About Doxepin

3.5 rating based on 134 ratings
Rating: 3.3 Reviews: 134
About Doxepin

Doxepin is used to treat depression and anxiety disorders. It suppresses restlessness, helps with sleep disorders and functional (not physical) organ disorders. It is also used in alcohol and drug withdrawal to suppress mild withdrawal symptoms.

What is the purpose of this ingredient?

  • relieve depression
  • Release fear
  • Reduce withdrawal symptoms in alcohol withdrawal
  • Reduce withdrawal symptoms on drug withdrawal
  • Promote sleep
  • relieve functional (non-physical) organ discomfort

This is how Doxepin works

Below you will learn more about the areas of application and the mode of action of Doxepin.
Please also read the information on the drug groups tri- and tetracyclic antidepressants, antidepressants, to which the active ingredient Doxepin belongs.

Areas of application of the active ingredient Doxepin

Doxepin is used to treat depression and anxiety disorders. It suppresses restlessness, helps with sleep disorders and functional (not physical) organ disorders. It is also used in alcohol and drug withdrawal to suppress mild withdrawal symptoms.

For the following application areas of Doxepin , in-depth information is available:

  • depression
  • anxiety disorders
  • nervous
  • alcohol dependence
  • sleep

Effect of Doxepin

Doxepin is one of the tricyclic antidepressants. It has pronounced calming, anxiolytic and mood-enhancing effects.

As an action mechanism for the effect in the brain an influence of the neurotransmitters serotonin and norepinephrine is assumed. Doxepin inhibits their reuptake into the cells, thus increasing their concentration in the brain and thus unfolding its positive effect.

Doxepin also inhibits the action of the tissue hormone histamine by blocking the H1 and H2 receptors. Doxepin was used to inhibit gastric juice secretion and the development of gastric ulcers under stress in different experimental settings.

Doxepin has a weak anticholinergic and antispasmodic effect both in the brain and in the rest of the body. Like other tricyclic antidepressants, it inhibits the conduction of the heart at high doses (slowing the heartbeat) and lowers the resistance within the blood vessels slightly (lowering blood pressure).

The following effects of doxepin have also been demonstrated in animal experiments: Effectiveness of analgesics, reduction of dependence on opioid analgesics, suppression of withdrawal symptoms in morphine dependence.

Potential Doxepin side effects may include:

Doxepin used to treat the following diseases:

  1. Carol J. Williams says:
    2.5 rating

    Doxepin for Sleep disorders; Depression

    Barely able to wake up in the morning, tired during the day, grumpy, listless, unfair behavior (unconscious), no desire for sex anymore, loss of reality.

    Side effects: Libido loss; Fatigue
  2. Jason A. Jones says:
    3.0 rating

    Doxepin for Psychosis; Sleep disorders

    Solian works from a dose v. 200mg like amphetamine. I used to be dependent on Ampha for a long time, but have not taken it for 7 years now. If I take 4 x 100mg in 2-3 hours, it is better.

    Side effects: No side effects
  3. Vesta M. Brown says:
    4.0 rating

    Doxepin for Sleep disorders

    doxepin helped me a lot with the sleep disturbances. I take 1/2 tablet (12.5mg) in the evening. cancel it at the moment, because I do not think I need it anymore. I did not increase too.

    Side effects: No side effects
  4. Ethel B. Tatum says:
    3.5 rating

    Doxepin for Borderline; Depression

    I used to take Doxepin 100mg in the evening, so I was finally able to sleep again, but was tired and impotent the next day. Although I gained three kilos, which was quite desirable because I also suffered from an eating disorder, the depression could only be moderated a little. But there was no more suicide attempt. Dry mouth. Since I additionally take pregabalin (because of an accident, from it the damage of the nerves on the foot), the side effects are intensified. After taking drunkenness and strong fatigue, as well as ings. 12 kilos of weight gain. Dry mouth, but word finding problems have only been recorded since taking Pregabalin.

  5. Michael E. Lebron says:
    3.5 rating

    Doxepin for Depression

    Although the dose was only 10mg in the evening, there were many unwanted effects. Very sedating for the first few days (1.5-2 hours after ingestion). Tachycardia, dizziness and balance problems, mild confusion, strong appetite increase, nightmares, inflammatory sensation in the skin (similar to a sunburn), severe dry mouth and nasal mucosa. Some side effects have subsided after the first few days. However, the intake was not more pleasant. The in my case wanted, sleep inducing side effect also disappeared already after 6 days. In the rest of the intake, an unbearable inner turmoil and inner dryness increased with concomitantly increasing external listlessness and slackness. There were also very strong mood swings. In addition, I felt absent, standing next to myself. The absent impression and the zombie movements were also observed by outsiders. After weaning / fast weaning, all side effects have completely resolved within 2-3 days of the last weaning dose.

  6. Donald J. Geiger says:
    2.5 rating

    Doxepin for Borderline; Depression

    With Doxepin, I took 10 kilos in the same period of 6 weeks and helped me on the net. Droxsal can handle it better

    Side effects: Increase in weight
  7. Maria A. Russell says:
    3.5 rating

    Doxepin for Sleep disorders; Depression

    right at the beginning a clear increase in weight ……. despite still less eating and this consists largely of fruits and vegetables ……. stomach pain and intestinal problems

  8. Jack P. Deal says:
    4.0 rating

    Doxepin for Sleep disorders; Depression

    Helps to some extent with insomnia, but makes from 2 tablets (50mg) all day very tired and often listless. The mood enhancement is rather low, because the bruisedness outweighs.

    Side effects: Fatigue
  9. Victoria K. Snyder says:
    3.5 rating

    Doxepin for Depression

    despite low dose of 10 mg condition of permanent fatigue during the day. As a result: grumpy state of mind, because blocked, where else activity was there. But it helps against insomnia.

    Side effects: Fatigue
  10. Christine C. White says:
    3.5 rating

    Doxepin for Borderline

    · Strong weight gain in normal eating behavior – in 12 months 12 kilo, which are almost completely gone after settling within 3 months · fatigue – I felt pretty driftless