

    Femara for Breast cancer

    Side effects of tamoxifen: hot flashes nothing else. Effects of Femara: Hot flashes less than tamoxifen. Joint pain, dehydration of the mucous membranes, loss of libido, tachycardia, frequent urination. For 5 years I took Tamoxifen, since autumn 2007 I take Femara. For about 2 months I have muscle pain in the shoulder area and strong muscle pain in the right upper arm. My GP sent me to X-ray and told me to do a scan now. Can someone tell me how long I can and should take Femara and if I can not sell it?

  3. Bernice H. Walston says:
    2.0 rating

    Femara for Breast cancer

    Bone pain (all finger joints left and right); Stiffness of the hands and leg joints / musculature) strong mood swings

  4. Andrea G. Burnett says:
    4.0 rating

    Femara for Breast cancer

    Bone pain, joint inflammation especially shoulder and elbow, morning stiffness with pain especially in the feet

    Side effects: Joints stiff; Bone pain
  5. Ana C. Rae says:
    3.0 rating

    Femara for Breast cancer

    Memory disorders, lack of strength and lack of condition, joint pain (ankles, knee joints, hips particularly affected), tingling in the legs, foot pain,

    Side effects: Joint pain
  6. Evelyn H. Morgan says:
    4.0 rating

    Femara for Breast cancer

    Increases joint pain on the spine

    Side effects: Joint pain