Entocort contraindications and warnings

Contraindications

The following provides information on contraindications to the use of budesonide in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).

When should budesonide not be used?

Budesonide must not be used in cases of hypersensitivity to the active substance and to infections, in particular of the intestine, by bacteria, viruses or fungi as well as by chickenpox and measles.

As a nasal spray (intranasal), the drug may be used in pulmonary tuberculosis, fungal diseases (mycoses) in the respiratory tract (lung mycosis) and in bacterial and viral infections of the respiratory tract only in combination with an antibacterial or antifungal treatment (anti-fungal agents).

Even when used in the intestine, the active substance in case of local infections with bacteria, fungi, microorganisms (amoeba) and viruses should not be used. It is also not possible to use it in the intestine in case of chronic adhesions (liver cirrhosis) and signs of hypertension in the hepatic portal vein, ie in the late stages of destruction of the small bile ducts (primary biliary cirrhosis).

Budesonide is not suitable for the treatment of an acute asthma attack due to the delayed onset of action.

What should you watch out for during pregnancy and lactation?

The active substance budesonide should be used during pregnancy only after medical advice and careful consideration of the benefit-risk balance. Since newborns whose mothers received budesonide during pregnancy have been diagnosed with adrenal gland dysfunction, they are advised to avoid pregnancy during therapy with budesonide.

Since budesonide, like all glucocorticoids, can pass into breast milk, it is recommended to stop it before long-term treatment or when using higher doses.

What should be considered in children?

For the use of the active substance budesonide in children, the manufacturers give different indications. Therefore, the leaflet of the respective drug should be read carefully or the doctor should be consulted.

The suppression of endogenous glucocorticoid formation can lead to growth disorders in children. Children who are treated with inhaled glucocorticosteroids for longer periods must therefore undergo regular medical checks.

Treatment with budesonide in tablet form can lead to severe disease patterns in chicken pox and measles. Budesonide should not be used as a pill or suppository in children and infants.

Warnings and Precautions

  • When used against asthma, the drug is not suitable for the treatment of acute seizures.
  • If used against asthma, the drug should be discontinued immediately if there is an acute worsening of respiratory distress.
  • The drug can reduce the body’s adaptation to stressful situations.
  • The use of the drug may cause a positive result in doping controls.
  • After prolonged treatment with the drug in tablet form, the normal adrenocortical function is only slowly restored.

Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.