The following provides information on contraindications to the use of etanercept in general, pregnancy & amp; Breastfeeding and children. Please note that the contraindications may vary depending on the dosage form of a drug (eg tablet, syringe, ointment).
When should not Etanercept be used?
Treatment with etanercept should not be started at
- Hypersensitivity to the drug, sepsis or risk of such
- Infections (including those that are chronic or local only), especially tuberculosis.
- Inflammation of the nose (Wegener’s granulomatosis)
- Other immunologic agents such as anakinra and abatacept, as serious side effects may occur
Special medical attention and consideration of the benefits and risks of etanercept treatment are required at
- Liver inflammation by hepatitis viruses, even if the disease has been around a long time. There have already been cases in which such a disease has flared up again through an etanercept treatment.
- the risk of chickenpox infection. Then the treatment should be temporarily interrupted and the doctor should perform a preventive immunization with chickenpox immunoglobulin.
- Patients with defective blood composition. If signs of a blood disorder occur during etanercept therapy such as persistent fever, sore throat, bruising, bleeding or paleness, seek medical advice immediately.
- a nervous condition like multiple sclerosis or a possible tendency to it. Etanercept should then be used only after careful medical consideration of benefits and risks and appropriate examinations.
- Heart muscle weakness as it can be enhanced by etanercept.
What should you watch out for during pregnancy and lactation?
Because etanercept has not been studied in pregnant women, the use of the drug in pregnant women is not recommended. Women of childbearing potential should use an effective method of pregnancy prevention during etanercept treatment.
It is not known if etanercept passes into breast milk. In lactating rats, however, this was the case and the drug could be detected in the blood of the kittens. Therefore, the doctor should decide whether to either wean off or stop the use of Etanercept while breastfeeding.
What should be considered in children?
From the age of four, children with juvenile rheumatoid forms can be treated with etanercept.
For the application of skin problems caused by psoriasis, the application is only allowed from the age of eight years.
Warnings and Precautions
- In case of fever, sore throat, bruising, bleeding or paleness, seek medical advice immediately.
- If you experience photophobia, short-term swindle, headache, horizontal double vision, nausea and vomiting during treatment, consult your doctor immediately.
- Treatment with the drug should be started and supervised by a specialist with experience in the diagnosis and treatment of joint inflammation and psoriasis.
Signs of tuberculosis such as persistent cough, loss of strength, weight loss and a slight increase in body temperature should be reported to the doctor immediately.
Sometimes medications release allergic reactions.
If you notice any signs of allergic reaction, tell your doctor or pharmacist immediately.